There are currently 237 clinical trials in Dayton, Ohio looking for participants to engage in research studies. Trials are conducted at various facilities, including Miami Valley Hospital, Grandview Hospital, Miami Valley Hospital North and CCOP - Dayton. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Testing the Effects of Exercise on Chemotherapy-Induced Peripheral Neuropathy
NCT04888988
Recruiting
This phase II trial studies whether using exercise is better than the usual approach for treating chemotherapy-induced peripheral neuropathy (CIPN). CIPN occurs when chemotherapy damages the nerves communicating between the brain, spinal cord, and the rest of the body. The usual approach for treating CIPN is treatment with drugs that help reduce symptoms of other types of neuropathy (for example, from diabetes). However, these drugs do not treat all symptoms of CIPN. Exercise may help to reduce... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/02/2024
Locations: Dayton Clinical Oncology Program, Dayton, Ohio
Conditions: Chemotherapy-Induced Peripheral Neuropathy
Register for Updates
Exparel and Education to Avoid Opioids After Carpal Tunnel Release
NCT03867539
Recruiting
This trial seeks to use the long acting local anesthetic Exparel, in conjunction with opioid education, to attempt to avoid any post-operative opioid use following carpal tunnel surgery. This group will be compared with a "standard" group that receives non-liposomal bupivacaine, opioid education, and opioids.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/26/2024
Locations: Orthopedic Associates of Southwest Ohio, Dayton, Ohio +1 locations
Conditions: Carpal Tunnel Syndrome
Register for Updates
Pilot Study Evaluating the Elasticity and Shear Wave Modulus (Stiffness) of the Median Nerve in Patients With Mild to Moderate Idiopathic Carpal Tunnel Syndrome Receiving OMT and Conservative Therapy
NCT06150443
Recruiting
To evaluate and quantify changes in the elasticity and shear wave modulus (stiffness) of the median nerve in patients diagnosed with mild to moderate carpal tunnel syndrome following osteopathic manipulative therapy.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/25/2024
Locations: Kettering Health, Dayton, Ohio
Conditions: Carpal Tunnel Syndrome
Register for Updates
A Study of Efficacy and Safety of Ianalumab in Previously Treated Patients With Warm Autoimmune Hemolytic Anemia
NCT05648968
Recruiting
The purpose of this study is to evaluate efficacy and safety of ianalumab compared to placebo in patients with warm autoimmune hemolytic anemia, who failed at least one line of treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: STAT Research Inc Premier Clin Res LLC STAT Res, Dayton, Ohio
Conditions: Warm Autoimmune Hemolytic Anemia (wAIHA)
Register for Updates
Study of Ianalumab Versus Placebo in Addition to First-line Corticosteroids in Primary Immune Thrombocytopenia (ITP)
NCT05653349
Recruiting
The purpose of this study is to evaluate the effect of two different doses of ianalumab versus placebo in addition to first-line corticosteroids in maintaining platelet count ≥30 G/L in adult participants with primary ITP.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/22/2024
Locations: STAT Research Inc Premier Clin Res LLC STAT Res, Dayton, Ohio
Conditions: Primary Immune Thrombocytopenia (ITP)
Register for Updates
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
NCT05324358
Recruiting
This clinical study is a randomized, double-blind, double-dummy, parallel group, multi-center, active and placebo-controlled trial evaluating the analgesic efficacy and safety of NTM-001 in subjects with moderately severe postoperative pain after bunionectomy surgery. This study is designed to compare the efficacy of NTM-001 to placebo. Intravenous (IV) morphine serves as an active comparator to determine assay sensitivity and support assessment of opioid-level analgesia for NTM-001. Effectiven... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/19/2024
Locations: Midwest Clinical Research Center, Dayton, Ohio
Conditions: Pain, Postoperative
Register for Updates
Registry of Participants With Generalized Myasthenia Gravis Treated With Alexion C5 Inhibition Therapies (C5ITs)
NCT04202341
Recruiting
Long-term, multicenter, multinational, observational, registry of patients with gMG that is designed to collect data on clinical outcomes and safety in patients prescribed Alexion C5 inhibitor therapies (C5IT) such as eculizumab (Soliris®) and ravulizumab (Ultomiris®).
Gender:
All
Ages:
All
Trial Updated:
03/15/2024
Locations: Clinical Trial Site, Dayton, Ohio
Conditions: Generalized Myasthenia Gravis
Register for Updates
The Purpose of This Study is to Evaluate the Effects of Ruxolitinib Cream on Adults With Atopic Dermatitis Experiencing Sleep Disturbance.
NCT05696392
Recruiting
The purpose of the study is to evaluate the effect of ruxolitinib cream on sleep disturbances with participants with Atopic Dermatitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/13/2024
Locations: Ohio Pediatric Research Association, Dayton, Ohio
Conditions: Atopic Dermatitis
Register for Updates
Evaluation of the RD-X19 Treatment Device in Individuals With Mild COVID-19
NCT05817045
Recruiting
This is a randomized, double-blind, sham controlled, stratified, pivotal efficacy and safety study of the EmitBio RD-X19 treatment device in Individuals 40 Years of age and older with Mild COVID-19 in the at-home setting.
Gender:
All
Ages:
40 years and above
Trial Updated:
03/11/2024
Locations: 303 - WellNow - Huber Heights, Dayton, Ohio
Conditions: COVID-19
Register for Updates
Testing the Addition of Stereotactic Radiation Therapy With Immune Therapy for the Treatment of Patients With Unresectable or Metastatic Renal Cell Cancer, SAMURAI Study
NCT05327686
Recruiting
This phase II trial tests whether the addition of radiation to the primary tumor, typically given with stereotactic ablative radiation therapy (SABR), in combination with standard of care immunotherapy improves outcomes in patients with renal cell cancer that is not recommended for surgery and has spread to other places in the body (metastatic). Radiation therapy uses high energy photons to kill tumor cells and shrink tumors. Stereotactic body radiation therapy uses special equipment to position... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Dayton Blood and Cancer Center, Dayton, Ohio +3 locations
Conditions: Metastatic Renal Cell Carcinoma, Stage III Renal Cell Cancer AJCC v8, Stage IV Renal Cell Cancer AJCC v8, Unresectable Renal Cell Carcinoma
Register for Updates
Intravesical BCG vs GEMDOCE in NMIBC
NCT05538663
Recruiting
The study hypothesis is that BCG naïve non-muscle invasive bladder cancer (NMIBC) patients treated with intravesical Gemcitabine + Docetaxel (GEMDOCE) will result in a non-inferior event-free survival (EFS) compared to standard treatment with intravesical BCG. The purpose of this study is to test whether Gemcitabine + Docetaxel is a better or worse treatment than the usual BCG therapy approach. The primary objective of this study is to determine the event free survival (EFS) of BCG-naïve high gr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/08/2024
Locations: Dayton Physician LLC-Miami Valley Hospital North, Dayton, Ohio
Conditions: Non-muscle-invasive Bladder Cancer
Register for Updates
Understanding the Long-term Impact of COVID on Children and Families
NCT05172011
Recruiting
This is a combined retrospective and prospective, longitudinal, observational meta-cohort of individuals age 0-25 years who will enter the cohort with and without SARS-CoV-2 infection at varying stages before and after infection. Individuals with and without SARS-CoV-2 infection and with or without PASC symptoms will be followed to identify risk factors and occurrence of PASC. This study will be conducted in the United States and participants will be recruited through inpatient, outpatient, and... Read More
Gender:
All
Ages:
25 years and below
Trial Updated:
03/04/2024
Locations: Miami Valley Hospital, Dayton, Ohio
Conditions: SARS-CoV-2 Infection
Register for Updates