The state of Illinois currently has 12 active clinical trials seeking participants for Autism research studies. These trials are conducted in various cities, including Chicago, Peoria, Springfield and Urbana.
Effectiveness Trial of Mobile ESI for Toddlers With Autism Identified by Early Screening in Primary Care
Recruiting
The goal of this collaborative R01 is to demonstrate the therapeutic value and community-wide implementability of an early intervention (EI) platform for toddlers with autism spectrum disorder (ASD) that is completely virtual, from recruitment through intervention. This platform-Early Social Interaction Mobile Coaching (ESI-MC) deploys individual telehealth sessions with coaching and feedback to help families embed intervention in everyday activities. Specifically, the investigators will conduct... Read More
Gender:
All
Ages:
Between 15 months and 20 months
Trial Updated:
05/15/2024
Locations: Rush University, Chicago, Illinois
Conditions: Autism Spectrum Disorder
Pimavanserin for the Treatment of Irritability Associated With Autism Spectrum Disorder
Recruiting
6-week, randomized, double-blind, fixed-dose, placebo-controlled, parallel group study in children and adolescents (aged 5 to17 years) with autism spectrum disorder (ASD) with irritability, agitation, or self-injurious behaviors to study the efficacy and safety of pimavanserin
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
05/08/2024
Locations: AMR Baber Research Incorporated, Naperville, Illinois
Conditions: Irritability Associated With Autism Spectrum Disorder
Extension Study of Pimavanserin in Irritability Associated With Autism Spectrum Disorder
Recruiting
52-week, open-label extension study of double-blind study ACP-103-069 to determine the long-term safety and tolerability of pimavanserin for the treatment of irritability associated with ASD in children and adolescents (aged 5 to 17 years). ACP-103-069 is a 6-week, randomized, double-blind, fixed-dose, placebo controlled, parallel group study of pimavanserin in children and adolescents with irritability associated with autism spectrum disorder (ASD).
Gender:
All
Ages:
Between 5 years and 18 years
Trial Updated:
05/02/2024
Locations: AMR Baber Research Incorporated, Naperville, Illinois
Conditions: Irritability Associated With Autism Spectrum Disorder
ML-004 in Adolescents and Adults With Autism Spectrum Disorders (ASD)
Recruiting
ML-004-002 is a multi-center, randomized, double-blind, parallel-group, placebo-controlled study that will enroll approximately 150 adolescent and adult subjects with ASD. The primary objective is to evaluate the efficacy of ML-004 compared with placebo in the improvement of social communication deficits in subjects with ASD.
Gender:
All
Ages:
Between 12 years and 45 years
Trial Updated:
04/30/2024
Locations: AMR-Baber Research Inc, Naperville, Illinois
Conditions: Autism Spectrum Disorder
Open-Label, Flexible-dose Study to Evaluate the Long-Term Safety and Tolerability of Cariprazine in the Treatment of Pediatric Participants With Schizophrenia, Bipolar I Disorder, or Autism Spectrum Disorder
Recruiting
The purpose of this study is to evaluate the long-term safety and tolerability of cariprazine in the treatment of pediatric participants with schizophrenia, bipolar I disorder, or autism spectrum disorder (ASD) and to establish the benefit-risk profile of long-term treatment in this population.
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
03/04/2024
Locations: Ascension St. Elizabeth /ID# 235857, Chicago, Illinois
Conditions: Schizophrenia, Bipolar I Disorder, Autism Spectrum Disorder (ASD)
International Multicentric Observational Study to Characterize Subpopulations of Patients With Autism Spectrum Disorder
Recruiting
To determine sufficient number of biological and clinical markers to identify subgroups of potential best responders to a specific medication
Gender:
All
Ages:
Between 12 years and 65 years
Trial Updated:
03/01/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Autism Spectrum Disorder
Testing a Family Service Navigator Program for Low-resourced Families of Young Children With Autism Spectrum Disorder
Recruiting
The purpose of this study is to develop and test a family navigator training and an app (a technology-based treatment support system) for low-resourced families of young children (aged 3-5) with autism. The hypothesis is that the navigator training and treatment support system will help enable navigators to support families of young children with autism in accessing needed services.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/06/2024
Locations: University of Illinois at Urbana-Champaign, Champaign, Illinois
Conditions: Autism Spectrum Disorder, Mental Health Services
Mapping the Genotype, Phenotype, and Natural History of Phelan-McDermid Syndrome
Recruiting
The purpose of this study is to comprehensively characterize PMS using standardized medical, cognitive, and behavioral measures and to track the natural history of the syndrome using repeated longitudinal assessments. In addition, this study will be aiming to identify biomarkers using neuroimaging, including diffusion tensor imaging and identify genetic factors which contribute to diverse phenotypes in patients with PMS.
Gender:
All
Ages:
18 months and above
Trial Updated:
11/09/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Phelan-McDermid Syndrome, Autism Spectrum Disorder, Intellectual Disability
Optimizing Outcomes for Young Autistic Children
Recruiting
The overarching goal of the proposed study is to: (a) determine how best to sequence two parent-mediated interventions: a social communication intervention (Project ImPACT, Improving Parents as Communication Teachers) and a disruptive behavior intervention (Parent Training for Disruptive Behavior) and (b) examine moderators and mediators of intervention outcomes.
Gender:
All
Ages:
Between 18 months and 48 months
Trial Updated:
07/18/2023
Locations: Northwestern University, Evanston, Illinois
Conditions: Autism, Autism Spectrum Disorder
Impact of Sulphonylureas on Neurodevelopmental Outcomes in KCNJ11-related Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome
Recruiting
The goal of this observational study is to learn about the impact of the diabetes drug glibenclamide (glyburide) on neurodevelopment in individuals with iDEND (developmental delay, epilepsy and neonatal diabetes) due to the V59M mutation in the KCNJ11 gene. The main question it aims to answer is whether initiating sulphonylurea (SU) therapy in the first 6 months of life results in better neurodevelopmental outcomes in affected individuals, in comparison to starting therapy later than 6 months of... Read More
Gender:
All
Ages:
Between 2 years and 50 years
Trial Updated:
02/20/2023
Locations: University of Chicago, Chicago, Illinois
Conditions: Neurodevelopmental Disorders, Intellectual Disability, Development Delay, ADHD, Autism Spectrum Disorder, Epilepsy
Validation of a Salivary miRNA Diagnostic Test for ASD
Recruiting
This study involves sample collection to identify biomarkers relating to Autism Spectrum Disorder(ASD) in the saliva of children who are between the ages of 18 months to 6 years and 11 months. Participants will at each timepoint have a non-invasive saliva swab collected and complete a brief demographic and medical history questionnaire as well. Children in the pediatric/provider setting who will receive a referral for an ASD diagnosis because they were determined to have a suspicion of developin... Read More
Gender:
All
Ages:
Between 18 months and 7 years
Trial Updated:
02/06/2023
Locations: RUSH University, Chicago, Illinois
Conditions: Autism Spectrum Disorder, Developmental Delay
Improving the Part C Early Intervention Service Delivery System for Children With ASD
Recruiting
Despite strong consensus that early, specialized intervention for children with Autism Spectrum Disorder (ASD) can have a dramatic impact on outcomes, the public health system's capacity to provide such services is severely challenged by the rapid rise in ASD prevalence. The goal of this research project is to increase timely and equitable access to ASD-specialized early intervention during the critical first three years of life by capitalizing on the existing infrastructure of the Part C Early... Read More
Gender:
All
Ages:
Between 16 months and 30 months
Trial Updated:
01/27/2023
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Autism Spectrum Disorder