There are currently 632 clinical trials in Louisville, Kentucky looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Louisville, Jewish Hospital, Norton Cancer Institute and Saints Mary and Elizabeth Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
All
Ages:
15 months and below
Trial Updated:
05/01/2024
Locations: Norton Children's Hospital, Louisville, Kentucky
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
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Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus
NCT05561114
Recruiting
To evaluate the safety and efficacy of the ProTractX3™ DCB for the treatment of benign esophageal strictures.
Gender:
All
Ages:
22 years and above
Trial Updated:
04/30/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Esophageal Stricture
Register for Updates
A Study of Danavorexton in People With Obstructive Sleep Apnea After General Anesthesia for Abdominal Surgery
NCT05814016
Recruiting
The main aim is to see if danavorexton can help improve people's breathing in the recovery room after abdominal surgery.
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
04/30/2024
Locations: University of Louisville - Hospital, Louisville, Kentucky
Conditions: Sleep Apnea
Register for Updates
Study of CYR-064 Versus Placebo in Patients.
NCT06019000
Recruiting
Randomized, double-blinded, placebo-controlled trial to determine the safety and efficacy of CYR-064.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/30/2024
Locations: Kentuckian ENT, Louisville, Kentucky +1 locations
Conditions: Hyposmia
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Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)
NCT05153239
Recruiting
Multicenter, open-label, randomized, controlled phase III clinical trial to evaluate and compare the activity and safety of two experimental arms consisting of lurbinectedin as single agent (Group A) or the combination of lurbinectedin with irinotecan (Group B) versus Investigator's Choice (topotecan or irinotecan) as control arm (Group C), in Small-cell Lung Cancer (SCLC) patients who failed one prior platinum-containing line.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Norton Cancer Institue, Downtown, Louisville, Kentucky
Conditions: Relapsed Small Cell Lung Cancer
Register for Updates
Neoadjuvant Combination Immunotherapy for Stage III Melanoma
NCT03842943
Recruiting
Determine safety and efficacy of pre-operative combination immunotherapy with Talimogene Laherparepvec (T-VEC)/Pembrolizumab given prior to complete lymph node dissection in resectable stage 3 cutaneous melanoma with clinically apparent lymph node metastases.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Cutaneous Melanoma
Register for Updates
Phase I/IIa Study for AZD5335 as Monotherapy and in Combination With Anti-cancer Agents in Participants With Solid Tumors
NCT05797168
Recruiting
This research is designed to determine if experimental treatment with Antibody-drug conjugate, AZD5335, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced tumors
Gender:
All
Ages:
Between 18 years and 130 years
Trial Updated:
04/30/2024
Locations: Research Site, Louisville, Kentucky
Conditions: Ovarian Cancer, Lung Adenocarcinoma
Register for Updates
Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Baptist Health Systems, Inc., DBA Baptist, Louisville, Kentucky
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
Register for Updates
Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Bowel
NCT05561127
Recruiting
To determine the safety and efficacy of GIE Medical's ProTractX3™ TTS DCB for the treatment of recurrent benign bowel strictures.
Gender:
All
Ages:
22 years and above
Trial Updated:
04/30/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Bowel; Stricture
Register for Updates
This Study Aims to Find the Best Dose of BI 907828 (Brigimadlin) in Patients With Different Types of Advanced Cancer (Solid Tumors)
NCT03449381
Recruiting
This study is open to adults with different types of advanced cancer (solid tumors). The purpose of this study is to find out the most suitable dose of BI 907828 (brigimadlin) the participants can tolerate. The most suitable dose is used in the second part to find out whether brigimadlin makes tumors shrink. In this study, brigimadlin is given to humans for the first time. Brigimadlin is a so-called MDM2 inhibitor that is being developed to treat cancer. Brigimadlin is taken as a tablet. Partic... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Norton Cancer Institute, Downtown, Louisville, Kentucky
Conditions: Neoplasms
Register for Updates
PF-06821497 Treatment Of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma
NCT03460977
Recruiting
A Phase 1 Dose Escalation and Expanded Cohort Study Of PF-06821497 In The Treatment Of Adult Patients With Relapsed/Refractory Small Cell Lung Cancer (SCLC), Castration Resistant Prostate Cancer (CRPC) And Follicular Lymphoma (FL).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: Norton Cancer Institute Pharmacy, Downtown Pharmacy, Louisville, Kentucky +3 locations
Conditions: Small Cell Lung Cancer (SCLC), Follicular Lymphoma (FL), Castration Resistant Prostate Cancer (CRPC)
Register for Updates
The Ailliance Post-Market Clinical Study
NCT05856370
Recruiting
The purpose of this clinical study is to collect performance and safety data for post-market Medtronic devices indicated for cranial and/or spinal indication(s). Subjects are enrolled and followed postoperatively for up to 24 months. The Ailliance clinical study is intended to collect data congruous with routine clinical care practices.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/26/2024
Locations: Norton Leatherman Spine Specialists, Louisville, Kentucky
Conditions: Spinal Deformity, Spinal Degenerative Disorder, Spinal Fusion Failure, Spinal Trauma, Spinal Tumor Case
Register for Updates