The city of Baltimore, Maryland, currently has 6 active clinical trials seeking participants for Epilepsy research studies.
Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
Recruiting
The purpose of this study is to determine whether BHV-7000 is effective in the treatment of refractory focal epilepsy.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/19/2025
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Focal Epilepsy
AMT-260 Gene Therapy Study in Adults with Unilateral Refractory Mesial Temporal Lobe Epilepsy
Recruiting
This is a study of AMT-260 in Adults with Unilateral Refractory Mesial Temporal Lobe Epilepsy (MTLE). It is designed to investigate the Safety, Tolerability, and Efficacy of AMT-260 in Adults with MTLE Administered via Magnetic Resonance Imaging (MRI)-guided Convection-enhanced Delivery (CED).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/27/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Mesial Temporal Lobe Epilepsy
Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
ALL
Ages:
9 years and above
Trial Updated:
11/14/2024
Locations: Sinai Hospital, Baltimore, Maryland +1 locations
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
Ketogenic Diet for New-Onset Absence Epilepsy
Recruiting
The ketogenic diet is a medical therapy for epilepsy that is used nearly predominantly for refractory epilepsy (after 2-3 drugs have been tried and failed). However, there is both published evidence for first-line use (infantile spasms, Glut1 deficiency syndrome) and also anecdotal experience (families choosing to change the child's (or the family' own) diet rather than use anticonvulsant medications). Childhood absence epilepsy (refractory) has been published as being responsive to ketogenic di... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
08/05/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Absence Epilepsy, Ketogenic Dieting, Epilepsy, Absence
Epidiolex® for Anxiety in Pediatric Epilepsy
Recruiting
This is a prospective open label study assessing the efficacy and tolerability of pharmaceutical grade cannabidiol--Epidiolex (R), for the treatment of anxiety in pediatric patients with pediatric epilepsy that has been difficult to treat and requires ongoing use of anticonvulsant medication.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
05/22/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Anxiety, Epilepsy
Effects of Recorded Music on Clinical and EEG Seizure Activity
Recruiting
This research is being done to determine if Mozart music and/or age-appropriate music can reduce the frequency of seizures and epileptiform discharges.
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
03/18/2024
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Epilepsy