The state of Minnesota currently has 38 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
PK and Safety in Participants Taking Obicetrapib With Moderate Hepatic Impairment Relative to Normal Hepatic Function
NCT06048302
Recruiting
To investigate the safety and pharmacokinetics in patients with moderate hepatic impairment compared to healthy participants after a single oral dose of obicetrapib (10 mg).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
01/20/2024
Locations: Nucleus Network, Saint Paul, Minnesota
Conditions: Hepatic Impairment, Healthy
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Intracardiac Flow Assessment in Cardiac Amyloidosis
NCT05379101
Recruiting
The primary objective of this study is to define the intracardiac flow imaging biomarkers in cardiac amyloidosis.
Gender:
All
Ages:
40 years and above
Trial Updated:
01/02/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Amyloidosis Cardiac, Healthy Adults
Register for Updates
The Effect of Synaquell™ in Contact Sport Athletes
NCT06104670
Recruiting
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
12/16/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
A Study of Adipose Tissue in Adaptive Responses to Exercise
NCT06053125
Recruiting
The purpose of this research is to determine how exercise affects fat (adipose) tissue and how changes to adipose tissue that occur during and after exercise might improve health in aging and obesity.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
12/01/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Obesity
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Studying the Hedonic and Homeostatic Regulation of Food Intake Using Functional MRI
NCT05525845
Recruiting
The purpose of this study is to investigate how gut hormones and brain areas respond differently to gastric distention, tasteless calories, or palatable food and how this alters appetite.
Gender:
All
Ages:
Between 21 years and 50 years
Trial Updated:
11/27/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics
NCT04466566
Recruiting
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal. The purpose of this research study to find out how genetic variations in GLP1R alter insulin secretion, in the fasting state and when blood sugars levels are elevated.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
11/22/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Beetroot Juice and Sleep
NCT05864521
Recruiting
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/02/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Longitudinal Study to Determine the Effectiveness of the Mobility Checkup for Older Adults
NCT05745402
Recruiting
The investigators are developing a new, preventative physical therapy model of care for older adults called Mobility Checkup (MC). Proposed as an annual visit, the MC includes measurement of physical performance and education regarding the importance of maintaining mobility for overall health. The purpose of this study is to determine the feasibility of and begin data collection for, a longitudinal study of the effectiveness of the Mobility Checkup with a small cohort. This activity will evaluat... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
09/25/2023
Locations: College of St. Scholastica-Health Science Center, Duluth, Minnesota
Conditions: Healthy Aging
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A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation
NCT04880226
Recruiting
The result of these studies will be used to improve patient care through assessment of new technology to determine whether it is beneficial (i.e. improving data acquisition speed or image quality) during iMRI procedures.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/21/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Effects of Energy Drinks on Sleep and Cardiovascular Health
NCT05503732
Recruiting
The purpose of this study is to learn about the change in quality of sleep, structural organization of sleep, and cardiovascular responses after consuming an energy drink compared to a placebo drink with no caffeine or stimulants.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Caffeine
Register for Updates
Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/25/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
Register for Updates
State Dependence of Prefrontal Transcranial Magnetic Stimulation
NCT05962385
Recruiting
The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while receiving transcranial magnetic stimulation. The study will measure change in brain function with EEG.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/24/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy
Register for Updates