There are currently 476 clinical trials in Rochester, New York looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Rochester, University of Rochester Medical Center, James P. Wilmot Cancer Center at University of Rochester Medical Center and Rochester Clinical Research, Inc.. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study of a Behavioral Intervention for Older Advanced Cancer Patients and Their Caregivers
NCT05200572
Recruiting
The purpose of this study is to test the feasibility of a telehealth Dyadic Life Review (DLR), adapted from individual Life Review Therapy, with caregivers of older adults with advanced cancer, including those with Mild Cognitive Impairment (MCI). The study will enroll 20 dyads of caregivers and older patients with advanced cancer and 20 dyads of caregivers and patients with advanced cancer and Mild Cognitive Impairment (MCI).
Gender:
All
Ages:
50 years and above
Trial Updated:
10/30/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Cancer, Advanced, Cognitive Impairment, Mild
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Prospective, Multi-center, Single-arm, Observational Study. US FDA 522 Pediatric Post Market Surveillance Study.
NCT04608149
Recruiting
The post market surveillance study will employ a prospective, multi-center, single-arm, observational design to capture data on children who undergo CRRT using the Carpediem™ system. Participating clinicians will manage subjects in accordance to their local standard of care practices and decisions on initiating, modifying or discontinuing CRRT are up to the local investigative team's prescription. A minimum of 10 centers in the United States, that have been trained on the use of the Carpediem™... Read More
Gender:
All
Ages:
All
Trial Updated:
10/17/2023
Locations: Golisano Children's Hospital, Rochester, New York
Conditions: Acute Kidney Injury, Fluid Overload
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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: University of Rochester, Rochester, New York
Conditions: Cutaneous Melanoma, Stage II
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Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma
NCT05597345
Recruiting
Selinexor is a drug that has been approved in the treatment of patients with symptomatic multiple myeloma. The standard of care for patients with Smoldering Multiple Myeloma remains observation, but there are numerous clinical trials investigating interventions to delay progression to multiple myeloma and prevent or delay disease related outcomes. A subset of patients with intermediate or high risk smoldering multiple myeloma have a much higher risk of progressive to multiple myeloma, while the... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/13/2023
Locations: University of Rochester, Rochester, New York
Conditions: Smoldering Multiple Myeloma
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A Study of PET Adapted Therapy and Non-invasive Monitoring for Previously Untreated Limited Stage Diffuse Large B Cell Lymphoma
NCT03758989
Recruiting
The overarching goals of this study are to measure levels of circulating tumor DNA (ctDNA) in patients with early stage diffuse large B cell lymphoma (DLBCL), to assess the change in ctDNA during treatment in order to prospectively identify markers of treatment failure, and to use ctDNA as a future tool for response adapted therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: University of Rochester, Rochester, New York
Conditions: DLBCL
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Post-Approval Study of the TREO Abdominal Stent-Graft System
NCT04697784
Recruiting
The purpose of this study is to determine the long-term performance of the TREO Abdominal Stent-Graft as a treatment for patients with Infrarenal Abdominal Aortic Aneurysms or Aorto-iliac Aneurysms.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: University of Rochester -- Strong Memorial Hospital, Rochester, New York
Conditions: Abdominal Aortic Aneurysm
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Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong, Essentials for Mothers of Newborns) Delivered Using an Electronic App
NCT05518162
Recruiting
A randomized trial of pregnant people at risk for postpartum depression comparing the InBloom app (n = 76) to ROSE (n = 76; weekly scheduled group), and two control groups. We will assess Depression at baseline and 1, 2 and 3 months, ROI at 3 months, Satisfaction at 1 and 3 months and Perceived Access at 1 and 3 months. Subject participation will last up to 8 months (minimum 17 weeks pregnant through 3 months postpartum).
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/26/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Post-partum Depression
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OPN-375 Efficacy and Safety in Adolescents With Bilateral Nasal Polyps
NCT03747458
Recruiting
This is a 16-Week Randomized, Double-Blind, Placebo Controlled, Parallel-Group, Multicenter Study Evaluating the Efficacy and Safety of OPN-375 186 μg Twice a Day (BID) in Adolescents with Bilateral Nasal Polyps followed by a 12-Week Open-Label Treatment Phase. The total planned number of subjects is approximately 120 adolescents (12-17 years of age) who will be randomly assigned to receive 1 of 2 study treatments using a 2:1 ratio (OPN-375 186 μg: Placebo). For the PK sub-study, up to 14 subjec... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
09/22/2023
Locations: University of Rochester, Rochester, New York
Conditions: Bilateral Nasal Polyposis
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Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma
NCT05102721
Recruiting
This trial will assess the safety and tolerability of Pepinemab in combination with Avelumab in patients with metastatic pancreatic adenocarcinoma that has progressed after first line chemotherapy. Phase 2 will assess the efficacy of this combination therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Metastatic Pancreatic Adenocarcinoma
Register for Updates
Gene Therapy Study for Children With CLN5 Batten Disease
NCT05228145
Recruiting
This is a prospective, non-randomized, open-label, dose escalation study of a single administration of gene therapy in children who are 3 to 9 years old with Neuronal Ceroid Lipofuscinosis (Batten) Subtype 5 (CLN5) disease.
Gender:
All
Ages:
Between 3 years and 9 years
Trial Updated:
09/14/2023
Locations: University of Rochester, Rochester, New York
Conditions: Neuronal Ceroid Lipofuscinosis CLN5
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Noninterventional Study Evaluating Parkinson's Disease Diary Use
NCT05363046
Recruiting
This study aims to evaluate the impact of the frequency of assessments on the variability over time, reliability, and compliance for the Parkinson's disease (PD) diary in patients with PD in whom medications do not provide adequate control of symptoms.
Gender:
All
Ages:
Between 39 years and 70 years
Trial Updated:
09/12/2023
Locations: University of Rochester Medical Center, Rochester, New York
Conditions: Parkinson's Disease
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Consent for Use of Stored Patient Specimens for Future Testing
NCT00031408
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
All
Ages:
All
Trial Updated:
09/12/2023
Locations: Community Health Network Inc, Rochester, New York +2 locations
Conditions: HIV Infections
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