The state of Minnesota currently has 37 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
A Study to Evaluate the Effect of Genetic Variation on Beta-cell Function During Fasting and Hyperglycemia in Nondiabetics
NCT04466566
Recruiting
The GLP-1 receptor (GLP1R) gene is found on the beta cells of the pancreas. Its role is in the control of blood sugar level by enhancing insulin secretion from the pancreas after eating a meal. The purpose of this research study to find out how genetic variations in GLP1R alter insulin secretion, in the fasting state and when blood sugars levels are elevated.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
11/22/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Beetroot Juice and Sleep
NCT05864521
Recruiting
The purpose of this study is to investigate the effects of acute inorganic nitrate supplementation (with beetroot) on the regulation of sleep and neurovascular physiology.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
10/02/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Longitudinal Study to Determine the Effectiveness of the Mobility Checkup for Older Adults
NCT05745402
Recruiting
The investigators are developing a new, preventative physical therapy model of care for older adults called Mobility Checkup (MC). Proposed as an annual visit, the MC includes measurement of physical performance and education regarding the importance of maintaining mobility for overall health. The purpose of this study is to determine the feasibility of and begin data collection for, a longitudinal study of the effectiveness of the Mobility Checkup with a small cohort. This activity will evaluat... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
09/25/2023
Locations: College of St. Scholastica-Health Science Center, Duluth, Minnesota
Conditions: Healthy Aging
Register for Updates
A Study to Evaluate Non-significant Risk Operation Magnetic Resonance Imaging for MRI Guided Ablation
NCT04880226
Recruiting
The result of these studies will be used to improve patient care through assessment of new technology to determine whether it is beneficial (i.e. improving data acquisition speed or image quality) during iMRI procedures.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/21/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Register for Updates
Effects of Energy Drinks on Sleep and Cardiovascular Health
NCT05503732
Recruiting
The purpose of this study is to learn about the change in quality of sleep, structural organization of sleep, and cardiovascular responses after consuming an energy drink compared to a placebo drink with no caffeine or stimulants.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Caffeine
Register for Updates
Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/25/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
Register for Updates
State Dependence of Prefrontal Transcranial Magnetic Stimulation
NCT05962385
Recruiting
The study will examine whether the benefits of brain stimulation on mental functioning can be enhanced if an individual is actively engaging the target brain networks while receiving brain stimulation. The study includes two separate sessions and people will complete either a cognitive task or a perceptual task while receiving transcranial magnetic stimulation. The study will measure change in brain function with EEG.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
08/24/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy
Register for Updates
TMS-EEG for Cortical Excitability
NCT05472363
Recruiting
This research study is being done to look at the safety and diagnostic benefit of conducting an TMS(transcranial magnetic stimulation)-EEG measured before and after a brief experimental stimulation session using investigational devices repetitive TMS or transcranial direct current stimulation (tDCS).
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Acquired Brain Injury, Stroke, Traumatic Brain Injury, Healthy
Register for Updates
A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
NCT04984473
Recruiting
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/24/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy, Heart Failure
Register for Updates
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
NCT00785525
Recruiting
The purpose of the study is to: Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in normal dono... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
07/21/2023
Locations: Be The Match, Minneapolis, Minnesota
Conditions: Healthy
Register for Updates
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
NCT05699200
Recruiting
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/05/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Spontaneous Coronary Artery Dissection, Healthy
Register for Updates
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
NCT05264727
Recruiting
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
05/30/2023
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Type 2 Diabetes, Obesity
Register for Updates