The state of Georgia currently has 10 active clinical trials seeking participants for Autism research studies. These trials are conducted in various cities, including Atlanta, Augusta, Decatur and Savannah.
Early Diagnostic Response Model (EDRM)
Recruiting
Babies Can't Wait (BCW) in Georgia will be referring families with children seeking an autism spectrum disorder (autism) diagnosis at the Emory Autism Center's (EAC) Child Screening and Assessment Clinic.The objective of this study is to develop, pilot, and evaluate a diagnostic protocol for children identified at high risk for autism in the BCW early intervention program screening (part of a public health service). This program evaluation will be using pre- and post-data and data collected thro... Read More
Gender:
All
Ages:
Between 16 months and 36 months
Trial Updated:
03/22/2024
Locations: Emory Autism Center, Atlanta, Georgia
Conditions: Autism Spectrum Disorder, Autism
Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder
Recruiting
The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish the benefit-risk profile of long-term treatment in this population.
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
03/04/2024
Locations: Atlanta Center for Medical Research /ID# 234698, Atlanta, Georgia +2 locations
Conditions: Schizophrenia, Bipolar I Disorder, Autism Spectrum Disorder (ASD)
Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD
Recruiting
Autism spectrum disorder (ASD) consists of deficits in social, communication, and cognitive development, repetitive and stereotypic behaviors. Many ASD patients show notably high levels of irritability, including verbal and physical aggression, self injury, and/or property destruction. Autistic infants tend to avoid eye contact and show little interest in others. This study will assess how safe and effective cariprazine is in treating pediatric participants (5 to 17 years of age) with ASD. Adver... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
02/23/2024
Locations: Atlanta Center for Medical Research /ID# 243124, Atlanta, Georgia +2 locations
Conditions: Autism Spectrum Disorder
Treatment Monitoring in Autism Spectrum Disorder (ASD) in Children
Recruiting
The goal of this clinical study is to learn about the utility and performance of the EarliPoint(™) System: Evaluation for Autism Spectrum Disorder to monitor changes in a child's verbal ability, non-verbal learning, and social disability over time in children ages 15-84 months with autism spectrum disorder or related developmental delays (DD) and in those who are typically developing. The main questions it aims to answer are: To estimate the change in each of the EarliPoint index scores in typ... Read More
Gender:
All
Ages:
Between 15 months and 84 months
Trial Updated:
02/02/2024
Locations: Emory University/Marcus Autism Center, Atlanta, Georgia
Conditions: Autism Spectrum Disorder, Autism, Developmental Delay, Autism, Early Infantile, Autism, Infantile
Peer Interventions for Preschoolers With Autism
Recruiting
This proposal will evaluate a series of peer-mediated interventions (PMIs) for preschool children (3 to 6 years) with ASD and limited or no spoken language, using an innovative Sequential Multiple Assignment Randomized Trial (SMART) design. Available evidence supports the beneficial effects of PMIs for improving social communication in children with ASD. Peer-related social competence is vital to a wide range of child outcomes, such as improved communication and fewer behavioral problems. Unfort... Read More
Gender:
All
Ages:
Between 3 years and 6 years
Trial Updated:
12/18/2023
Locations: Early Emory Center for Child Development, Decatur, Georgia
Conditions: Autism Spectrum Disorder
Leucovorin for the Treatment of Language Impairment in Children With Autism Spectrum Disorder
Recruiting
The purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder. Folinic acid, also known as leucovorin, is approved by the U.S. Food and Drug Administration (FDA) to decrease side effects during cancer chemotherapy. Folinic acid may be helpful in treating language problems in children with autism spectrum disorder, but this is not known. Therefore, folinic acid is an investigational new drug for this stu... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
10/23/2023
Locations: Children's Healtcare of Atlanta, Atlanta, Georgia
Conditions: Autism Spectrum Disorder
Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort
Recruiting
The purpose of this research use only (RUO) study is to detect genomic structural variants (SVs) in human DNA by Optical Genome Mapping (OGM) using the Bionano Genomics Saphyr system. SVs are a type of genetic alternation that includes deletions, duplications, and both balanced and unbalanced rearrangements (ex: inversions or translocations), as well as specific repeat expansions and contractions. The results of OGM analysis will be compared to prior clinical genetic test results to determine ho... Read More
Gender:
All
Ages:
All
Trial Updated:
08/04/2023
Locations: Praxis Genomics, Atlanta, Georgia +1 locations
Conditions: Developmental Disability, Intellectual Disability, Autism Spectrum Disorder, Congenital Anomaly, Fragile X Syndrome, Facioscapulohumeral Muscular Dystrophy 1
Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care
Recruiting
The goal of this collaborative R01 is to demonstrate the therapeutic value and community-wide implementability of an early intervention (EI) platform for toddlers with autism spectrum disorder (ASD) that is completely virtual, from recruitment through intervention. This platform-Early Social Interaction Mobile Coaching (ESI-MC) deploys individual telehealth sessions with coaching and feedback to help families embed intervention in everyday activities. Specifically, the investigators will conduct... Read More
Gender:
All
Ages:
Between 15 months and 20 months
Trial Updated:
06/21/2023
Locations: Emory University, Atlanta, Georgia
Conditions: Autism Spectrum Disorder
Screening for Autism in 9-Month-Olds by Measuring Social Visual Engagement
Recruiting
The goal of this project is to measure the clinical utility of an objective and quantitative eye-tracking assay collected on a standalone, mobile investigational device to accurately screen 9-month-old infants for autism spectrum disorder and other actionable delays.
Gender:
All
Ages:
Between 8 months and 10 months
Trial Updated:
06/14/2023
Locations: Children's Healthcare of Altanta, Atlanta, Georgia +1 locations
Conditions: Autism, Infant Development
Validation of a Salivary miRNA Diagnostic Test for ASD
Recruiting
This study involves sample collection to identify biomarkers relating to Autism Spectrum Disorder(ASD) in the saliva of children who are between the ages of 18 months to 6 years and 11 months. Participants will at each timepoint have a non-invasive saliva swab collected and complete a brief demographic and medical history questionnaire as well. Children in the pediatric/provider setting who will receive a referral for an ASD diagnosis because they were determined to have a suspicion of developin... Read More
Gender:
All
Ages:
Between 18 months and 7 years
Trial Updated:
02/06/2023
Locations: Marcus Autism Center/Emory University, Atlanta, Georgia
Conditions: Autism Spectrum Disorder, Developmental Delay