The state of Massachusetts currently has 6 active clinical trials seeking participants for Narcolepsy research studies. These trials are conducted in various cities, including Boston, Worcester, Springfield and Burlington.
Improving Social Relationships for Adolescents With Central Disorders of Hypersomnolence
Recruiting
The goal of this study is to test a web-based psychoeducational resource for adolescents with central disorders of hypersomnolence and their families. The investigators hope to assess the website's usability, acceptability, and feasibility, as well as its potential effect on social relationship health. Participants will be asked to review the content of the psychoeducational websites. The participants will then provide feedback on the website, as well as the adolescent's social relationships an... Read More
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
04/12/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
04/10/2024
Locations: Neurocare, Inc, Newton, Massachusetts
Conditions: Narcolepsy
Child and Adolescent Registry for Participants With Narcolepsy
Recruiting
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed. The study has 16 active clinical sites and a virtual site that widens participation to anywhere in the United States. For more information about the study or to access the Online Patient Enrollment System, visit the CATNAP website: https://catnap.healthie.net/welcome or email catnap@pulseinfoframe.com.... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
03/28/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 and type 2 narcolepsy from previous parent studies, TAK-861-2001 (NCT05687903) and TAK-861-2002 (NCT05687916).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
02/15/2024
Locations: Neurocare Inc, Newton, Massachusetts
Conditions: Narcolepsy Type 1, Narcolepsy Type 2
A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy
Recruiting
This study is a multi-center, double-blind, placebo-controlled, randomized Phase 3 trial to assess the safety and efficacy of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness (EDS).
Gender:
All
Ages:
Between 15 years and 75 years
Trial Updated:
03/03/2023
Locations: Clinical Research Site, Newton, Massachusetts +1 locations
Conditions: Narcolepsy, Cataplexy, Excessive Daytime Sleepiness
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
Recruiting
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life. The goal is to develop a clinical survey that can improve the care of pediatric narcolepsy.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
05/26/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy, Obstructive Sleep Apnea