The state of Illinois currently has 51 active clinical trials seeking participants for Arthritis research studies. These trials are conducted in various cities, including Chicago, Peoria, Springfield and Urbana.
Tc 99m Tilmanocept Imaging for Early Prediction of Anti-TNFα Therapy Response in Moderate to Severe Active RA
Recruiting
This study will confirm the ability of Tc 99m tilmanocept imaging to predict clinical response in individuals with RA who are beginning anti-TNFα therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/31/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Rheumatoid Arthritis
Study of Nonsteroidal Anti-inflammatory Drugs in People With Painful Knee Osteoarthritis
Recruiting
This is a pilot study with a 4-period double-cross-over design evaluating a treatment with non-steroidal anti-inflammatory drugs (NSAIDs) in people with painful knee osteoarthritis.
Gender:
All
Ages:
40 years and above
Trial Updated:
10/25/2023
Locations: Northwestern University Feinberg School of Medicine, Chicago, Illinois
Conditions: Osteoarthritis, Knee
Efficacy of Intra-articular Injections for the Treatment of Primary Glenohumeral Osteoarthritis(GHOA)
Recruiting
The purpose of this study is to compare the efficacy of intra-articular corticosteroid injections versus platelet-rich plasma injections for non-operative treatment of primary glenohumeral osteoarthritis. The efficacy of intra-articular injections, outside of hyaluronic acid, for the treatment of glenohumeral OA is not known, yet these treatments are commonly used with hopes of providing patients with symptomatic relief that can hopefully delay or prevent the need for shoulder arthroplasty. This... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/25/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Arthritis Shoulder
A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
Recruiting
RENOIR Study: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe Rheumatoid Arthritis (RA)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2023
Locations: Anaptys Bio Investigative Site 10-114, Chicago, Illinois
Conditions: Rheumatoid Arthritis
Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
Recruiting
An open-label, single-arm clinical trial to confirm the safety of monoarticular injections or bi-lateral intra-articular injections of RTX-GRT7039 in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Chicago Clinical Research Institute Inc., Chicago, Illinois
Conditions: Osteoarthritis
Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection
Recruiting
Prospective single-masked (study participant will be masked), randomized controlled trial to examine the influence of BMAC on patient-reported outcomes (PROs) in patients with primary knee osteoarthritis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/02/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Osteoarthritis of the Knee
Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb
Recruiting
Thumb carpometacarpal (CMC) osteoarthritis (OA) is common, seen frequently in middle-aged and elderly women. While a variety of surgical treatments have been described with none superior to any other, there is no consensus on the optimal duration of postoperative immobilization. Immobilization following surgery is critical for wound healing, pain control, and aid with activities of daily living in the early recovery period, though the duration of this must be weighed against the negative impacts... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
06/01/2023
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Thumb Osteoarthritis
The Impact of a Seated Compact Elliptical Trainer on Individuals With Knee OA
Recruiting
Exercise is considered the most effective, non-drug treatment for reducing pain and improving movement in patients with osteoarthritis. Diminished muscle strength is a common symptom associated with the onset of knee osteoarthritis. The evidence supports the benefit of exercise therapy, in reducing pain and improving function in subjects with knee OA, however research to date has been unable to quantify the disease-modifying effect of any form of exercise. The primary objective of this study is... Read More
Gender:
All
Ages:
Between 50 years and 75 years
Trial Updated:
05/11/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Impact of Different Exercise Programs on Knee OA
Recruiting
This study will examine and compare the changes in serum biomarkers, joint kinematics, and thigh muscle strength based on three different 8-week exercise protocols in individuals with knee pathology: Lower-body positive-pressure (LBPP) supported low-load treadmill walking and Aquatic exercise program and standard of care treadmill or community walking. Investigators hypothesize that both the 8-week exercise programs which aim to partially off-load the knee joint will be associated with a signif... Read More
Gender:
All
Ages:
Between 50 years and 75 years
Trial Updated:
05/02/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Osteoarthritis, Knee Osteoarthritis, Arthritis, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
Comparison of Tc 99m Tilmanocept Quantitative Imaging With Immunohistochemical (IHC) Analysis of CD206 Expression in Synovial Tissue of Subjects With Rheumatoid Arthritis (RA)
Recruiting
This study is a comparison of quantitative Tc 99m tilmanocept imaging with IHC analysis of CD206 expression in synovial tissue of RA subjects.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2023
Locations: Northwestern University, Chicago, Illinois
Conditions: Rheumatoid Arthritis
Physica System Total Knee Replacement Registry Study
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: Rush Castle Orthopaedics, Aurora, Illinois
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
Impact of Sensor Technology in Knee OA
Recruiting
OBJECTIVES: Physical activity has been established as an important component of rehabilitation for knee osteoarthritis (OA), and is often guided by a physical therapist.(1) Physical therapy for knee OA typically involves 1-3 sessions with a licensed physical therapist per week, for up to 12 weeks. These sessions can take a lot of time and effort for subjects, particularly when travel times are considered. Remote patient monitoring is an emerging treatment method which can help to reduce the nee... Read More
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
01/24/2022
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Knee Osteoarthritis