The state of Minnesota currently has 37 active clinical trials seeking participants for Healthy research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
ChronoMet: Metabolic and Inflammatory Effects of Eating Timing and Quantity
Recruiting
This is an observational study to address the important knowledge gap of the metabolic and inflammatory impact of acute overeating and whether timing of acute overeating may modify these effects. The hypothesis is that acute overconsumption of calories will promote inflammation and metabolic dysfunction, with the most detrimental effects observed with evening caloric overconsumption. The expectation is that this study to provide critical insights into the biological consequences of overeating, w... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/16/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Healthy Volunteers
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
Recruiting
The purpose of this study is to evaluate pulmonary capillary wedge pressure (PCWP) and other hemodynamic measurements at rest and during exercise in healthy volunteers across the age spectrum.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/16/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
Effects of Vitamin B3 Derivative Nicotinamide Riboside (NR) in Bone, Skeletal Muscle and Metabolic Functions in Aging
Recruiting
Researchers are trying to determine if the vitamin B3 derivative Nicotinamide Riboside (NR) has any effects in bone, skeletal muscle, and metabolic functions and structure in aging.
Gender:
Female
Ages:
Between 65 years and 80 years
Trial Updated:
04/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy Elderly Volunteers
A Study to Learn How Various Tablets of the Study Medicine Vepdegestrant Are Taken up Into the Blood of Healthy Adults
Recruiting
The purpose of the study is to look at how various tablets of a study medicine called vepdegestrant are processed in the body. This will be studied in healthy adult participants after food. This study looks at how the medicine is changed and removed from the body after a participant takes it. This study is seeking for participant who: are healthy males, and healthy females who do not have the possibility to have children. are 18 years of age or older. weigh more than 45 Kilograms (99 pounds).... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: Prism Research LLC dba Nucleus Network, Saint Paul, Minnesota
Conditions: Healthy
Food at Home Study
Recruiting
The study objective is to develop an accessible home food environment assessment toolkit that includes valid and reliable paper and electronic tools targeting foods known to impact diet-related health that can be user-administered across literacy levels in English and Spanish.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/12/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Obesity, Diet, Healthy
A Study of TopSpin360 Training Device
Recruiting
This research is being done to investigate the novel neck strengthening device, TopSpin360 and its effectiveness on measures of neck strength and cognitive function
Gender:
All
Ages:
Between 18 years and 21 years
Trial Updated:
04/06/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Recruiting
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
04/06/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
A Study to Learn About the Study Medicine (Called Lorlatinib) in People With Liver Dysfunction
Recruiting
The purpose of this clinical trial is to learn about the safety and effects of the study medicine (called Lorlatinib) in health participants. This study is seeking participants who: Must be male or female of 18 to 75 years of age, inclusive at the time of the study. Are willing and able to comply with all scheduled visits, treatment plan, and other study procedures. Have a BMI (body mass index) of 17.5 to 40 kg/m2; and a total body weight >50 kg (110 lb). Are capable of giving signed informed c... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/04/2024
Locations: Prism Research LLC dba Nucleus Network, Saint Paul, Minnesota
Conditions: Moderate Hepatic Impairment, Severe Hepatic Impairment, Healthy Volunteers
Registry for Mayo Clinic Adult Congenital Heart Disease Control Population
Recruiting
This research study is being done to provide comparative data to the Mayo Clinic Adult Congenital Heart Disease Registry.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/28/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Healthy
A Study of Pulmonary Hypertension Peripheral Limitations
Recruiting
The investigators are doing this research study to compare whole body aerobic training with isolated leg training (with weights) and its impact on effectiveness in symptoms and quality of life in patients with Pulmonary Arterial Hypertension (PAH).
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Pulmonary Arterial Hypertension, Healthy
Saccharomyces Boulardii CNCM I-745 on Intestinal Barrier Function
Recruiting
This study is being done to assess the effects of S. boulardii CNCM I-745 compared to placebo on impaired intestinal permeability, which is the control of material passing from inside the gastrointestinal tract through the cells lining the gut wall into the rest of the body.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
03/11/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Healthy
Integrated Cancer Repository for Cancer Research
Recruiting
The iCaRe2 is a multi-institutional resource created and maintained by the Fred & Pamela Buffett Cancer Center to collect and manage standardized, multi-dimensional, longitudinal data and biospecimens on consented adult cancer patients, high-risk individuals, and normal controls. The distinct characteristic of the iCaRe2 is its geographical coverage, with a significant percentage of small and rural hospitals and cancer centers. The iCaRe2 advances comprehensive studies of risk factors of cancer... Read More
Gender:
All
Ages:
Between 19 years and 110 years
Trial Updated:
02/29/2024
Locations: Riverwood Healthcare Center, Aitkin, Minnesota +5 locations
Conditions: Pancreatic Cancer, Thyroid Cancer, Lung Cancer, Esophageal Cancer, Thymus Cancer, Colon Cancer, Rectal Cancer, Anal Cancer, Bile Duct Cancer, Duodenal Cancer, Gallbladder Cancer, Gastric Cancer, Liver Cancer, Small Intestine Cancer, Peritoneal Surface Malignancies, Familial Adenomatous Polyposis, Lynch Syndrome, Bladder Cancer, Kidney Cancer, Penile Cancer, Prostate Cancer, Testicular Cancer, Ureter Cancer, Urethral Cancer, Hypopharyngeal Cancer, Laryngeal Cancer, Lip Cancer, Oral Cavity Cancer, Nasopharyngeal Cancer, Oropharyngeal Cancer, Paranasal Sinus Cancer, Nasal Cavity Cancer, Salivary Gland Cancer, Skin Cancer, Mesothelioma, Breast Cancer, Leukemia, Melanoma, Sarcoma, Unknown Primary Tumor, Multiple Myeloma, Ovarian Cancer, Endometrial Cancer, Vaginal Cancer, Neuroendocrine Tumors, Plasma Cell Dyscrasia, Healthy Control, Gastrointestinal Stromal Tumors, Central Nervous System Tumor, Central Nervous System Cancer