The state of Indiana currently has 17 active clinical trials seeking participants for Asthma research studies. These trials are conducted in various cities, including Indianapolis, South Bend, Fort Wayne and Evansville.
A Study to Evaluate Solriktug in Adult Participants With Asthma
Recruiting
Phase 2 study to evaluate the safety, tolerability, PK, immunogenicity, and pharmacodynamics of solriktug with adult participants with asthma.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/23/2024
Locations: Research Site 019, Merrillville, Indiana
Conditions: Asthma
Developing a Childhood Asthma Risk Passive Digital Marker
Recruiting
Underdiagnosis and undertreatment is a major problem in childhood asthma management, especially in preschool-aged children. Current prognostic approaches using risk-score based tools have poor-to-modest accuracy, are impractical, and have limited evidence of efficacy in clinical settings and hence are not widely used in practice. The objective of the study is to determine the usability, acceptability, feasibility, and preliminary efficacy of the childhood asthma passive digital marker (PDM) amo... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/23/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Pediatric Asthma
Inspiratory Muscle Training on The Severity of Exercise-Induced Bronchoconstriction and Time-Trial Performance (IMT_EIB)
Recruiting
Due to the lack of studies examining the impact of inspiratory muscle training (IMT) on the severity of exercise-induced bronchoconstriction (EIB) and exercise performance, the specific aim of this study is to assess the efficacy of flow-resistive IMT on EIB severity and symptoms, short-acting beta-2-agonist medication use, operating lung volumes, respiratory and limb locomotor muscle deoxygenation during constant-load cycling exercise, exertional dyspnea, and cycling time-trial performance.
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
03/27/2024
Locations: School of Public Health-Bloomington, Bloomington, Indiana
Conditions: Exercise Induced Bronchospasm, Exercise Induced Asthma
Project 2 Airway Potential Hydrogen (pH) in Asthma
Recruiting
This study is testing a non invasive way to measure airway pH in individuals with Asthma and Cystic Fibrosis using a new inhaled drug. The airway pH will help health care providers in creating tailored treatment plans for individuals suffering from these specific conditions.
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
03/13/2024
Locations: Indiana University School of Medicine, Indianapolis, Indiana
Conditions: Cystic Fibrosis, Asthma, Severe Persistent Asthma, Healthy
5HTP Regulation Of Asthma In Children
Recruiting
The purpose of this study is to learn more about if taking a supplement called 5-hydroxytryptophan (5HTP) can improve breathing and anxiety symptoms related to asthma. To help learn more subjects will either be assigned to a group that is taking the supplement (5HTP) or a group that is taking a placebo. This will be decided randomly. Later in the study subjects will crossover to the other group.There are 5 study visits over the course of about 12 weeks.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
02/26/2024
Locations: Indiana University, Indianapolis, Indiana
Conditions: Mild or Moderate Asthma With Allergic Sensitization