The city of Cleveland, Ohio, currently has 3 active clinical trials seeking participants for Alzheimer's Disease research studies.
CONFIDENCE-AI Financial Education for Caregivers (CONFIDENCE-AI)
NCT06134180
Recruiting
The intervention being tested, CONFIDENCE-AI is a refined version of the original CONFIDENCE intervention made to reduce psychological financial strain and improve management of out-of-pocket care costs while increasing caregiver resourcefulness skills. Participants will be asked to participate in a 4-week intervention that includes participation in four, synchronous group-based Zoom sessions as well as between-session activities to apply learning. Participants will also receive tailored text me... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/23/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Alzheimer Disease, Dementia, Caregiver Burden, Financial Stress
Register for Updates
AHEAD 3-45 Study: A Study to Evaluate Efficacy and Safety of Treatment With Lecanemab in Participants With Preclinical Alzheimer's Disease and Elevated Amyloid and Also in Participants With Early Preclinical Alzheimer's Disease and Intermediate Amyloid
NCT04468659
Recruiting
The primary purpose of this study is to determine whether treatment with lecanemab is superior to placebo on change from baseline of the Preclinical Alzheimer Cognitive Composite 5 (PACC5) at 216 weeks of treatment (A45 Trial) and to determine whether treatment with lecanemab is superior to placebo in reducing brain amyloid accumulation as measured by amyloid positron emission tomography (PET) at 216 weeks of treatment (A3 Trial). This study will also evaluate the long-term safety and tolerabili... Read More
Gender:
All
Ages:
Between 55 years and 80 years
Trial Updated:
02/06/2024
Locations: Cleveland Clinic Lou Ruvo Center for Brain Health, Cleveland, Ohio
Conditions: Preclinical Alzheimer's Disease, Early Preclinical Alzheimer's Disease
Register for Updates
Learning Skills Together Family Caregiver Complex Intervention
NCT05846984
Recruiting
Learning Skills Together (LST) is a 6-week psychoeducational intervention focused on complex care (nursing) tasks completed by family caregivers to persons living with Alzheimer's Disease and related dementias. This study aims to test the efficacy of LST at reducing caregiver depression and negative appraisal of behavioral symptoms of dementia by building caregiver self-efficacy. To do this, eligible participants will be randomized into an intervention group (LST) or a control group condition fo... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Case Western Reserve University, Cleveland, Ohio
Conditions: Dementia, Alzheimer Disease, Caregiver Burden, Self Efficacy
Register for Updates