There are currently 975 clinical trials in Tampa, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including Moffitt Cancer Center, University of South Florida, H. Lee Moffitt Cancer Center and Research Institute and Tampa General Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Apixaban for the Acute Treatment of Venous Thromboembolism in Children
NCT02464969
Recruiting
To assess the safety and descriptive efficacy of apixaban in pediatric subjects requiring anticoagulation for the treatment of a VTE.
Gender:
All
Ages:
Between 0 days and 17 years
Trial Updated:
02/06/2023
Locations: St. Joseph's Hospital, Tampa, Florida
Conditions: Venous Thromboembolism
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Efficacy and Safety of Plecanatide in Children 6 to <18 Years of Age With Irritable Bowel Syndrome With Constipation (IBS-C)
NCT03596905
Recruiting
This study of the efficacy and safety of Plecanatide in children 6 to <18 Years of Age with Irritable Bowel Syndrome with Constipation (IBS-C)
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
02/06/2023
Locations: Synergy Research Site, Tampa, Florida
Conditions: Irritable Bowel Syndrome With Constipation
Register for Updates
Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
NCT05369546
Recruiting
The objective is to better identify suspicious breast lesions that need to be biopsied for malignancy in women currently recommended for biopsy. The long-term goal is to reduce unnecessary biopsies and increase biopsy yield. To do this, the investigators have developed an innovative way to use FDA-approved breast imaging protocols to acquire multispectral images to measure the composition of suspicious breast lesions. The central hypothesis is that breast tissue composition in combination with a... Read More
Gender:
Female
Ages:
Between 20 years and 85 years
Trial Updated:
01/31/2023
Locations: H. Lee Moffitt Cancer Center & Research Institute, Inc., Tampa, Florida
Conditions: Breast Cancer
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A Study of Navicixizumab Monotherapy or in Combination in Patients With Select Advanced Solid Tumors
NCT05453825
Recruiting
This is a study of navicixizumab monotherapy or in combination with paclitaxel or irinotecan in patients with advanced cancer. Patients will be enrolled into one of the following cancer cohorts: Cohort A: CRC Cohort B: Gastric and GEJ cancer Cohort C: TNBC Cohort D: Platinum-resistant/refractory epithelial ovarian, primary peritoneal, or fallopian tube cancer (ovarian cancer)
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2023
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Colorectal Cancer, Triple Negative Breast Cancer, Gastric Cancer, Ovarian Cancer
Register for Updates
Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters
NCT05383274
Recruiting
Single-arm, prospective study assessing semen quality after treatment with the Optilume Urethral DCB in men between 22 and 65 years of age.
Gender:
Male
Ages:
Between 22 years and 65 years
Trial Updated:
01/26/2023
Locations: Florida Urology, Tampa, Florida
Conditions: Urethral Stricture
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A Study on the Immune Response and Safety of a Combined Measles, Mumps, Rubella, Chickenpox Vaccine Compared to a Marketed Combined Vaccine, Given to Healthy Children 4 to 6 Years of Age
NCT05630846
Recruiting
The main purpose of this study is to assess immune response and safety of various potencies of a measles, mumps, rubella, and varicella (MMRVNS) vaccines given to healthy children of 4 to 6 years of age.
Gender:
All
Ages:
Between 4 years and 6 years
Trial Updated:
01/16/2023
Locations: GSK Investigational Site, Tampa, Florida
Conditions: Measles; Mumps; Rubella; Chickenpox
Register for Updates
NBTXR3 With or Without Cetuximab in LA-HNSCC
NCT04892173
Recruiting
This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy/performance and safety of NBTXR3/RT±cetuximab versus RT±cetuximab in treatment-naïve, platinum-ineligible, elderly participants with LA-HNSCC.
Gender:
All
Ages:
65 years and above
Trial Updated:
12/28/2022
Locations: Lee Moffitt Cancer Center and Research Institute, Tampa, Florida
Conditions: Locally Advanced Head and Neck Squamous Cell Carcinoma, Aged
Register for Updates
A Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)
NCT02817633
Recruiting
This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022. The study will be conducted in 2 parts with Part 1 consisting of dose escalation and Part 2 dose expansion. Part 1 will determine the recommended Phase 2 dose (RP2D) of TSR-022 and Part 2 will evaluate the antitumor activity of TSR-022 in combination with TSR-042 or docetaxel and as monotherapy
Gender:
All
Ages:
18 years and above
Trial Updated:
12/09/2022
Locations: GSK Investigational Site, Tampa, Florida
Conditions: Neoplasms
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A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer
NCT03899636
Recruiting
Subjects will be offered the opportunity to participate in a randomized, controlled, 2-arm, unblinded multicenter trial (RCT). There will be 2 study arms: the control arm receiving chemotherapy with the modified FOLFIRINOX regimen alone; and the irreversible electroporation (IRE) arm, receiving chemotherapy with the modified FOLFIRINOX regimen followed by IRE with the NanoKnife System using either an open or a percutaneous approach. All subjects will be treated with the modified FOLFIRINOX regim... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/23/2022
Locations: University of South Florida/Tampa, Tampa, Florida
Conditions: Stage III Pancreatic Cancer
Register for Updates
Preventing Alzheimer's With Cognitive Training
NCT03848312
Recruiting
Dementia is the most expensive medical condition in the US and increases in prevalence with age. More than 5 million Americans have Alzheimer's disease, the most common form of dementia. Mild cognitive impairment is a transitional stage between normal cognitive aging and Alzheimer's disease or another type of dementia, and is indicative of higher risk for dementia. In addition to the obvious health and quality-of-life ramifications of dementia, there are high direct (e.g., subsidizing residentia... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
11/21/2022
Locations: University of South Florida, Tampa, Florida
Conditions: Age-related Cognitive Decline, Alzheimer's Disease and Related Dementias
Register for Updates
Trial of LAVA-1207 in Patients With Therapy Refractory Metastatic Castration Resistant Prostate Cancer
NCT05369000
Recruiting
This is a phase 1/2a, first-in-human study to evaluate the safety and tolerability of LAVA-1207 in patients with therapy refractory metastatic castration resistant prostate cancer
Gender:
Male
Ages:
18 years and above
Trial Updated:
11/18/2022
Locations: Moffitt Cancer Center, Tampa, Florida
Conditions: Metastatic Castration Resistant Prostate Cancer
Register for Updates
Dupilumab Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis
NCT04430179
Recruiting
The investigators will investigate the efficacy of dupilumab in patients with severe eosinophilic CRSsNP who are resistant to the conventional treatment with intranasal corticosteroids and have significantly extensive disease involving more than 2 sinuses bilaterally in sinus CT scan and Lund-Mackay sinus (LMK) CT score >=10 at baseline.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2022
Locations: University of South Florida Asthma, Allergy and Immunology, Tampa, Florida
Conditions: Severe Eosinophilic Chronic Sinusitis Without Nasal Polyposis
Register for Updates