The state of Missouri currently has 31 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Saint Louis, Kansas City, St. Louis and Springfield.
Interdisciplinary Group Care for the Treatment of Endometriosis-associated Pain
NCT06549985
Recruiting
The goal of this clinical trial is to determine if Peer Empowered Endometriosis Pain Support (PEEPS), an 8-week interdisciplinary, integrative group care program, decreases pain interference in participants with endometriosis-associated chronic pelvic pain between the ages 18 and 48. The main question we aim to answer is: Is PEEPS more effective than Education in decreasing pain interference? Researchers will compare people receiving PEEPS plus usual care to those receiving Education plus usua... Read More
Gender:
FEMALE
Ages:
Between 18 years and 48 years
Trial Updated:
02/20/2025
Locations: WashU Medicine, Saint Louis, Missouri
Conditions: Endometriosis, Pelvic Pain
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Post-Op Pain Control for Prophylactic Intramedullary Nailing.
NCT03823534
Recruiting
Nationally, the opioid crisis has become a major epidemic with increasing mortality rates each year. Orthopedic surgeons routinely prescribe narcotics instead of NSAIDs for post-op pain control because of risk of delayed healing and nonunion due to NSAID use. Orthopedic oncology, however, has a unique subset of patients that undergo prophylactic placement of intramedullary femoral nails. Because no fracture is present, these patients do not rely on inflammatory healing factors, allowing for post... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: Saint Louis University, Saint Louis, Missouri
Conditions: Bone Metastases, Lymphoma, Multiple Myeloma, Opioid Use, Pain
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Multi-modal Imaging of Myofascial Pain
NCT06036524
Recruiting
The goal of this study is to develop new imaging biomarkers for quantitative assessments of myofascial pain.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
08/23/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Myofascial Pain
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EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
NCT05476276
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Healthcare Research Network (Hazelwood), Hazelwood, Missouri
Conditions: Painful Diabetic Neuropathy
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Sleep and Pain Interventions in Women With Fibromyalgia
NCT03744156
Recruiting
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: University of Missouri- Department of Psychiatry, Columbia, Missouri
Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
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Local Anesthesia for Facial Fractures
NCT06429501
Recruiting
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics. Patients with operative facial fractures are randomized to receive either bupivacaine or saline injections prior to the anesthesia emergence.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Pain Management
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Personalized Prediction of Persistent Postsurgical Pain
NCT04864275
Recruiting
P5 is planned as a prospective observational study, collecting evidence-based perioperative data on patient history and demographics, physical function, cognitive measures, psychological, and biological markers associated with increased pain susceptibility, and psychophysical measures of pain processing. The study will use daily ecologic momentary assessment (EMA) of physical and emotional parameters, and collect data on perioperative events. Follow up will occur 3 months and 6 months postoper... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2024
Locations: Washington University in St Louis, Saint Louis, Missouri
Conditions: Pain, Postoperative
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