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Aortic Stenosis Clinical Trials
A listing of 14 Aortic Stenosis clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 14
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There are currently 14 active clinical trials seeking participants for Aortic Stenosis research studies. The states with the highest number of trials for Aortic Stenosis participants are California, New York, Texas and Ohio.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Clinical Study
Recruiting
We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.
Conditions:
Cough
Chronic Cough
Asthma
Allergic Asthma
Sinusitis
Featured Trial
Transcranial Magnetic Stimulation (TMS) for Obsessive Compulsive Disorder (OCD)
Recruiting
Transcranial magnetic stimulation (TMS) is an FDA-approved, non-invasive form of brain stimulation for OCD. TMS has been shown to be an effective form of treatment in individuals with OCD. By using a form of TMS termed theta-burst stimulation (TBS), we hope that this will result in a more effective treatment by producing faster symptom reduction. We are trialing a novel form of accelerated TMS, where we will deliver ten 10-minute sessions per day, for 5 days. This study will compare the efficacy of TMS for OCD at two distinct brain regions. Participants will be randomized into one of two study groups, and receive stimulation at either the DMPFC or R-OFC. Both regions have been linked to OCD by research. Patients that don't respond to their study region will have the option to receive stimulation at the other region.
Conditions:
Obsessive-Compulsive Disorder
Obsessive Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Obsessive-Compulsive Disorder (OCD)
Obsessive-compulsive Disorders and Symptoms
Featured Trial
High Triglyceride Clinical Research Study
Recruiting
Living with high triglycerides? See if our clinical study is right for you.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Don’t let financial stress hold you back. All clinical study-related assessments, care, and the investigational study drug are available at no cost. You could also be eligible for compensation for travel.
Conditions:
High Triglycerides
High Triglyceride Level
Hypertriglyceridemia
Elevated Triglycerides
Triglycerides High
Novel Characterization of Sex Specific Biologic Signatures in Valvular Heart Disease
Recruiting
This project aims to validate sex-specific biologic signatures associated with aortic valve disease developed in a large multicenter CMR registry, using unsupervised phenomapping.
We aim to use advanced CMR techniques (MRF, DTI, chemical exchange transfer, and radiomics analysis) to determine advanced CMR predictors of reverse remodeling following aortic valve surgery and develop sex-specific thresholds for risk. Infrastructure developed by this study will enable development of an innovative, s... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
01/13/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Aortic Regurgitation, Mitral Regurgitation, Aortic Stenosis
Comparative Imaging Assessment of Valvular Heart Disease
Recruiting
The purpose of the study is to compare the various 2D and 3D methods of valvular heart disease quantification (Doppler, PISA, VCA, volumetric method) and strain with cardiac magnetic resonance (CMR) measurements of left and right ventricular systolic function strain and myocardial fibrosis assessment.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
12/19/2024
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Valve Heart Disease, Aortic Stenosis, Aortic Regurgitation
REdo tranScatheter Aortic Valve Replacement for Transcatheter aOrtic Valve failuRE
Recruiting
The purpose of this study is to generate clinical evidence on valve safety and performance in subjects treated by redo Transcatheter Aortic Valve Replacement (TAVR).
Gender:
ALL
Ages:
Between 18 years and 105 years
Trial Updated:
02/03/2025
Locations: Morton Plant Hospital, Clearwater, Florida +3 locations
Conditions: Aortic Stenosis
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Recruiting
The purpose of this study is to evaluate the efficacy, safety and tolerability of pelacarsen (TQJ230) administered subcutaneously once monthly compared to placebo in slowing the progression of calcific aortic valve stenosis.
Gender:
ALL
Ages:
Between 50 years and 80 years
Trial Updated:
01/22/2025
Locations: Heart Center Research Llc, Huntsville, Alabama +93 locations
Conditions: Aortic Stenosis
AI in Outpatient Practice for Diagnosing Aortic Stenosis and Diastolic Dysfunction
Recruiting
Two recently developed artificial intelligence-enabled electrocardiogram (AI-ECG) models have been developed to detect aortic stenosis (AS) and diastolic dysfunction (DD). AI-ECG for AS has a sensitivity of 78% and specificity of 74%, and AI-ECG for DD has a sensitivity of 83% and specificity of 80%. However, these models have never been prospectively applied to diagnose AS or DD, which may be useful for patients and providers from a diagnostic and prognostic perspective and especially in settin... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
12/30/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Aortic Stenosis, Diastolic Dysfunction
Long Term Evaluation of Cardiac Arrhythmias After Transcatheter Aortic Valve Implantation -The LOCATE Registry
Recruiting
The purpose of the Long term Evaluation of Cardiac Arrhythmias after Transcatheter Aortic Valve Implantation (LOCATE) Registry is to perform long-term ambulatory monitoring of patients with severe aortic stenosis who undergo trans-catheter aortic valve implantation (TAVI) and develop new onset conduction system abnormalities post-procedure that do not require urgent permanent pacemaker (PPM) implantation. The primary objectives of this study are to assess the incidence of late onset heart block... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: Research Medical Center Clinic, Kansas City, Missouri +1 locations
Conditions: Aortic Stenosis, Atrial Fibrillation New Onset, Heart Block
Loss of Y Chromosome in Aortic Stenosis
Recruiting
The most common heart valve disease in humans is aortic stenosis which is a critical narrowing of the valve through which the heart has to pump blood to the rest of the body. This condition occurs in 2-3% of adults over 65 years of age and when it progresses to a severe stage leads to heart failure and need for valve replacement procedures (including surgery and catheter-based replacement). Aortic stenosis has a strong male predominance. The purpose of this study is to evaluate whether loss of Y... Read More
Gender:
MALE
Ages:
40 years and above
Trial Updated:
09/10/2024
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Aortic Stenosis
PARTNER 3 Trial - Aortic Valve-in-Valve
Recruiting
This study will assess the safety and effectiveness of the SAPIEN 3/SAPIEN 3 Ultra transcatheter heart valve (THV) in patients with a failing aortic bioprosthetic valve.
Gender:
All
Ages:
All
Trial Updated:
05/08/2024
Locations: Banner University Medical Center, Phoenix, Arizona +50 locations
Conditions: Aortic Stenosis, Aortic Stenosis, Severe
Evaluating Infrasonic Hemodynography
Recruiting
This comparative diagnostic accuracy study will determine the accuracy of a noninvasive wearable infrasonic sensor to detect the mechanical, electrical, and hemodynamic function of the cardiovascular system.
Gender:
All
Ages:
All
Trial Updated:
04/15/2024
Locations: Scripps Health, La Jolla, California
Conditions: Aortic Stenosis, Mitral Regurgitation, Pulmonary Hypertension, Heart Failure, Systolic, Cardiovascular Diseases, Coronary Artery Disease
Staged Complete Revascularization for Coronary Artery Disease vs Medical Management Alone in Patients With AS Undergoing Transcatheter Aortic Valve Replacement
Recruiting
Patients undergoing transcatheter aortic valve replacement (TAVR) often have concomitant coronary artery disease (CAD) which may adversely affect prognosis. There is uncertainty about the benefits and the optimal timing of revascularization for such patients. There is currently clinical equipoise regarding the management of concomitant CAD in patients undergoing TAVR. Some centers perform routine revascularization with percutaneous coronary intervention (PCI) (either before or after TAVR), while... Read More
Gender:
All
Ages:
All
Trial Updated:
12/13/2023
Locations: Huntsville Heart Center, Huntsville, Alabama +71 locations
Conditions: Aortic Stenosis, Coronary Artery Disease, Coronary Stenosis
Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR (DISCORDANCE TAVR)
Recruiting
The DISCORDANCE TAVR study will determine the discordance between echocardiography-derived and invasive transaortic gradients, as determined by a consistent and reproducible technique (Standardized Invasive Hemodynamics) post-TAVR.
Gender:
All
Ages:
All
Trial Updated:
06/06/2023
Locations: PIMA Heart Centre, Tucson, Arizona +9 locations
Conditions: Aortic Stenosis, Aortic Valve Stenosis
Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
Recruiting
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2022
Locations: Baylor Heart and Vascular Hospital, Dallas, Texas +3 locations
Conditions: Mild Cognitive Impairment, Aortic Stenosis
1 - 12 of 14