The state of Minnesota currently has 11 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Minneapolis, Rochester, Saint Paul and Duluth.
Geniculate Artery Embolization for Osteoarthritis
Recruiting
The need for exploration of more definitive and cost effective non-arthroplasty treatments of osteoarthritis (OA) has been demonstrated by the orthopedic and health economic research. Embolotherapy of neovessels associated with OA joints has been shown to be promising in patients with knee OA. There is a need for level one evidence drawn from randomized clinical trials to prove the safety, feasibility and efficacy of knee embolotherapy compared to standard of care. This randomized pilot study... Read More
Gender:
All
Ages:
Between 40 years and 70 years
Trial Updated:
06/20/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Osteo Arthritis Knee, Arthritis, Osteoarthritis, Osteoarthritis, Knee
Actis Total Hip System 2 Year Follow-up
Recruiting
Two-year (2 year) information regarding the performance of the commercially available Actis™ Total Hip System in order to obtain and evaluate the clinical outcomes on a series of cementless primary total hip arthroplasty (THA) and hemi-hip arthroplasty procedures using clinical, radiographic and device and procedure related adverse event assessments.
Gender:
All
Ages:
21 years and above
Trial Updated:
06/18/2024
Locations: Not set, Rochester, Minnesota
Conditions: Osteoarthritis, Traumatic Arthritis, Rheumatoid Arthritis, Congenital Hip Dysplasia, Avascular Necrosis of the Femoral Head, Acute Traumatic Fracture of the Femoral Head or Neck, Certain Cases of Ankylosis, Non-union of Femoral Neck Fractures, Certain High Sub-Capital & Femoral Neck Fractures in Elderly
Persona OsseoTi Keel Compatibility Study (Total Knee Arthroplasty)
Recruiting
The main objective of the study is to evaluate the safety, performance and clinical benefits of the Persona implant and its instrumentation in primary total knee arthroplasty
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Knee Pain Chronic, Osteoarthritis, Knee, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee, Avascular Necrosis
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
Recruiting
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or saline.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Knee Osteoarthritis, Osteo Arthritis Knee
Zimmer Biomet Shoulder Arthroplasty PMCF
Recruiting
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/09/2024
Locations: TRIA Orthopaedic Center Research Institute, Bloomington, Minnesota
Conditions: Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
Rehabilitation Following Reverse Total Shoulder Arthroplasty
Recruiting
Reverse total shoulder arthroplasty (RTSA) has been successful in patients with rotator cuff arthropathy, proximal humerus fractures, failed primary total shoulder arthroplasty or failed hemiarthroplasty, and massive irreparable rotator cuff tear. Patients who undergo an RTSA report pain relief and functional range of motion. It has been more than 20 years since the advent of the RTSA construct but an immediate post-operative rehabilitation with active shoulder range of motion has not been prosp... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
05/01/2024
Locations: TRIA Orthopaedic Center, Bloomington, Minnesota
Conditions: Shoulder Osteoarthritis
Autologous Culture Expanded Adipose Derived MSCs for Treatment of Painful Hip OA
Recruiting
Will injection(s) of autologous culture-expanded AMSCs be safe and efficacious for treatment of painful Hip OA, and if so, which dosing regimen is most effective?
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/21/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Osteoarthritis, Hip
A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain
Recruiting
There is an urgent public health need to reduce reliance on opioids for effective long-term pain management, particularly in knee osteoarthritis (KOA). This effectiveness trial will compare commonly recommended treatments to reduce pain and functional limitations in KOA.These results will lead to improved patient selection for treatment and inform evidence based guidelines by offering well-tested, effective, non-surgical alternatives.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/07/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Knee Osteoarthritis
Mechanisms of a Dynamic Stability Approach
Recruiting
Background. Arthritis is the leading cause of disability in the United States and osteoarthritis (OA) of the hand affects an estimated 25.6 US residents. OA of the thumb carpometacarpal (CMC) joint is the most disabling form of hand OA. Rehabilitation for persons with thumb CMC OA is recommended as the initial treatment and often involves instruction on joint protection and fitting of a splint to reduce joint stress and pain. More recently, evidence has suggested that specialized exercise may im... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Thumb Carpometacarpal Osteoarthritis, Thumb Basal Joint Osteoarthritis
Persona Revision Knee System Outcomes
Recruiting
The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/27/2023
Locations: TRIA Orthopaedic Center Research Institute, Bloomington, Minnesota
Conditions: Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
Recruiting
The Researchers are trying to compare two different types of intraarticular injections (injection in the joint) for treating the symptoms of moderate to advanced basilar thumb arthritis. One injection is ketorolac (an NSAID) and the other is triamcinolone (a corticosteroid).
Gender:
All
Ages:
40 years and above
Trial Updated:
08/07/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Thumb Osteoarthritis