There are currently 928 clinical trials in Minneapolis, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Minnesota, Hennepin County Medical Center, Abbott Northwestern Hospital and University of Minnesota/Masonic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Molecular and Clinical Risk-Directed Therapy for Infants and Young Children With Newly Diagnosed Medulloblastoma
NCT05535166
Recruiting
This is a multi-center, multinational phase 2 trial that aims to explore the use of molecular and clinical risk-directed therapy in treatment of children 0-4.99 years of age with newly diagnosed medulloblastoma.
Gender:
ALL
Ages:
59 months and below
Trial Updated:
04/16/2025
Locations: Children's Hospital and Clinics of Minnesota, Minneapolis, Minnesota
Conditions: Medulloblastoma
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Prophylactic Antibiotics in Cystectomy With Diversion
NCT06190197
Recruiting
Using a randomized 2 arm design, this study is being conducted to test for non-inferiority of no prophylactic antibiotic therapy versus the prophylactic oral antibiotic, nitrofurantoin, through comparison of rates of postoperative urinary tract infections within the 90-day postoperative period in patients with muscle invasive bladder cancer who undergo radical cystectomy with urinary diversion.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Muscle-Invasive Bladder Carcinoma, Radical Cystectomy, Ileal Conduit, Neobladder Diversion
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Geniculate Artery Embolization for Osteoarthritis
NCT04456569
Recruiting
The need for exploration of more definitive and cost effective non-arthroplasty treatments of osteoarthritis (OA) has been demonstrated by the orthopedic and health economic research. Embolotherapy of neovessels associated with OA joints has been shown to be promising in patients with knee OA. There is a need for level one evidence drawn from randomized clinical trials to prove the safety, feasibility and efficacy of knee embolotherapy compared to standard of care. This randomized pilot study... Read More
Gender:
ALL
Ages:
Between 40 years and 70 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Osteo Arthritis Knee, Arthritis, Osteoarthritis, Osteoarthritis, Knee
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Udall Project 1 Aim 4
NCT05568199
Recruiting
By defining the strength and direction of connectivity patterns at rest and during movement across the basal ganglia-thalamocortical (BGTC) network we will characterize the role of individual circuits in motor performance and cognitive function, paving the way for future development of optimization algorithms for DBS that take advantage of this understanding.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
04/15/2025
Locations: University Of Minnesota, Minneapolis, Minnesota
Conditions: Parkinsons Disease, Deep Brain Stimulation
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Effects of Walking in Greenspace and the Built Environment in Adults With Prediabetes: A Randomized Crossover Trial
NCT06365723
Recruiting
Approximately 92 million U.S. adults (\~38% of population) have prediabetes (PreD). Because people with PreD are at high risk CMD, they are a target population for diabetes prevention programs. The focus is people with PreD because of their high risk for developing CMD and large numbers, providing an opportunity to investigate behavioral and environmental approaches as preventive measures in a well-defined population. Urbanization affords challenges and opportunities to public health that includ... Read More
Gender:
ALL
Ages:
Between 25 years and 64 years
Trial Updated:
04/15/2025
Locations: Epidemiological Clinical Research Center, Minneapolis, Minnesota
Conditions: PreDiabetes
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Surgical Site Infections and the Microbiome: Understanding the Pathogenesis of Surgical Site Infections
NCT06300892
Recruiting
This is a prospective, observational study of patients undergoing open GI surgery. At the time of operation, samples will be collected from the incision site and GI tract. The study will follow patients up to 30 days postoperatively, monitoring for signs of SSI. Samples will be taken from all patients who develop SSI. Sequencing will be performed on a subset of samples based on our specific aims. * Aim 1: conduct a case-control study of patients with SSI and age-, sex-, diagnosis-, and wound cl... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Open GI Surgery
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Study to Evaluate the Safety and Tolerability of Ferric Citrate in Children With Hyperphosphatemia Related to Chronic Kidney Disease
NCT04523727
Recruiting
This study will be conducted to assess the safety and tolerability of ferric citrate in pediatric participants with hyperphosphatemia related to chronic kidney disease (CKD).
Gender:
ALL
Ages:
Between 6 years and 16 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Hyperphosphatemia Related to Chronic Kidney Disease
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Aim 3 Particle Swarm Optimization PIGD
NCT05934747
Recruiting
In Parkinson's disease (PD) patients undergoing standard-of-care Deep Brain Stimulation (DBS) therapy, to compare the effect on Parkinson's symptoms of two different neurostimulator settings designed to differ from each other as much as possible with respect to how much they activate two different neuroanatomical structures: the axonal pathway from Globus Pallidus (GP) to Pedunculopontine Nucleus (PPN), and the axonal pathway from PPN to GP.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Parkinson's Disease and Parkinsonism
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Personalized Nutrition Therapy Using Continuous Glucose Monitoring to Improve Outcomes in Type 2 Diabetes Mellitus
NCT06465693
Recruiting
Nutrition guidelines state that multiple eating patterns are effective for type 2 diabetes and that therapy should be individualized. Yet many nutrition plans fail to account for interpersonal variability in blood glucose response to meals. This diminishes the ability of dietary interventions to optimize glycemic control and may lessen patient satisfaction, self--efficacy, and adherence. Continuous glucose monitoring (CGM) can facilitate behavior change in type 2 diabetes and has been associated... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Type 2 Diabetes
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Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)
NCT05417789
Recruiting
This is a multicenter, Phase 3, randomised, double-blind, placebo-controlled study, which aims to evaluate the efficacy and safety of the investigational drug emactuzumab for the treatment of patients with localized or diffuse TGCT where surgical removal of the tumor is not viewed as an option. The study consists of two parts. In Part 1, eligible subjects will be assigned in a 2:1 ratio to receive either emactuzumab or matching placebo in a double-blind fashion, that will be administered in tot... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: TGCT
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Remotely Delivered Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery After Spinal Cord Injury
NCT05870189
Recruiting
So far, therapies have limited success in functional recovery in adults with chronic SCI. By introducing remote cognitive multisensory rehabilitation (CMR), which has shown significant functional improvements due to neurological recovery when delivered in-person, transformative results that (i) provide a potentially effective new therapy within the healthcare system, accessible to more patients, and (ii) demonstrate brain function changes alongside improved function in chronic SCI are anticipate... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Spinal Cord Injuries, Spinal Cord Diseases
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BLOODSAFE Ghana- Iron and Nutritional Counselling Strategy
NCT06101238
Recruiting
A randomized trial will compare 6-months of low-dose (65mg elemental iron daily) among prospective blood donors who are deferred for low haemoglobin but have passed all of the other pre-screening requirements for blood donation to a group of donors who were deferred from donating and receive the current standard of care (nutrition counseling only). An automated full blood count (FBC) will also be done to identify any safety concerns. The randomized trial will evaluate effectiveness with the prim... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Blood Donation
Register for Updates