The state of Minnesota currently has 30 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
Investigating Brain Function in People With and Without Visual Snow Syndrome Using Adaptation to Visual Stimuli
Recruiting
The goal of this study is to learn more about the brain pathways and activity involved in creating Visual Snow Syndrome (VSS). The main questions it aims to answer are: * Does VSS arise from spontaneous activity in brain pathways? * Where in the brain does the activity contributing to VSS arise? * How does brain activity contribute to VSS? Participants will: 1. Undergo assessments and questionnaires to understand visual and mental symptoms, cognitive, and sensory function. 2. Make visual judg... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
06/11/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Visual Snow Syndrome, Migraine, Healthy
A Study to Analyze the Role of Sympathetic Nervous System in Spontaneous Coronary Artery Dissection
Recruiting
The purpose of this research is to compare sympathetic function (flight or fight system) and arterial health including structure and mechanics of participants with history of spontaneous coronary artery dissection (SCAD) to age and sex matched control participants.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/10/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Spontaneous Coronary Artery Dissection, Healthy
A Comparison of Neuromuscular Recruitment in Trained and Untrained Adults
Recruiting
The objective of the study is to use neurological techniques to obtain quantitative measurements of nervous system control of skeletal muscle activity in adults aged 60-85 who are either long-term resistance exercisers or who are untrained.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
06/04/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy, Insulin Resistance
Integrated Cancer Repository for Cancer Research
Recruiting
The iCaRe2 is a multi-institutional resource created and maintained by the Fred \& Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant percentage of small and rural hospitals and cancer centers. The iCaRe2 advances comprehensive studies of risk factors of cancer... Read More
Gender:
ALL
Ages:
Between 19 years and 110 years
Trial Updated:
06/04/2025
Locations: Riverwood Healthcare Center, Aitkin, Minnesota +4 locations
Conditions: Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer, Thymus Cancer, Colon Cancer, Rectal Cancer, Anal Cancer, Bile Duct Cancer, Duodenal Cancer, Gallbladder Cancer, Gastric Cancer, Liver Cancer, Small Intestine Cancer, Peritoneal Surface Malignancies, Familial Adenomatous Polyposis, Lynch Syndrome, Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Testicular Cancer, Ureter Cancer, Urethral Cancer, Hypopharyngeal Cancer, Laryngeal Cancer, Lip Cancer, Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Paranasal Sinus Cancer, Nasal Cavity Cancer, Salivary Gland Cancer, Skin Cancer, Mesothelioma, Breast Cancer, Leukemia, Melanoma, Sarcoma, Unknown Primary Tumor, Multiple Myeloma, Ovarian Cancer, Endometrial Cancer, Vaginal Cancer, Neuroendocrine Tumors, Plasma Cell Dyscrasia, Healthy Control, Gastrointestinal Stromal Tumors, Central Nervous System Tumor, Central Nervous System Cancer
Glucagon Suppression by Hyperglycemia in the Presence and Absence of Amino Acid Infusion
Recruiting
This study is being done to better understand how amino acids alter the release of glucagon and insulin compared to glucose alone in health and disease.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
05/30/2025
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Healthy, Type 2 Diabetes, Obesity
The Effect of Synaquell™ in Contact Sport Athletes
Recruiting
This research is being done to investigate the dietary supplement, Synaquell (TM), for effects on brain function in youth contact sport athletes.
Gender:
ALL
Ages:
Between 13 years and 19 years
Trial Updated:
05/07/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Recruiting
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/16/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
Parent-Child EF Intervention
Recruiting
Koronis Biomedical Technologies Corporation (KBT) is developing a cognitive intervention to promote healthy development of Executive Function (EF) skills in young children by leveraging a smartphone-based training regime designed for parents.
Gender:
ALL
Ages:
Between 2 years and 5 years
Trial Updated:
04/10/2025
Locations: University of Minnesota, Institute of Child Development, Minneapolis, Minnesota
Conditions: Cognitive Intervention to Promote Healthy Development of Executive Function (EF) Skills in Young Children
Filgrastim-Mobilized Stem Cells for Transplantation Using Unrelated Donors
Recruiting
The purpose of the study is to: * Establish and evaluate a system for collection of filgrastim-mobilized peripheral blood stem cells from National Marrow Donor Program donors (NMDP) donors * Assess the safety among NMDP donors of filgrastim administration and PBSC leukapheresis * Assess the safety and efficacy of filgrastim-mobilized PBSC in unrelated donor hematopoietic stem cell transplant recipients * Determine the acceptability of stem cell donation by filgrastim stimulated apheresis in nor... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/09/2025
Locations: Be The Match, Minneapolis, Minnesota
Conditions: Healthy
Registry for Mayo Clinic Adult Congenital Heart Disease Control Population
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
03/31/2025
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy
A Study of Pulmonary Hypertension Peripheral Limitations
Recruiting
The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial Hypertension (PAH).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Arterial Hypertension, Healthy
Food at Home Study
Recruiting
The study objective is to develop an accessible home food environment assessment toolkit that includes valid and reliable paper and electronic tools targeting foods known to impact diet-related health that can be user-administered across literacy levels in English and Spanish.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
03/21/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Diet, Healthy