The city of Boston, Massachusetts, currently has 17 active clinical trials seeking participants for Healthy research studies.
A Study to Evaluate the PK and PD of IM or SQ Injections of Levonorgestrel Butanoate (LB) for Female Contraception
Recruiting
This is a Phase I multicenter, open-label, dose-ranging, three-dose PK and PD study of injectable LB administered as an IM or SQ injection at 40 mg, and subsequently at 50mg SQ and then 60 mg SQ depending on the preliminary pharmacokinetic and pharmacodynamic results obtained with 40 mg dosing.
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
08/11/2023
Locations: Boston Medical Center Corporation, Boston, Massachusetts
Conditions: Healthy Women, Female Contraception
Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance
Recruiting
This study utilizes infusions of kisspeptin in healthy women to isolate the impact of kisspeptin on beta-cell responsivity assessed by the mixed meal tolerance test.
Gender:
Female
Ages:
Between 18 years and 40 years
Trial Updated:
07/17/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Insulin, Glucose, Healthy Volunteers, Women, Pregnancy
A Mobile Tai Chi Platform for Fall Prevention in Older Adults - Phase II
Recruiting
This is a single-arm longitudinal feasibility study for older adults that involves a 12-week home-based Tai Chi program and includes four remote and/or in-person data collection visits. The investigators will collect additional clinical data in a subset of participants who agree to undergo additional assessments in the Motion Analysis Laboratory at the Spaulding Rehabilitation Hospital in Boston, MA during two in-person data collection sessions. The investigators will assess feasibility and acce... Read More
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
07/13/2023
Locations: Spaulding Rehabilitation Hospital, Boston, Massachusetts
Conditions: Healthy Aging
Imaging Brain Fluids During Breathing
Recruiting
This study will perform magnetic resonance imaging (MRI) measurements of hemodynamics and cerebrospinal fluid flow across breathing tasks and during breath-locked neuromodulation.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/14/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Healthy
The Accuracy Of A Novel Platelet Activity Assay In Humans On Antiplatelet Agents: Pharmacodynamics And Comparison With Light Transmission Aggregometry
Recruiting
The purpose of this study is to test a novel diagnostic immunoassay of platelet function and compare it to the current gold standard platelet function assay by testing the response to aspirin and clopidogrel in a group of healthy volunteers and severely obese individuals and comparing the accuracy of the two tests. The secondary goals will be to evaluate the pharmacodynamic parameters of the antiplatelet agents across the two testing modalities and refine the cutoffs used for the novel assay.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/31/2022
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Platelet Activation Testing Before/After Anti-platelet Therapy, Healthy