There are currently 464 clinical trials in Rochester, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Rochester, University of Rochester Medical Center, James P. Wilmot Cancer Center at University of Rochester Medical Center and Rochester Clinical Research, Inc.. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
NCT05338697
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Strong Memorial Hospital, Rochester, New York
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
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Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
NCT06074315
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: Rochester Clinical Research, LLC, Rochester, New York
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
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Labor Status Monitor for Diagnosing True vs False Labor in Preterm Patients
NCT06157203
Recruiting
This is an observational study of pregnant persons in threatened labor. The study device will record electromyography signals, then the signals will be examined to determine who is in true labor and who is in threatened labor. The two goals are: * To establish the thresholds for the Contraction Synchronization Index (CSI) and the False Labor Index (FSI) to be used by the Labor Status Monitor to diagnose in-Labor or Not-in-Labor for preterm patients with threatened labor * To obtain feedback fro... Read More
Gender:
FEMALE
Ages:
All
Trial Updated:
11/27/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: PreTerm Labor, Threatened Preterm Labor, Preterm Birth
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Congenital Heart Disease GEnetic NEtwork Study (CHD GENES)
NCT01196182
Recruiting
Congenital heart defects (CHD) are the most common major human birth malformation, affecting \~8 per 1,000 live births. CHD are associated with significant morbidity and mortality, and are second only to infectious diseases in contributing to the infant mortality rate. Current understanding of the etiology of pediatric cardiovascular disorders is limited. The Congenital Heart Disease GEnetic NEtwork Study (CHD GENES) is a multi-center, prospective observational cohort study. Participants will b... Read More
Gender:
ALL
Ages:
99 years and below
Trial Updated:
08/29/2023
Locations: University of Rochester, Rochester, New York
Conditions: Congenital Heart Defects
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Prevalence of Humoral Dysfunction in Pts With Frequent Exacerbations of COPD, and the Effect of SCIgR for Prevention
NCT05764993
Recruiting
To examine the prevalence of humoral immunodeficiency in patients with Chronic Obstructive Pulmonary disease (COPD) by evaluating both immunoglobulin levels and vaccine responses. Patients with COPD and humoral dysfunction will be offered treatment with Subcutaneous Immune Globulin Replacement Therapy (SCIgR) in an attempt to decrease future AECOPD.
Gender:
ALL
Ages:
Between 18 years and 82 years
Trial Updated:
06/13/2023
Locations: Rochester Regional Health Ctr for Clinical Research - Alexander Park, Rochester, New York +2 locations
Conditions: COPD Exacerbation Acute
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Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
NCT05486143
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Breast Cancer
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A Prospective Sample Collection Study Using Non-invasive Methods to Investigate Biomarkers in AD Patients
NCT04699695
Recruiting
This is a prospective, multicenter, sample collection study using DermTech's non-invasive skin collection kits to evaluate genomic biomarkers and microbiome information from pediatric and adult subjects with atopic dermatitis(AD). Samples collected will be analyzed to detect gene signatures and microbiome populations associated with AD and sub-populations of AD.
Gender:
ALL
Ages:
1 year and above
Trial Updated:
07/25/2022
Locations: Lisa A. Beck, Rochester, New York
Conditions: Atopic Dermatitis
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Development of Childhood Anti-influenza Immunity
NCT03778203
Recruiting
More information is needed on how children fight off influenza virus, as they are at greater risk for developing severe influenza infection and tend to have weaker responses to influenza vaccination. The purpose of this study is to understand how a child's early exposure to influenza vaccine or infection with influenza virus prepares him or her to combat future infections with this virus. Investigators will learn about how protection develops following an influenza infection or vaccination and t... Read More
Gender:
All
Ages:
Between 3 months and 15 years
Trial Updated:
07/15/2020
Locations: University of Rochester, Rochester, New York
Conditions: Influenza, Human
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