The state of Missouri currently has 34 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Saint Louis, Kansas City, St. Louis and Springfield.
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
NCT05929066
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: StudyMetrix Research, Saint Peters, Missouri +1 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
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Patient Retrospective Outcomes (PRO)
NCT01550575
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Saint Louis Pain Consultants, Chesterfield, Missouri +1 locations
Conditions: Chronic Pain
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Sleep and Pain Interventions in Women With Fibromyalgia
NCT03744156
Recruiting
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia. This trial will yield important information about the roles of sleep, arousal, and brain structure and function in the development and maintenance of chronic pain in women with fibromyalgia.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: University of Missouri- Department of Psychiatry, Columbia, Missouri
Conditions: Fibromyalgia, Insomnia, Chronic Widespread Pain
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RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
NCT01719055
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2024
Locations: Midwest Pain Center, Chesterfield, Missouri +2 locations
Conditions: Pain
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A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)
NCT06203002
Recruiting
Evaluation of the efficacy of LX9211 compared to placebo in reducing DPNP.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: Lexicon Investigational Site (104), Hazelwood, Missouri +2 locations
Conditions: Diabetic Peripheral Neuropathic Pain
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A Phase 2 Study of IW-3300 for the Treatment of Bladder Pain in Subjects With Interstitial Cystitis/Bladder Pain Syndrome
NCT05740007
Recruiting
The aim of this study is to assess whether IW-3300 is safe and works for the treatment of interstitial cystitis/bladder pain syndrome (IC/BPS). The main question the study aims to answer is whether IW-3300 helps bladder pain and other symptoms (for example, bladder burning, pressure and discomfort). Subjects will be assigned to receive either the study drug or placebo by chance.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/30/2024
Locations: Specialty Clinical Research of St. Louis-Objective Health, Saint Louis, Missouri
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
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Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)
NCT06176196
Recruiting
The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/29/2024
Locations: St. Louis Pain Consultants, Chesterfield, Missouri +1 locations
Conditions: Painful Lumbosacral Radiculopathy
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A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: StudyMetrix Research, Saint Peters, Missouri +1 locations
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
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Local Anesthesia for Facial Fractures
NCT06429501
Recruiting
The study is a double-blind randomized, placebo controlled trial examining the impact of perioperative bupivacaine nerve block on PACU recovery metrics. Patients with operative facial fractures are randomized to receive either bupivacaine or saline injections prior to the anesthesia emergence.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/20/2024
Locations: Washington University, Saint Louis, Missouri
Conditions: Pain Management
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Zimmer Biomet Shoulder Arthroplasty PMCF
NCT04984291
Recruiting
The objectives of this study are to confirm the safety, performance, and clinical benefits of Zimmer Biomet Shoulder Arthroplasty Systems and its instrumentation in primary or revision shoulder arthroplasty. These objectives will be assessed using standard scoring systems, radiographic evidence, and adverse event records. Safety of the system will be assessed by monitoring the frequency an incidence of adverse events.
Gender:
All
Ages:
20 years and above
Trial Updated:
05/09/2024
Locations: Washington University, Saint Louis, Missouri +1 locations
Conditions: Shoulder Fractures, Shoulder Arthritis, Shoulder Osteoarthritis, Shoulder Deformity, Shoulder Injuries, Shoulder Pain
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Trial Readiness and Endpoint Assessment in LGMD R1
NCT05618080
Recruiting
This is a 24-month, observational study of 100 participants with Limb Girdle Muscular Dystrophy type R1, also known as CAPN3.
Gender:
All
Ages:
Between 12 years and 50 years
Trial Updated:
05/06/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Calpain-3 Deficiency Limb Girdle Muscular Dystrophy Type 2A, Limb Girdle Muscular Dystrophy, Limb Girdle Muscular Dystrophy Type R1, LGMD2A
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Examining Racial and Socioeconomic Differences in Chronic Low Back Pain
NCT05991440
Recruiting
The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/22/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Chronic Pain
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