The state of Kansas currently has 6 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Wichita, Kansas City, Overland Park and Topeka.
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/22/2025
Locations: Cotton O'Neil Clinical Research Center - Central Office, Topeka, Kansas
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
INJECTABLE COLD ENERGY THERAPY FOR THE MANAGEMENT OF CHRONIC PAIN ASSOCIATED WITH OSTEOARTHRITIS OF THE KNEE
Recruiting
The goal of this clinical trial is to evaluate the effectiveness of Neural Ice for pain management associated with knee osteoarthritis in adults aged 22-80 years. Participants will attend study visits and complete subject diaries. Participants will be followed for 6 months after study procedure.
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
05/21/2025
Locations: NextStage Clinical Research Advanced Orthopaedic Associates, Wichita, Kansas
Conditions: Osteoarthritis (OA) of the Knee
ZILRETTA in Subjects With Shoulder Osteoarthritis
Recruiting
Primary Objective: To assess the efficacy of ZILRETTA on pain following an intra-articular (IA) injection in subjects with glenohumeral osteoarthritis (OA) relative to normal saline placebo Secondary Objective: * To assess the efficacy of ZILRETTA on pain following an IA injection in subjects with glenohumeral OA relative to triamcinolone acetonide injectable suspension, immediate release (TCA-IR) and normal saline placebo * To assess the safety of ZILRETTA in subjects with glenohumeral OA rel... Read More
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
05/19/2025
Locations: Kansas City Bone & Joint Clinic - Overland Park, Overland Park, Kansas
Conditions: Glenohumeral Osteoarthritis
53-Week Study Evaluating the Safety and Efficacy of Intra-articular Injections of TPX-100 With Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
Recruiting
53-Week Study Evaluating the Safety and Efficacy of Intra-articular (IA) Injections of TPX-100 vs Placebo in Subjects with Mild to Severe Tibio-Femoral Osteoarthritis of the Knee
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
05/09/2025
Locations: AMR Kansas City, Kansas City, Kansas +1 locations
Conditions: Osteoarthritis (OA) of the Knee
Knee Osteoarthritis Treatment with Zilretta Vs. Kenalog in the Context of Type II Diabetes
Recruiting
A Phase 2 Randomized Study to Evaluate the Effects of triamcinolone acetonide extended-release (TA-ER; Zilretta) vs. triamcinolone acetonide immediate-release (TA-IR; Kenalog) on Blood Glucose Levels in Diabetic Subjects with Knee Osteoarthritis. Subjects should have Type 2 Diabetes Mellitus (T2DM) with HbA1C ≤9 that is managed without insulin and have been diagnosed with symptomatic unilateral or bilateral osteoarthritis (OA) of the knee, based on clinical and radiological criteria (if bilatera... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
09/17/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Osteoarthritis, Knee, Diabetes Mellitus, Type 2
Knee Arthroplasty Activity Trial
Recruiting
Total knee replacement (TKR) is a common and costly procedure widely used to relieve pain and improve function in patients with symptomatic advanced knee osteoarthritis (OA). As of 2013, the annual incidence of TKR was over 680,000 surgeries and annual costs exceeded $11 billion. Growing evidence suggests that while pain and functional status improve following TKR, physical activity (PA) typically does not surpass pre-TKR levels. Engagement in PA can meaningfully improve quality of life (QoL), p... Read More
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
04/15/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Knee Osteoarthritis, Total Knee Replacement