There are currently 476 clinical trials in Rochester, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Rochester, University of Rochester Medical Center, James P. Wilmot Cancer Center at University of Rochester Medical Center and Rochester Clinical Research, Inc.. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Otitis Treatment With OtoSight™ - Modification of Antibiotic Treatment Intervention in Children
NCT06285812
Recruiting
A pragmatic, mixed-method trial is to show the ability of OtoSight to change management of the pediatric patient presenting with ear pain in a way that improves patient outcomes and reduces costs.
Gender:
All
Ages:
Between 6 months and 17 years
Trial Updated:
02/28/2024
Locations: Trillim Health, Rochester, New York
Conditions: Otitis Media Acute
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Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
NCT03500328
Recruiting
FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early aggressive therapy with respect to preventing long-term disability. The infectious risks and other complications associated with higher-efficacy treatments highlight the need to quantify their effectiveness in preventing disability. The TRaditional versus Ear... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
02/28/2024
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Multiple Sclerosis, Relapsing-Remitting
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Transitions Clinic Network: Post Incarceration Addiction Treatment, Healthcare, and Social Support
NCT04309565
Recruiting
TCN PATHS will recruit an anticipated 400 participants who are prescribed MOUD who are released from detention facilities. Each individual will be randomized to either 1) standard primary care (SPC) or 2) a Transitions Clinic Network (TCN) program primary care. Participants will be followed for a year and complete surveys at baseline and at month 1, 3, 6, 9, and 12. At each of these points research staff will confirm MOUD status. Urine drug screenings will be completed at baseline, month 1, 6, a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of Rochester, Rochester, New York
Conditions: Opioid Addiction
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Project: Every Child for Younger Patients With Cancer
NCT02402244
Recruiting
This study gathers health information for the Project: Every Child for younger patients with cancer. Gathering health information over time from younger patients with cancer may help doctors find better methods of treatment and on-going care.
Gender:
All
Ages:
25 years and below
Trial Updated:
02/27/2024
Locations: University of Rochester, Rochester, New York
Conditions: Central Nervous System Neoplasm, Childhood Immature Teratoma, Childhood Langerhans Cell Histiocytosis, Childhood Mature Teratoma, Congenital Mesoblastic Nephroma, Lymphoproliferative Disorder, Myeloproliferative Neoplasm, Stromal Neoplasm, Carcinoma In Situ, Malignant Solid Neoplasm, Desmoid Fibromatosis, Ganglioneuroma, Melanocytic Neoplasm, Neuroendocrine Neoplasm
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Pepinemab in Combination With Pembrolizumab in Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
NCT04815720
Recruiting
The purpose of the study is to evaluate the safety and tolerability of pepinemab in combination with pembrolizumab as first-line treatment and determine a recommended Phase 2 dose (RP2D) in patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC).
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
02/26/2024
Locations: University of Rochester, Rochester, New York
Conditions: Recurrent/Metastatic Squamous Cell Carcinoma of the Head and Neck (HNSCC)
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Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort
NCT01574053
Recruiting
Enroll-HD is a longitudinal, observational, multinational study that integrates two former Huntington's disease (HD) registries-REGISTRY in Europe, and COHORT in North America and Australasia-while also expanding to include sites in Latin America. More than 30,000 participants have now enrolled into the study. With annual assessments and no end date, Enroll-HD has built a large and rich database of longitudinal clinical data and biospecimens that form the basis for studies developing tools and b... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: University of Rochester, Rochester, New York
Conditions: Huntington's Disease
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A Study to Determine the Preferred Dose of the Drug, Lisinopril, for Preventing Urinary Toxicity Following Radiotherapy for Prostate Cancer
NCT05530655
Recruiting
This study will establish the preferred dose of lisinopril in men with non-metastatic prostate cancer undergoing radiation treatment. This study will also evaluate the effect of lisinopril on urinary symptoms and the impact of lisinopril on biomarkers and their association with urinary symptoms.
Gender:
Male
Ages:
Between 18 years and 70 years
Trial Updated:
02/23/2024
Locations: Wilmot Cancer Institute, Rochester, New York
Conditions: Prostate Cancer, Radiation Toxicity, Urinary Complication
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Evaluate the Safety of DEXYCU for the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
NCT05191706
Recruiting
A Phase 3/4, Prospective, Randomized, Active Treatment-Controlled, Parallel-Design, Multicenter Study to Evaluate the Safety of DEXYCUfor the Treatment of Inflammation Following Ocular Surgery for Childhood Cataract
Gender:
All
Ages:
3 years and below
Trial Updated:
02/21/2024
Locations: EyePoint Investigational Site, Rochester, New York
Conditions: Cataract
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The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients
NCT05034432
Recruiting
To investigate the effect of VTA ablation at the time of LVAD implant to see if it can reduce the incidence of VTA after surgery
Gender:
All
Ages:
18 years and above
Trial Updated:
02/19/2024
Locations: University of Rochester, Rochester, New York
Conditions: Arrythmia, Cardiomyopathies
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Prospective Case Collection Study for New Mammography Technologies
NCT05199701
Recruiting
To evaluate the safety and efficacy of the proposed investigational device and assess its clinical utility in breast cancer screening and diagnosis to support continuing technology development of the investigational technology.
Gender:
Female
Ages:
Between 35 years and 100 years
Trial Updated:
02/14/2024
Locations: Elizabeth Wendy Breast Care, Rochester, New York
Conditions: Mammography
Register for Updates
Decreasing Polypharmacy in Older Adults With Curable Cancers Trial
NCT05046171
Recruiting
This is a single-site cluster-randomized trial to assess efficacy and implementation outcomes of deprescribing interventions in 72 older adults with polypharmacy (PP) and curable cancers initiating chemotherapy. Oncologists (as the cluster) will enroll 6 patients each and will be randomized to either a pharmacist-led deprescribing intervention or patient education intervention. Initial focus groups with oncologists, nurses, pharmacists, primary care physicians, and patients will provide data for... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
02/13/2024
Locations: University of Rochester, Rochester, New York
Conditions: Cancer
Register for Updates
Observational Study of Pediatric Rheumatic Diseases: The CARRA Registry
NCT02418442
Recruiting
Continuation of the CARRA Registry as described in the protocol will support data collection on patients with pediatric-onset rheumatic diseases. The CARRA Registry will form the basis for future CARRA studies. In particular, this observational registry will be used to answer pressing questions about therapeutics used to treat pediatric rheumatic diseases, including safety questions.
Gender:
All
Ages:
21 years and below
Trial Updated:
02/13/2024
Locations: University of Rochester, Rochester, New York
Conditions: Rheumatic Joint Disease
Register for Updates