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Pain Paid Clinical Trials in Maryland
A listing of 59 Pain clinical trials in Maryland actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 59
The state of Maryland currently has 59 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Baltimore, Bethesda, Rockville and Annapolis.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Recruiting
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
State-dependent Interoception, Value-based Decision-making, and Introspection
Recruiting
Background:
Negative emotional states can affect a person s behavior as they make decisions. For example, hunger may make people more impatient; they may then make riskier choices. Other negative emotional states that can change behavior include stress, pain, and sadness. By learning more about how emotions affect thinking and behavior in healthy people, researchers hope to better understand how to identify and treat people with mental disorders.
Objective:
To learn how negative emotions affe... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/10/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Stress, Pain, Emotions, Craving, Frustration
Randomized Blinded Evaluation of the Effects of TENS and IFC Compared to a Sham Device and SOC in Patients With Non-Specific CLBP
Recruiting
This is a prospective, sham-controlled, randomized, single-blinded, multi-center study comparing two different modes of the NexWave device, transcutaneous electrical nerve stimulation (TENS) and interferential current (IFC), with an identical non-functioning NexWave sham device or self-defined standard of care for improvement of pain intensity of non-specific CLBP.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
07/09/2025
Locations: CAO Research Foundation, Catonsville, Maryland
Conditions: Non-Specific Chronic Lower Back Pain
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Pain and Spine Specialist of Maryland, Mount Airy, Maryland
Conditions: Chronic Pain
Clinical Utility of Neurophysiological Measurements of ECAP-controlled Closed-loop SCS to Guide Treatment of Chronic Pain
Recruiting
The purpose of this study is to evaluate the clinical utility of neurophysiological measurements of ECAP-controlled closed-loop SCS (i.e., neural panel metrics) to guide treatment of chronic pain of the trunk and/or limbs.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Spine and Joint Institute, Glen Burnie, Maryland
Conditions: Chronic Pain
Pain Self-Management and Patient-Oriented Dosing for Pain and in Retention Opioid Treatment
Recruiting
This study seeks to improve the treatment of chronic pain in people who are taking buprenorphine (also known as Suboxone, Subutex, Zubsolv).
The research study is testing two different interventions along with usual clinical care:
1. Pain Self-Management (PSM): an educational program in which individuals with chronic pain work with a trained pain coach and a pain peer to explore strategies to effectively manage the daily problems that arise from chronic pain.
2. Patient-Oriented Dosing (POD):... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/03/2025
Locations: Alcohol and Drug Abuse Program (ADAP) - UM Addiction Treatment Center, Baltimore, Maryland +2 locations
Conditions: Opioid Use Disorder, Chronic Pain
Muscle Strength Loss and Its Effect on Knee Cap Motion in Volunteers With Anterior Knee Pain
Recruiting
Background:
- Researchers are interested in how the muscles affect the movement of the knee cap. These muscles may be related to different kinds of knee pain that are not caused by an injury or a disease. Imaging studies such as magnetic resonance imaging (MRI) can be used to look at these muscles. To study these muscles and how they move, researchers will use MRI to look at healthy individuals and individuals with knee cap pain.
Objectives:
- To study how changes to the muscles around the kn... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/03/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Patellofemoral Pain Syndrome
Natural History of Sickle Cell Disease
Recruiting
This study is not a treatment protocol and no experimental treatments are involved. Study participants may be seen as needed for clinical, translational and basic research studies, or as medically indicated. Subjects will receive their general medical care outside the NIH and will be seen at our clinic or at CNHS with varying frequency. Subjects may be seen for multiple visits. Subjects may be asked to return for additional testing as needed. Clinical care for patients with sickle cell disease w... Read More
Gender:
ALL
Ages:
Between 2 years and 90 years
Trial Updated:
06/27/2025
Locations: Suburban Hospital, Bethesda, Maryland +1 locations
Conditions: Pain Crisis
Using Technology to Track Pain and Pain-related Outcomes
Recruiting
Persistent pain is a public health epidemic. The current protocol seeks to develop technology to aid patients' tracking of patients' pain, medications and pain-related variables. The investigators seek to talk with patients in co-investigator's clinic to solicit feedback, as well as pilot test the technology with pain patients.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
06/25/2025
Locations: Behavioral Medicine Research Lab, Baltimore, Maryland
Conditions: Pain, Chronic
MRI Study of Musculoskeletal Function
Recruiting
This study will use magnetic resonance imaging (MRI) and ultrasound images to study how muscles, tendons, and bones work together to cause motion. The procedure is one of several tools being developed to characterize normal and impaired musculoskeletal function, with the goal of developing improved methods of diagnosis and treatment of movement disorders.
Healthy normal volunteers must be age 5 to unlimited, with or without joint impairment, may be eligible for this study. Volunteers with joint... Read More
Gender:
ALL
Ages:
Between 5 years and 95 years
Trial Updated:
06/24/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Abnormalities, Imaging, Patellofemoral Pain Syndrome
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
06/24/2025
Locations: Luana Colloca, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Neural Mechanisms of Immersive Virtual Reality in Chronic Pain (VR TMD EEG)
Recruiting
This project examines, in chronic pain, the mechanisms of immersive virtual reality compared to the mechanisms of placebo hypoalgesia. The potential of developing new non-pharmacological premises for low-risk interventions for pain management is high.
Gender:
ALL
Ages:
Between 18 years and 88 years
Trial Updated:
06/24/2025
Locations: Luana Colloca, Baltimore, Maryland +1 locations
Conditions: Pain, Virtual Reality, Placebo, Temporomandibular Disorder
Neural Correlates of Hypoalgesia Driven by Observation
Recruiting
Placebo effects held an ambivalent place in health care for at least two centuries. On the one hand, placebos are traditionally used as controls in clinical trials to correct for biases and the placebo response is viewed as an effect to be factored out in order to isolate and accurately measure the effects of the treatment. On the other hand, there is scientific evidence that placebo effects represent fascinating psychoneurobiological events involving the contribution of distinct central nervous... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
06/24/2025
Locations: University of Maryland, Baltimore, Maryland
Conditions: Pain, Virtual Reality, Placebo