The city of Dayton, Ohio, currently has 6 active clinical trials seeking participants for Pain research studies.
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
NCT05986292
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/03/2024
Locations: META Medical Research Institute, Dayton, Ohio
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
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Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
NCT05324358
Recruiting
This clinical study is a randomized, double-blind, double-dummy, parallel group, multi-center, active and placebo-controlled trial evaluating the analgesic efficacy and safety of NTM-001 in subjects with moderately severe postoperative pain after bunionectomy surgery. This study is designed to compare the efficacy of NTM-001 to placebo. Intravenous (IV) morphine serves as an active comparator to determine assay sensitivity and support assessment of opioid-level analgesia for NTM-001. Effectiven... Read More
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
03/19/2024
Locations: Midwest Clinical Research Center, Dayton, Ohio
Conditions: Pain, Postoperative
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Evaluation of Efficacy and Safety of VX-548 for Painful Lumbosacral Radiculopathy (PLSR)
NCT06176196
Recruiting
The purpose of the study is to evaluate the efficacy and safety of VX-548 in treating participants with PLSR.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/06/2024
Locations: META Medical Research Institute, Dayton, Ohio
Conditions: Painful Lumbosacral Radiculopathy
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Freedom-1 Study for Chronic Knee Pain
NCT03877653
Recruiting
To demonstrate the potential benefits and risk of active sub-threshold stimulation in the treatment of chronic knee pain as compared to subjects that did not have active stimulation. Improvement will be assessed in relation to the clinical outcome measures of pain, with primary endpoint; Pain relief rate as measured by the number of subjects with greater or equal to a 50% decrease in pain on the visual analog scale, comparing baseline to the 1-month follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Orthopedic Associates of Southwest Ohio, Dayton, Ohio
Conditions: Osteoarthritic Knee Pain
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XG005 for Pain Control in Subjects Undergoing Bunionectomy
NCT06017999
Recruiting
This study will evaluate the safety, efficacy, and PK of low dose (750 mg) and high-dose (1250 mg) XG005 oral tablets compared with placebo in subjects undergoing bunionectomy. Subjects will be confined in the clinic from check-in through 72 hours post-surgery to monitor subject safety.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
12/08/2023
Locations: Midwest Clinical Research Center, Dayton, Ohio
Conditions: Acute Pain
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Comparison of Qutenza (8% Capsaicin) With a Low-dose Capsaicin for Treatment of Nerve Pain After Surgery
NCT04967664
Recruiting
This is an interventional, Phase III, double-blind, randomized, controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of repeated topical application of Qutenza (capsaicin 8% topical system) versus low-dose capsaicin control (capsaicin 0.04% topical system) in subjects with moderate to severe postsurgical neuropathic pain (PSNP).
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: META Medical Research Institute, LLC, Dayton, Ohio
Conditions: Post Surgical Neuropathic Pain
Register for Updates