There are currently 126 clinical trials in Springfield, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Baystate Medical Center, Mercy Medical Center, GSK Investigational Site and Baystate Med Ctr of Springfield. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Improving Participation in Pulmonary Rehabilitation Through Peer Support and Storytelling
NCT05399056
Recruiting
Chronic Obstructive Pulmonary Disease (COPD) affects approximately 16 million Americans and is characterized by recurrent exacerbations that lead to 1.5 million Emergency Department visits and 700,000 hospitalizations annually. Pulmonary rehabilitation (PR) is a structured program of exercise and self-management support that has been proven to relieve shortness of breath and increase quality of life when initiated after an exacerbation, but unfortunately, few eligible patients participate. This... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
03/21/2023
Locations: Baystate Health, Springfield, Massachusetts
Conditions: Chronic Obstructive Pulmonary Disease
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Stepped Care vs Center-based Cardiopulmonary Rehabilitation for Older Frail Adults Living in Rural MA
NCT05562037
Recruiting
This feasibility trial will focus on older adults 60+ who are candidates for cardiac or pulmonary rehabilitation and who are vulnerable, mildly or moderately frail. We will randomize older frail adults living in rural regions of the county to Treatment as usual (TAU) or Stepped care (SC). TAU refers to center-based rehabilitation (CBR). Patients randomized to SC will be enrolled in traditional CBR and based on prespecified non-response criteria, will step up to three services: 1) Transportation-... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
03/01/2023
Locations: Baystate Health, Springfield, Massachusetts
Conditions: Angina, Stable, Congestive Heart Failure, Chronic Obstructive Pulmonary Disease
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TruGraf® Long-term Clinical Outcomes Study
NCT04491552
Recruiting
This is a prospective, multi-center, observational study. Subjects will have OmniGraf™ (TruGraf® and TRAC™) testing at study enrollment and thereafter every 3 months. In addition subjects will have OmniGraf™ (TruGraf® and TRAC™) testing at any time there is a clinical suspicion of acute rejection. Data collection for the primary objective extends over a 2-year period.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/10/2022
Locations: Renal and Transplant Associates of New England, Springfield, Massachusetts
Conditions: Kidney Transplant Rejection
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Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
NCT04625647
Recruiting
This phase II Lung-MAP treatment trial studies the effect of AMG 510 in treating non-squamous non-small cell lung cancer that is stage IV or has come back (recurrent) and has a specific mutation in the KRAS gene, known as KRAS G12C. Mutations in this gene may cause the cancer to grow. AMG 510, a targeted treatment against the KRAS G12C mutation, may help stop the growth of tumor cells.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/09/2022
Locations: Baystate Medical Center, Springfield, Massachusetts
Conditions: Lung Adenocarcinoma, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Squamous Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
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Machine Learning Sepsis Alert Notification Using Clinical Data
NCT04005001
Recruiting
Machine learning is a powerful method to create clinical decision support (CDS) tools, when training labels reflect the desired alert behavior. In our Phase I work for this project, we developed HindSight, an encoding software that was designed to examine discharged patients' electronic health records (EHRs), identify clinicians' sepsis treatment decisions and patient outcomes, and pass those labeled outcomes and treatment decisions to an online algorithm for retraining of our machine-learning-b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/27/2022
Locations: Baystate Health, Springfield, Massachusetts
Conditions: Sepsis, Severe Sepsis, Septic Shock
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BMI-Associated Labor Induction: A Prospective Trial
NCT04035382
Recruiting
The primary objective of this study is to determine if planned induction of labor at 39 weeks for nulliparous with pre-pregnancy BMI ≥ 35 kg/m2 reduces the incidence of cesarean section compared to expectant management
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/11/2022
Locations: Baystate Medical Center, Springfield, Massachusetts
Conditions: Labor Induction
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