The state of Michigan currently has 47 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Ann Arbor, Detroit, Grand Rapids and Kalamazoo.
EPPIC: Easing Pelvic Pain Interventions Clinical Research Program
Recruiting
The EPPIC (Easing Pelvic Pain Interventions Clinical Research Program) study evaluates an ultra-brief, 4 session cognitive behavioral pain treatment transdiagnostic in design for urologic chronic pain syndrome (UCPPS) with clinical and practical advantages over existing behavioral therapies whose length and focus limits their adoption by clinicians and coverage for mechanistically similar comorbidities. A theoretically informed, practical, empirically grounded approach will systematically unpack... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/11/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Urologic Chronic Pelvic Pain Syndrome (UCPPS), Interstitial Cystitis, Bladder Pain Syndrome, Chronic Prostatitis, Chronic Pain, Chronic Pelvic Pain Syndrome, Chronic Overlapping Pain Disorders
Surgical Treatments for Postamputation Pain
Recruiting
This is a double-blind randomised controlled trial (RCT) which compares the effectiveness of three surgical techniques for alleviating residual limb pain (RLP), neuroma pain and phantom limb pain (PLP). The three surgical treatments are Targeted Muscles Reinnervation (TMR), Regenerative Peripheral Nerve Interface (RPNI), and an active control (neuroma excision and muscle burying). Patients will be follow-up for 4 years.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: University of Michigan Health System, Ann Arbor, Michigan
Conditions: Amputation Neuroma, Phantom Limb Pain, Pain, Neuropathic, Pain, Nerve, Residual Limb Pain
Tailored Pain Guide (TPG) Study
Recruiting
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for chronic low back pain. This research will try to understand how much an electronic, self-management website like PainGuide can help participants. The study hypothesizes that tailored digital interventions (plus using PainGuide) will demonstrate greater improvement in pain interference.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Chronic Lower Back Pain
Burst Spinal Cord Stimulation (Burst-SCS) Study
Recruiting
Recently a new form of spinal cord stimulation therapy called burst spinal cord stimulation (Burst-SCS) is available to treat chronic pain. The goal of this study is to learn more about how Burst-SCS works to reduce chronic pain. The study will examine chronic pain patients who have been deemed candidates for Burst-SCS therapy, and who have already been selected to receive a temporary externalized trial of Burst-SCS from their own doctors as part of their standard clinical care for chronic pain... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Pain, Chronic, Failed Back Surgery Syndrome
Healing Opioid Misuse and Pain Through Engagement (HOPE) Trial
Recruiting
This study is a multisite randomized clinical trial of a treatment designed to reduce pain interference while simultaneously addressing relapse prevention among individuals who have co-occurring chronic pain and Opioid Use Disorder (OUD). This study will recruit approximately 160 individuals who are currently being treated in clinics specializing in the physician management of OUD. To increase generalizability of study findings and increase internal validity of the physician management component... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2023
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Opioid Use Disorder, Chronic Pain
Applying Pain Adaptability to Manual Therapy Practice
Recruiting
Mechanism research has identified pain adaptive and non-adaptive phenotypes by documenting the response to an ice immersion bath. Pain adaptive individuals exhibited a rapid response to cold and a rapid resolution of symptoms with continued exposure. Non-pain adaptive individuals had the opposite. Pain-adaptive individuals have the endogenous (internal) capacity to self-modulate pain therefore may pursue active self management techniques, whereas non-pain adaptive phenotypes may be more prone to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/28/2022
Locations: The Therapy Institute, Haslett, Michigan
Conditions: Musculoskeletal Manipulations, Low Back Pain
Efficacy of Local Anesthetic Through Continuous Infusion
Recruiting
Efficacy of using continuous infusion of local anesthetic for post operative pain control following laparotomy.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2022
Locations: Ascension Genesys Hospital, Grand Blanc, Michigan
Conditions: Pain Control
Are Adductor Canal Blocks With Bupivacaine and Added Magnesium Better at Managing Post-operative Pain Than Bupivacaine and Added Buprenorphine in Patients Undergoing Same-day Discharge Total Knee Arthroplasty?
Recruiting
The purpose of this study is to compare the use of magnesium and bupivacaine to buprenorphine and bupivacaine in post-operative adductor canal blocks (ACB); the study will determine if one combination can result in decreased opioid consumption and improved pain management for patients after same-day discharge total knee arthroplasty (TKA) . The investigators will assess whether the addition of magnesium to bupivacaine will decrease visual analog scale (VAS) pain scores, decrease post-operative... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/22/2021
Locations: St. Joseph Mercy Oakland Hospital, Pontiac, Michigan
Conditions: Post-operative Pain, Acute, Opioid Use
Serratus Anterior Plane Block With and Without Adjuvants in Video-assisted Thoracoscopy
Recruiting
The purpose of this study is to determine whether the addition of the serratus anterior plane block (SAPB) alone (30 mL of 0.25% bupivacaine) or plus Magnesium (150 mg of magnesium sulfate) or plus Magnesium + Buprenorphine (300 mcg) as adjuvants can improve post-operative pain in patients undergoing video-assisted thoracoscopic surgery.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/12/2021
Locations: St. Joseph Mercy Oakland Hospital, Pontiac, Michigan
Conditions: Post Operative Pain, Acute
Are Superficial Parasternal Intercostal Plane (SPIP) Blocks With Bupivacaine and With or Without Adjuvants Helpful for Post-operative Pain After Coronary Artery Bypass Grafting?
Recruiting
The purpose of this study is to determine whether the addition of the superficial parasternal intercostal plane (SPIP) block alone (30cc of 0.25% bupivacaine) or plus Magnesium (200mg of magnesium sulfate) or plus Magnesium + Buprenorphine (300mcg) as adjuvants can improve post-operative pain in patients undergoing cardiothoracic surgery, specifically, coronary artery bypass grafting (CABG)
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
08/11/2021
Locations: St. Joseph Mercy Oakland Hospital, Pontiac, Michigan
Conditions: Post-operative Pain Management
Using Cannabidiol to Treat Diabetic Peripheral Neuropathy of the Feet
Recruiting
The purpose of the study is to evaluate whether PG-DN-20WS is a better pain reliever in patients with diabetic neuropathic pain of the feet than a placebo.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/01/2021
Locations: Pure Green Pharmaceuticals, Bloomfield Township, Michigan
Conditions: Diabetic Peripheral Neuropathic Pain