The state of North Carolina currently has 411 active clinical trials seeking participants for Cancer research studies. These trials are conducted in various cities, including Durham, Charlotte, Winston-Salem and Chapel Hill.
KM3D Multicenter Cancer Consortium: Predicting Patient Response Using 3D Cell Culture Models
Recruiting
This study will assess the ability of the Known Medicine platform to predict the efficacy of certain cancer drug treatments and to validate that tumor organoid drug sensitivity is representative of patient treatment outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/21/2023
Locations: Duke Cancer Institute, Durham, North Carolina
Conditions: Cancer, Predictive Cancer Model, Effects of Chemotherapy
Gedatolisib Plus Fulvestrant With or Without Palbociclib vs Standard-of-Care for the Treatment of Patients With Advanced or Metastatic HR+/HER2- Breast Cancer
Recruiting
This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant with or without palbociclib for the treatment of patients with locally advanced or metastatic HR+/HER2- breast cancer following progression on or after CDK4/6 and aromatase inhibitor therapy. Condition or disease: Breast Cancer Intervention/treatment: Drug: Gedatolisib Drug: Palbociclib Drug: Fulvestrant Drug: Alpelisib Phase 3
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2022
Locations: Cone Health Cancer Center at Alamance Regional, Hematology/Oncology, Greensboro, North Carolina
Conditions: Breast Cancer
Caris Biorepository Research Protocol
Recruiting
The Biorepository for Caris Life Sciences is designed for the purpose of making quality biospecimens and associated clinical data available for research studies related to advancing precision medicine and improving care for patients. The Caris Biorepository is a repository of prospectively collected biological specimens and associated clinical and demographic data gathered from multiple sources to be stored, used and shared for research. Caris Life Sciences will maintain the data and specimens... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/21/2020
Locations: Eastern Carolina Women's Center, New Bern, North Carolina
Conditions: Cancer