There are currently 980 clinical trials in Tampa, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Moffitt Cancer Center, University of South Florida, H. Lee Moffitt Cancer Center and Research Institute and Tampa General Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
NCT06137118
Recruiting
This is a Phase 1/2, global multicentre, open-label, single-arm, dose escalation and dose optimisation study of AZD0486 to evaluate the safety, tolerability, and efficacy of AZD0486 monotherapy in participants with R/R B ALL who have received ≥ 2 prior lines of therapies. The study will consist of 3 parts. Part A monotherapy dose escalation. Part B dose optimisation. Part C Dose expansion at the recommended phase 2 dose (RP2D)
Gender:
All
Ages:
Between 12 years and 80 years
Trial Updated:
05/20/2024
Locations: Research Site, Tampa, Florida
Conditions: B-cell Acute Lymphoblastic Leukemia (B-ALL)
Register for Updates
A Study to Test the Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease
NCT05499130
Recruiting
The primary objective is to characterize the efficacy TEV-48574 in adult participants with IBD (moderate to severe Ulcerative Colitis (UC) or Crohn's Disease (CD)) as assessed by induction of clinical remission (UC) and endoscopic response (CD) at week 14. Secondary objectives: To evaluate the efficacy and dose response of the 2 different dose regimens as assessed by multiple standard measures To evaluate the safety and tolerability of the 2 different dose regimens To evaluate the immunogenici... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/20/2024
Locations: Teva Investigational Site 15359, Tampa, Florida
Conditions: Crohn Disease, Colitis, Ulcerative
Register for Updates
Long-Term Follow-up Protocol for Participants Treated With Gene-Modified T Cells
NCT03435796
Recruiting
This is a prospective study for the long-term follow-up (LTFU) of safety and efficacy for all pediatric and adult participants exposed to Gene-modified (GM) T cell therapy participating in a previous Celgene sponsored or Celgene alliance partner sponsored study. Participants who received at least one GM T cell infusion will be asked to enroll in this LTFU protocol upon either premature discontinuation from, or completion of the prior parent treatment protocol.
Gender:
All
Ages:
All
Trial Updated:
05/20/2024
Locations: H. Lee Moffitt Cancer Center and Research Institute University of South Florida, Tampa, Florida
Conditions: Neoplasms
Register for Updates
A Novel Approach to Plantar Fasciitis in the Aging Population
NCT05834491
Recruiting
The goal of this study is to determine whether improving foot strength through foot exercises and minimal footwear can provide improved outcomes over the short and long term. The main research question it aims to answer is: Can the minimal footwear intervention be used to improve the health of aging adults with plantar fasciitis?? Participants will be randomized into 2 groups. One group will receive minimal shoes and foot strengthening and foot flexibility exercises. The other group will receive... Read More
Gender:
All
Ages:
Between 50 years and 70 years
Trial Updated:
05/20/2024
Locations: University of South Flroida, Tampa, Florida
Conditions: Plantar Fasciitis, Chronic
Register for Updates
OssDsign® Spine Registry Study ("Propel")
NCT05329129
Recruiting
The purpose of this multi-center, prospective, observational registry is to gather information on the clinical outcomes and real-world use of commercially available bone graft substitutes manufactured by OssDsign® AB, in patients who require spine fusion.
Gender:
All
Ages:
21 years and above
Trial Updated:
05/20/2024
Locations: Foundation for Orthopaedic Research and Education, Tampa, Florida
Conditions: Degenerative Disc Disease, Spinal Stenosis
Register for Updates
A Phase 2 Study to Evaluate the Safety, Tolerability, and Immunogenicity of AFX3772 Vaccine in Healthy Infants
NCT05412030
Recruiting
This is a Phase 2 clinical study to support the use of AFX3772 in healthy infants for the prevention of pneumococcal disease. The purpose of this study is to determine the safety, tolerability, and immunogenicity of 3 different dose levels of AFX3772 compared with PCV13. Infants approximately 2 months of age will be enrolled and receive 4 doses of study vaccine over 8 protocol-defined visits spanning a duration of approximately 18 to 21 months. Part 1 is the dose escalation, lead-in portion of t... Read More
Gender:
All
Ages:
Between 42 days and 90 days
Trial Updated:
05/20/2024
Locations: GSK Investigational Site, Tampa, Florida
Conditions: Pneumococcal Infections, Pneumonia, Pneumococcal, Pneumonia, Bacterial
Register for Updates
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
NCT05383274
Recruiting
Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 65 years of age.
Gender:
Male
Ages:
Between 22 years and 65 years
Trial Updated:
05/17/2024
Locations: Florida Urology, Tampa, Florida
Conditions: Urethral Stricture
Register for Updates
A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.
NCT05523167
Recruiting
This study's purpose is to measure the treatment response from efgartigimod PH20 SC compared with placebo in participants with Idiopathic Inflammatory Myopathy (IIM). Participants with the IIM subtypes of dermatomyositis (DM), immune-mediated necrotizing myopathy (IMNM), or certain other subtypes of polymyositis (PM; including antisynthetase syndrome [ASyS]) will be included in the study. Treatment response will be measured by Total improvement score (TIS). Additional information can be found on... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: University of South Florida (USF) - Morsani Center (USF Health Carol and Frank Morsani Center for Advanced Healthcare), Tampa, Florida
Conditions: Active Idiopathic Inflammatory Myopathy, Myositis, Dermatomyositis, Polymyositis, Immune-Mediated Necrotizing Myopathy, Antisynthetase Syndrome
Register for Updates
Quaratusugene Ozeplasmid (Reqorsa) in Combination With Pembrolizumab in Previously Treated Non-Small Lung Cancer
NCT05062980
Recruiting
The purpose of this study is to determine the safety and efficacy of quaratusugene ozeplasmid (Reqorsa), in combination with pembrolizumab in patients with previously treated NSCLC. Quaratusugene ozeplasmid consists of non-viral lipid nanoparticles that encapsulate a DNA plasmid with the TUSC2 tumor suppressor gene, and is a systemic gene therapy. The study will be conducted in 2 phases, a dose escalation phase (Phase 1) and a safety and efficacy evaluation phase (Phase 2). In Phase 1, patients... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Moffitt Cancer Center - Magnolia Campus, Tampa, Florida
Conditions: Non Small Cell Lung Cancer
Register for Updates
Nerve Protection Evaluation: Revision Cubital Tunnel Syndrome Decompression
NCT06117501
Recruiting
This single-cohort, prospective case series is designed to evaluate and characterize the use of Axoguard HA+ Nerve Protector™ to protect the ulnar nerve in a first revision cubital tunnel decompression procedure. Data on the primary cubital tunnel syndrome decompression, first revision decompression utilizing Axoguard HA+ Nerve Protector, participant-reported pain, motor and sensory functional outcomes, quality of life (QoL) outcomes, and recurrence/revision will be collected. This case series w... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Foundation for Orthopaedic Research and Education (Florida Orthopaedic Institute), Tampa, Florida
Conditions: Recurrent Cubital Tunnel Syndrome, Recalcitrant Cubital Tunnel Syndrome
Register for Updates
REFLECTION: A Clinical Practice Learning Program for Galleri®
NCT05205967
Recruiting
REFLECTION is a multi-center, prospective, non-interventional, cohort study that will enroll approximately 17,000 individuals who have opted to be screened with Galleri®, a blood-based, multi-cancer early detection (MCED) test in routine clinical settings. The purpose of the study is to understand the real-world experience of Galleri® in clinical settings.
Gender:
All
Ages:
22 years and above
Trial Updated:
05/17/2024
Locations: James A. Haley Veterans Hospital (VA Tampa), Tampa, Florida
Conditions: Early Detection of Cancer, Cancer
Register for Updates
Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial
NCT05478304
Recruiting
This trial is a prospective, randomized, multicenter, multinational, blinded, superiority trial. The objective of this trial is to evaluate the effectiveness of left atrial appendage exclusion (LAAE) for the prevention of ischemic stroke or systemic arterial embolism in subjects undergoing cardiac surgery who have risk factors for atrial fibrillation and ischemic stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Baycare Health System, Tampa, Florida
Conditions: Ischemic Stroke, Systemic Embolism
Register for Updates