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Type 2 Diabetes Clinical Trials in Cleveland, OH
A listing of 6 Type 2 Diabetes clinical trials in Cleveland, OH actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 6 of 6
The city of Cleveland, Ohio, currently has 6 active clinical trials seeking participants for Type 2 Diabetes research studies.
Featured Trial
New High Blood Pressure (Hypertension) Clinical Trials
Recruiting
This campaign features 7 hypertension studies for adults with high blood pressure that remains uncontrolled despite medication. Studies are available for a range of cardiovascular profiles, including people taking multiple blood pressure medications or living with heart or vascular disease.
Inclusion Criteria:
- Diagnosed with high blood pressure (hypertension)
- Age 18+ (one study requires participants to be 55+)
- Blood pressure remains elevated despite taking medication (typically systolic 135 mmHg or higher), or your doctor has expressed concerns about your blood pressure
- Currently taking 2 or more blood pressure medications
- Have cardiovascular disease (such as a previous heart attack, coronary artery disease, stroke, or peripheral artery disease) or certain cardiovascular risk factors, including diabetes, chronic kidney disease (CKD), atrial fibrillation (AF), or smoking (study dependent)
- Stable body weight for the past 3 months
Find out if you qualify today.
Inclusion Criteria:
- Diagnosed with high blood pressure (hypertension)
- Age 18+ (one study requires participants to be 55+)
- Blood pressure remains elevated despite taking medication (typically systolic 135 mmHg or higher), or your doctor has expressed concerns about your blood pressure
- Currently taking 2 or more blood pressure medications
- Have cardiovascular disease (such as a previous heart attack, coronary artery disease, stroke, or peripheral artery disease) or certain cardiovascular risk factors, including diabetes, chronic kidney disease (CKD), atrial fibrillation (AF), or smoking (study dependent)
- Stable body weight for the past 3 months
Find out if you qualify today.
Conditions:
Hypertension Multi
Hypertension
Pulmonary Hypertension
Ocular Hypertension
Pulmonary Arterial Hypertension
Featured Trial
New Obesity Clinical Studies Now Recruiting
Recruiting
We are seeking participants for multiple clinical trials focused on obesity and metabolic health, evaluating investigational treatments for weight management and diabetes. Studies are looking for adults with obesity, with or without type 2 diabetes, who are not currently taking GLP-1 medications or other weight-loss treatments.
See if you qualify today.
See if you qualify today.
Conditions:
Obesity Multi
Obesity
Overweight and Obesity
Morbid Obesity
Childhood Obesity
Featured Trial
Multiple Type 2 Diabetes Studies Now Recruiting
Recruiting
We are seeking participants for 14 clinical studies investigating new treatments for type 2 diabetes (T2DM) and related conditions including obesity and fatty liver disease (MASH/NAFLD). Studies are looking for adults with a confirmed T2DM diagnosis who are not well-controlled or are seeking improved management, spanning a range of disease stages from early/diet-managed to long-standing and multiply medicated.
See if you qualify today.
See if you qualify today.
Conditions:
Type 2 Diabetes Multi
Type 2 Diabetes
Diabete Type 2
Diabetic Nephropathy Type 2
Type 2 Diabetes Mellitus
Featured Trial
Reduce Heart Failure Risk – See if You Qualify for a Study
Recruiting
We are currently looking for individuals aged 18 and older to take part in a heart disease research study. You may be eligible if you have been diagnosed with all of the following:
• Cardiovascular Disease
• Type 2 Diabetes
• High Blood Pressure
This study is exploring an investigational medication that may help reduce the risk of heart-related complications.
If you’re interested in learning more, you can see if you pre-qualify today.
• Cardiovascular Disease
• Type 2 Diabetes
• High Blood Pressure
This study is exploring an investigational medication that may help reduce the risk of heart-related complications.
If you’re interested in learning more, you can see if you pre-qualify today.
Conditions:
Heart Diseases
Congenital Heart Disease
Coronary Heart Disease
Ischemic Heart Disease
Heart Disease
Featured Trial
Now Recruiting: Cardiovascular Disease (CVD) Clinical Studies
Recruiting
We are seeking participants for 31 cardiovascular disease (CVD) studies covering conditions such as high blood pressure (hypertension), atherosclerotic heart disease, high cholesterol (hyperlipidemia), heart failure, and type 2 diabetes with CVD. The studies are recruiting adults ages 18 and older who have been diagnosed with one or more of these conditions and are currently receiving treatment.
See if you qualify today.
See if you qualify today.
Conditions:
CVD Multi
CVD
Cardiovascular Disease
Cardiovascular Diseases
High Blood Pressure
Featured Therapy
Unique Treatment for High Blood Pressure
Worried about high blood pressure? Think beyond typical high blood pressure treatments.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
People who may be candidates for this procedure:
• Are at least 18 years old
• Have been unable to manage their high blood pressure with medications or lifestyle changes alone¹
Learn about a safe and effective procedure that may help reduce high blood pressure. See if you qualify today.
¹ Kandzari DE, et al. J Am Coll Cardiol. Nov 7, 2023;82(19):1809-1823.
Conditions:
High Blood Pressure
High Blood Pressure (& [Essential Hypertension])
High Blood Pressure (Hypertension).
Hypertension
Essential Hypertension
Effect of Retatrutide Compared With Placebo in Participants With Type 2 Diabetes and Moderate or Severe Renal Impairment, With Inadequate Glycemic Control on Basal Insulin, With or Without Metformin and/or SGLT2 Inhibitor (TRANSCEND-T2D-3)
Recruiting
The purpose of this study is to investigate the efficacy and safety of retatrutide compared with placebo in participants with Type 2 Diabetes and renal impairment, with inadequate glycemic control on basal insulin alone or a combination of basal insulin with or without metformin and/or sodium-glucose cotransporter-2 (SGLT2) inhibitor. The study will last about 14 months and may include up to 22 visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/22/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Type 2 Diabetes
A Study of Dulaglutide (LY2189265) 3.0 mg and 4.5 mg in Pediatric Participants With Type 2 Diabetes Mellitus (AWARD-PEDS PLUS)
Recruiting
The main purpose of this study is to evaluate additional dosing options for dulaglutide in pediatric participants with Type 2 Diabetes. Participation in this study will last about 8 months.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
07/22/2025
Locations: Cleveland Clinic Childrens Outpatient Center, Cleveland, Ohio
Conditions: Type 2 Diabetes
Continuous Glucose Metrics in Patients With Gastroparesis in Type 1 or Type 2 Diabetes
Recruiting
A pilot study to evaluate and compare glucose metrics using a real-time continuous glucose monitor (FreeStyle Libre 3 sensor) between patients with diabetes and gastroparesis and those with diabetes without gastroparesis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Diabetes Mellitus, Type 2, Diabetes Mellitus, Type 1, Gastroparesis With Diabetes Mellitus
Glycemic Control, Type II Diabetes, Parathyroidectomy
Recruiting
The purpose of this study is to assess glycemic control after parathyroidectomy in patients with primary hyperparathyroidism and concomitant type 2 diabetes mellitus.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/19/2025
Locations: Cleveland Clinic Main Campus, Cleveland, Ohio
Conditions: Primary Hyperparathyroidism, Type 2 Diabetes
Holding vs. Continuing Incretin-based Therapies Before Upper Endoscopy
Recruiting
To assess whether holding incretin-based therapy before endoscopy reduces the likelihood of clinically relevant Residual Gastric Volume (RGV).
Primary Outcomes:
* Residual gastric volume that precludes adequate endoscopic examination
* Residual gastric volume that necessitates premature termination of the endoscopy procedure
* Need for endotracheal intubation due to stomach contents.
* Occurrence of aspiration events requiring extended observation/monitoring, unplanned therapeutics, and/or hos... Read More
Gender:
ALL
Ages:
All
Trial Updated:
02/17/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Diabetes Mellitus, Type 2, Obesity, Gastroparesis
RESET System Pivotal Trial (Rev F)
Recruiting
A Randomized, Multi-Center, Pivotal Efficacy and Safety Study Evaluating the RESET System for Glycemic Improvement in Patients with Inadequately Controlled Type 2 Diabetes and Obesity, the STEP-1 Study.
A multi-center, double-blinded, randomized, sham-controlled trial to evaluate the safety and effectiveness of the RESET System plus moderate intensity lifestyle and dietary counseling compliant with 2024 ADA Standard of Care as compared to a sham control receiving moderate intensity lifestyle an... Read More
Gender:
ALL
Ages:
Between 22 years and 65 years
Trial Updated:
07/16/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Diabetes type2, Obesity
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