There are currently 980 clinical trials in Tampa, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Moffitt Cancer Center, University of South Florida, H. Lee Moffitt Cancer Center and Research Institute and Tampa General Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
DBT Skills Groups for Veterans at High Risk for Suicide Attempt
NCT05000749
Recruiting
Veteran suicide death is a national crisis. Risk factors include emotion dysregulation, which occurs across mental health disorders. Dialectical behavior therapy (DBT) is an evidence-based suicide intervention that targets emotion dysregulation but is resource-intensive and not widely available at VHA. A more efficient evidence-based DBT Skills Group (DBT-SG) is associated with reduced suicidal ideation and emotion dysregulation and likely more feasible to implement at VHA. This is a randomized... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/31/2023
Locations: James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida
Conditions: Suicide, Attempted
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Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067
NCT04787042
Recruiting
This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab [Gazyva®] pre-treatment, by IV infusion, and in combination with pembrolizumab. A Phase 2 monotherapy arm is also planned; the exact design of the Phase 2 study elements with respect to formulation and pre-treatment will be determined after completion of the Phase 1 study portion of the trial.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/30/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Cancer, Solid Tumor, Melanoma, Renal Cell Carcinoma, Triple-negative Breast Cancer, Non Small Cell Lung Cancer, Squamous Cell Carcinoma of the Head and Neck, Carcinoma, MSI-High
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Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer (VIKTORIA-1)
NCT05501886
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/30/2023
Locations: H. Lee Moffitt Cancer Center & Research Institute, Tampa, Florida
Conditions: Breast Cancer
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PMEG for Repair of Pararenal and Thoracoabdominal Aortic Aneurysm
NCT05195905
Recruiting
The primary objective is to evaluate the safety and effectiveness of surgeon modified endografts for the treatment of pararenal and thoracoabdominal aortic pathology in patients who are not candidate for traditional open repair due to comorbid issues and their anatomy is not amenable to commercially available endografts.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/25/2023
Locations: Tampa General Hospital, Tampa, Florida +1 locations
Conditions: Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
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Early Age-Related Hearing Loss Investigation Pilot Study
NCT05970211
Recruiting
The purpose of this clinical trial pilot is to obtain feasibility and pilot data necessary to inform the hearing intervention being designed for a larger R01 clinical trial that seeks to determine whether best practice hearing aid intervention impacts hearing-related outcomes in adults with hearing loss aged 55 to 75 years. Secondary purposes include: To determine what effects best practice hearing aid intervention has on physical, social, and quality of life outcomes in adults with hearing los... Read More
Gender:
All
Ages:
Between 55 years and 75 years
Trial Updated:
07/24/2023
Locations: University of South Florida, Tampa, Florida
Conditions: Hearing Loss
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Registry of Avance® Nerve Graft's Utilization and Recovery Outcomes Post Peripheral Nerve Reconstruction
NCT01526681
Recruiting
This study is a registry of general use of Avance Nerve Graft and is intended to evaluate the uses, response rates, and safety of Avance Nerve Graft in the real-life clinical setting. Optional addendums 1 and 2 included in the protocol are intended to establish comparative groups and focused subgroups within the registry.
Gender:
All
Ages:
All
Trial Updated:
07/17/2023
Locations: RANGER & MATCH: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Peripheral Nerve Injuries
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Non-Inferiority Trial of TrIGR for PTSD
NCT05789329
Recruiting
Trauma-related guilt is common and impairing among trauma survivors, particularly among Veterans with posttraumatic stress disorder (PTSD). The investigators' work shows that a brief treatment targeting trauma-related guilt, Trauma Informed Guilt Reduction Therapy (TrIGR), can reduce guilt and PTSD and depression symptoms. Whether TrIGR is no less effective than longer, more resource heavy PTSD treatments disseminated by by VA, like cognitive processing therapy (CPT), is the next critical questi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/13/2023
Locations: James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida
Conditions: PTSD
Register for Updates
Clinical Course of Alcohol Use Disorder Recovery
NCT05607290
Recruiting
The goal of this single-arm clinical trial is to better understand the ways in which individuals seeking treatment recover from Alcohol Use Disorder (AUD). The main aims are to: To establish operational definitions of types of change in relation to National Institute on Alcohol Abuse and Alcoholism's (NIAAA) new definition of recovery, and to distinguish between treatment response, remission versus recovery, and relapse versus recurrence. To describe patterns of recovery, including the frequenc... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: University of South Florida, Tampa, Florida
Conditions: Alcohol Use Disorder
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Optimal Treatment for Recurrent Clostridium Difficile
NCT02667418
Recruiting
The purpose of this study is to determine whether fidaxomicin and vancomycin followed by taper and pulse vancomycin treatment are superior to standard vancomycin treatment for the treatment of recurrent Clostridium difficile infection.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/07/2023
Locations: James A. Haley Veterans' Hospital, Tampa, FL, Tampa, Florida
Conditions: Clostridium, Difficile, Fidaxomicin, Vancomycin
Register for Updates
Timing of Active Void Trials After Urogynecologic Procedures
NCT05885958
Recruiting
The goal of this clinical trial is to learn about active void trial pass rates in patients undergoing urogynecologic surgery. The main question it aims to answer is the comparison in pass rate during active void trial between women who are given 30 minutes versus 60 minutes to void following urogynecologic surgery. Patient will be randomized to two arms prior to scheduled surgery. During the active void trial, women will be allotted up to 30 minutes or up to 60 minutes to void depending on resp... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/05/2023
Locations: USF Urogynecology Clinic, Tampa, Florida
Conditions: Postoperative Care, Urinary Catheters, Urogynecology
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Electromagnetic Fields Versus Placebo For Child-Pugh A and B Patients With Advanced Hepatocellular Carcinoma
NCT04797884
Recruiting
The primary goals of this study are to compare overall survival and quality of life in subjects with Child-Pugh A or B advanced hepatocellular carcinoma when treated with a device emitting radiofrequencies modulated at specific frequencies or with a device emitting unmodulated radiofrequencies.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/25/2023
Locations: Tampa General Hospital, Tampa General Cancer Center, Tampa, Florida
Conditions: Hepatocellular Carcinoma
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PRGN-3006 Adoptive Cellular Therapy for CD33-Positive Relapsed or Refractory AML, MRD Positive AML or Higher Risk MDS
NCT03927261
Recruiting
This is a first-in-human dose escalation/dose expansion study to evaluate the safety and identify the best dose of modified immune cells, PRGN-3006 (autologous chimeric antigen receptor (CAR) T cells), in adult patients with relapsed or refractory acute myeloid leukemia (AML), Minimal Residual Disease (MRD) positive acute myeloid leukemia or higher risk myelodysplastic syndrome (MDS). Autologous CAR T cells are modified immune cells that have been engineered in the laboratory to specifically tar... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/21/2023
Locations: H Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Conditions: Myelodysplastic Syndromes, Acute Myeloid Leukemia
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