There are currently 50 active clinical trials seeking participants for Chronic Kidney Diseases research studies. The states with the highest number of trials for Chronic Kidney Diseases participants are California, Florida, Texas and North Carolina.
Anti-Inflammatory Treatment of Uremic Cardiomyopathy With Colchicine
NCT04500665
Recruiting
This study is designed to determine the efficacy and safety of colchicine in patients with chronic kidney disease.
Gender:
All
Ages:
Between 21 years and 80 years
Trial Updated:
06/18/2024
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Chronic Kidney Diseases
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A Study to Evaluate TOUR006 in Patients With Chronic Kidney Disease and Elevated Hs-CRP
NCT06362759
Recruiting
This study will evaluate the safety, tolerability, pharmacokinetics, and CRP-lowering effect of quarterly and monthly subcutaneous administration of TOUR006 in participants with chronic kidney disease and elevated hs-CRP.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2024
Locations: Site - 0101, Birmingham, Alabama +15 locations
Conditions: Chronic Kidney Diseases, Chronic Kidney Insufficiency, Chronic Renal Diseases, Chronic Renal Insufficiency, Kidney Insufficiency, Chronic, C-Reactive Protein, High Sensitivity C-Reactive Protein, Hs-CRP, hsCRP
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Improving the Collaborative Health of Minority COVID-19 Survivor and Carepartner Dyads
NCT05370014
Recruiting
This study tests the efficacy of a dyadic intervention to mitigate the adverse health consequences of severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2 )(COVID-19) in African American (AA) adults with pre-existing chronic health conditions and their informal carepartners (IC). Socioeconomically disadvantaged, older, and Black/African American from rural regions are burdened with greater rates of chronic diseases such as diabetes, hypertension, chronic kidney disease, cardiovascular di... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: University of South Carolina, Columbia, South Carolina
Conditions: SARS- CoV-2, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus, Type 2, Chronic Disease, Stroke
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A Study of REACT in Subjects With Type 2 Diabetes Mellitus and Chronic Kidney Disease
NCT05099770
Recruiting
The purpose of this study is to assess the safety and efficacy (including durability) of up to 2 REACT injections given 3 months (+30 days) apart and delivered percutaneously into biopsied and non-biopsied contralateral kidneys in participants with T2DM and CKD.
Gender:
All
Ages:
Between 30 years and 80 years
Trial Updated:
06/10/2024
Locations: Paradise Clinical Research Group LLC, Glendora, California +45 locations
Conditions: Type 2 Diabetes Mellitus, Chronic Kidney Diseases
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/07/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +83 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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Home-based Conservative Care Model for Advanced Kidney Disease
NCT06411613
Recruiting
This is a randomized pilot study to test the feasibility and acceptability of a novel conservative care (CC) pathway among patients with advanced chronic kidney disease (CKD) who have chosen to forgo initiation of maintenance dialysis, their caregivers and providers.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington
Conditions: Chronic Kidney Diseases
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Pregnancy and Contraception Education in Chronic Kidney Disease (PACE-CKD)
NCT06189807
Recruiting
This pilot study will assess the efficacy of a pregnancy and contraception education decision aid (DA) for patients with chronic kidney disease to support decisions about reproductive health, and will assess feasibility and acceptability of the intervention to inform future Research Project Grant (R01) level studies.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
05/28/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: CKD, Chronic Kidney Diseases
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Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients
NCT03471117
Recruiting
Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular disease and death. An overactive sympathetic nervous system in CKD patients is one of the major mechanisms increasing the cardiovascular risks in this patient population. Recently, some studies have shown that a drug typically used to improve glucose control (pioglitazone) may also reduce sympathetic nerve activity and improve blood vessel function. The goal of this study is to determine whether a short-term treatme... Read More
Gender:
All
Ages:
Between 35 years and 70 years
Trial Updated:
05/22/2024
Locations: University of Texas at Arlington, Arlington, Texas +1 locations
Conditions: Chronic Kidney Diseases
Register for Updates
Sodium Bicarbonate and Mitochondrial Energetics in Persons With CKD
NCT04984226
Recruiting
Skeletal muscle metabolic health is critical for mobility and an underrecognized target of metabolic acidosis in chronic kidney disease. Impaired muscle mitochondrial metabolism underlies poor physical endurance increasing the risk of mobility disability. The proposed project will use precise in vivo tools to study the pathophysiology of poor physical endurance in a clinical trial treating metabolic acidosis among persons living with chronic kidney disease.
Gender:
All
Ages:
Between 21 years and 85 years
Trial Updated:
05/16/2024
Locations: University of California Davis Health, Sacramento, California +1 locations
Conditions: Chronic Kidney Diseases, Metabolic Acidosis, Fatigue, Physical Endurance, Insulin Resistance, Mitochondrial Energetics, Diabetes
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Ferric Citrate and Chronic Kidney Disease in Children
NCT04741646
Recruiting
We will conduct a 12-month, double-blind, randomized, placebo-controlled trial to assess the effects of therapy with ferric citrate (FC) on changes in intact FGF23 levels (iFGF23, primary endpoint) in 160 pediatric patients (80 in each of the two arms) aged 6-18 years of either sex with chronic kidney disease (CKD) stages 3-4 and age-appropriate normal serum phosphate levels. Participants will be randomized to one of the two groups: 1) FC or 2) FC placebo. Participants will be recruited from 12... Read More
Gender:
All
Ages:
Between 6 years and 18 years
Trial Updated:
05/10/2024
Locations: University of California, Los Angeles, Los Angeles, California +11 locations
Conditions: Chronic Kidney Diseases
Register for Updates
Bone in CKD Alkali Response (BICARb Pilot Trial)
NCT05918029
Recruiting
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease. The main questions it aims to answer are: To evaluate effects of potassium citrate treatment on bone quality and strength. To evaluate mechanism(s) underlying the effects of potassium citrate on skeletal health. Participants will be asked to: provide blood, urine and answer questions about health and diet three times during an 8 months period underg... Read More
Gender:
All
Ages:
Between 5 years and 100 years
Trial Updated:
05/07/2024
Locations: Albert Einstein College of Medicine, Bronx, New York +1 locations
Conditions: Chronic Kidney Diseases, Bone Loss
Register for Updates
Cerebrovascular Dysregulation in Chronic Kidney Disease
NCT05571605
Recruiting
The purpose of this study is to test whether or not regular exercise training may improve brain blood flow regulation in patients with chronic kidney disease (CKD).
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
05/06/2024
Locations: University of North Texas, Denton, Texas
Conditions: Chronic Kidney Diseases
Register for Updates