The city of Detroit, Michigan, currently has 6 active clinical trials seeking participants for Pain research studies.
CARE-CP (Testing a Cardiovascular Ambulatory Rapid Evaluation for Patients With Chest Pain)
Recruiting
The goal of this study is to determine if rapid outpatient evaluation vs hospitalization management is the best strategy (based on patient-centered measures and safe, equitable, and efficient resource use) for evaluating patients with acute chest pain who are at moderate risk for acute coronary syndrome (ACS). Patients will be randomized in the Emergency Department to either an outpatient evaluation (CARE-CP) or hospitalization evaluation for their symptoms.
Gender:
All
Ages:
21 years and above
Trial Updated:
04/23/2024
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: Chest Pain
Intermittent Bolus vs Continuous Infusion Via ESP Catheters RCT
Recruiting
The purpose of this prospective randomized controlled trial is to compare the effectiveness of two different delivery methods for postoperative pain management following cardiac surgery requiring median sternotomy: intermittent programmed LA bolus versus continuous LA infusion through ESP catheters. Effectiveness of analgesia will be assessed based on the subjects' NRS pain scores and opioid consumption. The primary outcome measure will be the patients' opioid consumption over the course of the... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
04/03/2024
Locations: Henry Ford Hospital, Detroit, Michigan
Conditions: Post Operative Pain
Cannabidiol, Morphine, Pain
Recruiting
The purpose of the proposed study is to investigate the interaction of cannabidiol (CBD) and morphine effects on pain sensitivity. Cannabidiol is a cannabinoid (similar to cannabis, or marijuana) present in marijuana that alters some of the effects of marijuana.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/27/2024
Locations: Tolan Park Medical Building, Detroit, Michigan
Conditions: CBD, Chronic Pain
Comparing Analgesic Regimen Effectiveness and Safety for Surgery (CARES) Trial
Recruiting
This trial is being completed to compare two commonly used options to treat pain after surgery. Participants that undergo gallbladder removal, hernia repair, and breast lump removal will be eligible to enroll. Eligible participants will be randomized to 1 of 2 groups of medications (Non-Steroidal Anti-Inflammatory Drugs (NSAIDS) plus acetaminophen or low dose opioids plus acetaminophen). It is anticipated that the NSAID group will have superior clinical outcomes and fewer side effects when comp... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Henry Ford Health System, Detroit, Michigan
Conditions: Surgery, Pain, Postoperative
Opioid-Free Pain Protocol After Shoulder Arthroplasty
Recruiting
This randomized, single blinded, clinical trial aims to investigate the efficacy of a multimodal pain control regimen for shoulder arthroplasty. Patients who receive a multimodal pain control regimen alone (study group) will be compared to patients who receive a multimodal pain control regimen plus a standard prescription of an opioid containing medication (comparison group). The primary outcome is average daily Numerical Rating Scale (NRS) pain score in the first 10 days after surgery. We hypot... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2024
Locations: Henry Ford Health, Detroit, Michigan
Conditions: Shoulder Arthropathy, Shoulder Pain
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Recruiting
Chronic musculoskeletal pain (CP) is a major public health concern. Psychosocial treatments have been shown to be efficacious when compared to largely inert control conditions, but they are characterized by modest effects on primary outcomes. One strategy to boost efficacy is to increase our understanding of treatment mediators. Studies of mediators that directly compare different treatments with each other are needed to determine which mediators are treatment-specific, which are shared across t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/16/2023
Locations: Wayne State University, Detroit, Michigan
Conditions: Chronic Pain, Neck Pain, Back Pain