The city of Baltimore, Maryland, currently has 6 active clinical trials seeking participants for Epilepsy research studies.
AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy
NCT06063850
Recruiting
The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mesial temporal lobe epilepsy (MTLE).
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/12/2025
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Mesial Temporal Lobe Epilepsy
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Study to Determine if BHV-7000 is Effective and Safe in Adults With Refractory Focal Onset Epilepsy
NCT06309966
Recruiting
The purpose of this study is to determine whether BHV-7000 is effective in the treatment of refractory focal epilepsy.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/07/2025
Locations: Johns Hopkins University, Baltimore, Maryland
Conditions: Focal Epilepsy
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Effects of Recorded Music on Clinical and EEG Seizure Activity
NCT05289934
Recruiting
This research is being done to determine if Mozart music and/or age-appropriate music can reduce the frequency of seizures and epileptiform discharges.
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
03/05/2025
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Epilepsy
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Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
NCT04770337
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
ALL
Ages:
9 years and above
Trial Updated:
11/14/2024
Locations: Sinai Hospital, Baltimore, Maryland +1 locations
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
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Ketogenic Diet for New-Onset Absence Epilepsy
NCT04274179
Recruiting
The ketogenic diet is a medical therapy for epilepsy that is used nearly predominantly for refractory epilepsy (after 2-3 drugs have been tried and failed). However, there is both published evidence for first-line use (infantile spasms, Glut1 deficiency syndrome) and also anecdotal experience (families choosing to change the child's (or the family' own) diet rather than use anticonvulsant medications). Childhood absence epilepsy (refractory) has been published as being responsive to ketogenic di... Read More
Gender:
ALL
Ages:
Between 3 years and 12 years
Trial Updated:
08/05/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Absence Epilepsy, Ketogenic Dieting, Epilepsy, Absence
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Epidiolex® for Anxiety in Pediatric Epilepsy
NCT05324449
Recruiting
This is a prospective open label study assessing the efficacy and tolerability of pharmaceutical grade cannabidiol--Epidiolex (R), for the treatment of anxiety in pediatric patients with pediatric epilepsy that has been difficult to treat and requires ongoing use of anticonvulsant medication.
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
05/22/2024
Locations: Kennedy Krieger Institute, Baltimore, Maryland
Conditions: Anxiety, Epilepsy
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