There are currently 980 clinical trials in Tampa, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Moffitt Cancer Center, University of South Florida, H. Lee Moffitt Cancer Center and Research Institute and Tampa General Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
TBio-4101 and Pembro wi/ or w/o Chemo in Recurrent/Metastatic HNSCC
NCT06236425
Recruiting
Phase 1b open-label study to evaluate the safety of selected TIL (TBio-4101) delivered after lymphodepleting chemotherapy and followed by intravenous (IV) bolus aldesleukin (IL-2) and pembrolizumab for patients with advanced HNSCC who have initially progressed on pembrolizumab or pembrolizumab/platinum chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Squamous Cell Carcinoma of Head and Neck, Metastatic Squamous Cell Carcinoma
Register for Updates
Telemedicine-Based Virtual Reality Clinic for the Treatment of Phobias
NCT06302868
Recruiting
The purpose of this study is to assess the feasibility of conducting a randomized controlled efficacy trial comparing the delivery of exposure therapy via a telemedicine-based virtual reality clinic (Doxy.me VR) vs. standard telemental health (TMH) to adults with intense fear of dogs, snakes, and/or spiders. The secondary purpose is to preliminarily examine the efficacy of using Doxy.me VR vs. TMH in reducing phobia severity.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: University of South Florida, Tampa, Florida
Conditions: Arachnophobia, Cynophobia, Ophidiophobia
Register for Updates
Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)
NCT06305676
Recruiting
Investigators seek to determine the sensitivity and specificity of a combined HPV 16 DNA and host gene methylation oral biomarker panel to distinguish early Oropharyngeal Cancer (OPC) cases from controls among 100 early and 100 late disease pre-treatment OPC cases, and 200 controls matched by sex, age, race/ethnicity, and tobacco use collected from the Moffitt Cancer Center (Moffitt) and the University of Pittsburgh Medical Center Hillman Cancer Center (Pittsburgh).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: HPV-Related Oropharyngeal Cancer
Register for Updates
Study of CG0070 After Transurethral Resection in Patients With IR NMIBC
NCT06253845
Recruiting
Investigators will evaluate the safety of CG0070 for the treatment of patients with Intermediate-Risk Non-Muscle Invasive Bladder Cancer (IR NMIBC).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Non-muscle Invasive Bladder Cancer
Register for Updates
A Trial to Find Out if REGN5678 is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors
NCT03972657
Recruiting
The main purpose of this study is to determine the safety, tolerability (how your body reacts to the drug) and effectiveness (ability to treat your cancer) of REGN5678 alone, or in combination with cemiplimab. The study has 2 parts. The goal of Part 1 (dose escalation) is to determine a safe dose(s) of REGN5678 when it is given alone or in combination with cemiplimab. The goal of Part 2 (dose expansion) is to use the REGN5678 drug dose(s) found in Part 1 to see how well REGN5678 alone or in com... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
03/05/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Metastatic Castration-resistant Prostate Cancer (mCRPC), Clear Cell Renal Cell Carcinoma (ccRCC)
Register for Updates
ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease
NCT03671889
Recruiting
The purpose of this study is to evaluate the safety and efficacy of the ExAblate Model 4000 Type 2.0 System as a tool to disrupt the blood-brain barrier (BBB) in patients with probable Alzheimer's Disease (AD).
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
03/04/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Alzheimer Disease
Register for Updates
A Study of Amivantamab in People With Esophagogastric Cancer
NCT05117931
Recruiting
The purpose of this study is to see whether the study drug, amivantamab, is an effective treatment for people with EGFR- or MET-amplified esophagogastric cancer. The researchers will also look at whether amivantamab is a safe treatment that causes few or mild side effects in participants.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Esophagogastric Cancer
Register for Updates
Study to Evaluate the Safety and Tolerability of Single-Dose Intravenous (IV) Oritavancin
NCT05599295
Recruiting
This protocol describes a randomized, open-label study to evaluate the safety and tolerability of single-dose intravenous (IV) oritavancin diphosphate (oritavancin) versus standard of care (SoC) antibiotics for the treatment of pediatric subjects with acute bacterial skin and skin structure infections (ABSSSIs). This study involves two oritavancin products, ORBACTIV® and KIMYRSATM. Oritavancin is the active drug substance in both ORBACTIV and KIMYRSA. This study protocol distinguishes the diffe... Read More
Gender:
All
Ages:
Between 3 months and 17 years
Trial Updated:
03/04/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Acute Bacterial Skin and Skin Structure Infection
Register for Updates
A Phase 3 Study of Rusfertide in Patients With Polycythemia Vera
NCT05210790
Recruiting
The study is designed to evaluate the safety and efficacy of rusfertide in subjects with polycythemia vera (PV) in maintaining hematocrit control and in improving symptoms of PV.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/03/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Polycythemia Vera
Register for Updates
Efficacy of Implantable Defibrillator Therapy After a Myocardial Infarction
NCT00673842
Recruiting
This study will assess whether an implantable defibrillator will increase the likelihood of survival in patients who have had a heart attack, have abnormal test results from a 24 hour heart monitor, and who have low normal heart function.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/01/2024
Locations: James A Haley Veterans' Center, Tampa, Florida
Conditions: Myocardial Infarction, Sudden Death
Register for Updates
Sponsor-Initiated OCS Heart Perfusion Registry
NCT05915299
Recruiting
OHP-II Registry is a sponsor-initiated, multi-center, observational post-approval registry.
Gender:
All
Ages:
All
Trial Updated:
02/29/2024
Locations: Tampa General Hospital, Tampa, Florida
Conditions: Heart Transplant
Register for Updates
A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies
NCT04349436
Recruiting
This Phase 1B/2 study is a multicenter, open-label, study of RP1 to investigate the (a) objective response rate, in addition to (b) safety and tolerability of RP1 for the treatment of advanced cutaneous malignancies in up to 65 evaluable organ transplant recipients. This will include patients with either previous renal, hepatic, heart, lung, or other solid organ transplantation or hematopoietic cell transplant and experiencing subsequent documented locally advanced or metastatic cutaneous malign... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/28/2024
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Melanoma
Register for Updates