There are currently 228 clinical trials in Toledo, Ohio looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Toledo, Toledo Hospital, Toledo Clinic Cancer Centers-Toledo and ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Clevidipine Infusion for Blood Pressure Management After Successful Revascularization in Acute Ischemic Stroke
NCT05175547
Recruiting
The CLEVER Study is a prospective, 2-arm, randomized, single-center pilot study to assess the safety and efficacy of intensive blood pressure control using Clevidipine (on-label use) in AIS patients undergoing standard of care mechanical thrombectomy (MT) within 24-hours of symptoms onset.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2023
Locations: ProMeedica Toledo Hospital, Toledo, Ohio
Conditions: Stroke, Acute, Blood Pressure, Mechanical Thrombectomy
Register for Updates
DPX-Survivac and Pembrolizumab With and Without Intermittent Low-Dose Cyclophosphamide, in Subjects With Relapsed/Refractory Diffuse Large B-Cell Lymphoma
NCT04920617
Recruiting
This is a Phase 2b, randomized, open label study to assess the safety and efficacy of DPX-Survivac and pembrolizumab, with and without low-dose cyclophosphamide (CPA) in subjects with relapsed or refractory DLBCL.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/05/2023
Locations: University of Toledo Medical Center, Toledo, Ohio +1 locations
Conditions: Relapsed Diffuse Large B-cell Lymphoma, Refractory Diffuse Large B-cell Lymphoma
Register for Updates
The Hancock Jaffe Surgical Antireflux Venous Valve Endoprosthesis Study
NCT04943172
Recruiting
A prospective, non blinded, single arm, multicenter study designed to assess the safety and effectiveness of the bioprosthetic, VenoValve, which is surgically implanted into the deep venous system for treatment of patients with deep venous valvular insufficiency ( C4b-C6 patients).
Gender:
All
Ages:
18 years and above
Trial Updated:
04/04/2023
Locations: Jobst Vascular Institute / Promedica Toledo Hospital, Toledo, Ohio
Conditions: Deep Venous Insufficiency (Diagnosis)
Register for Updates
LCH-IV, International Collaborative Treatment Protocol for Children and Adolescents With Langerhans Cell Histiocytosis
NCT02205762
Recruiting
The LCH-IV is an international, multicenter, prospective clinical study for pediatric Langerhans Cell Histiocytosis LCH (age < 18 years).
Gender:
All
Ages:
18 years and below
Trial Updated:
03/21/2023
Locations: The Toledo Hospital, Toledo Children's Hospital, Toledo, Ohio
Conditions: Langerhans Cell Histiocytosis
Register for Updates
A Study to Evaluate EDP-235 in Non-hospitalized Adults With COVID-19
NCT05616728
Recruiting
Study of EDP-235 in Non-hospitalized Adults with Mild or Moderate COVID-19.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
12/06/2022
Locations: Toledo Institute of Clinical Research, Toledo, Ohio
Conditions: COVID-19
Register for Updates
Outcomes of Sclerotherapy of the Ulcer Bed Compared to a Combination of Ablation and Injections
NCT05633277
Recruiting
Randomized Controlled Trial to determine if the outcomes of sclerotherapy of the ulcer bed alone differ from a combination of ablation and sclerotherapy injections.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2022
Locations: Jobst Vascular Institute, ProMedica Toledo Hospital, Toledo, Ohio
Conditions: Venous Reflux, Venous Insufficiency, Venous Ulcer, Venous Disease
Register for Updates
Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty
NCT05307510
Recruiting
This study aims to compare post-surgical outcomes of individuals who receive either a custom orthosis or prefabricated splint after carpometacarpal arthroplasty.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2022
Locations: University of Toledo Medical Center, Toledo, Ohio
Conditions: Thumb Osteoarthritis
Register for Updates
CERENOVUS Neurothrombectomy Devices Registry
NCT05591183
Recruiting
A post-market registry evaluating the EmboTrap® Revascularization Device and CERENOVUS Large Bore Catheter/ EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/19/2022
Locations: Mercy Health St Vincent Medical Center, Toledo, Ohio
Conditions: Cerebral Stroke
Register for Updates
Outcomes Mandate National Integration With Cannabis as Medicine
NCT03944447
Recruiting
This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.
Gender:
All
Ages:
7 years and above
Trial Updated:
05/29/2022
Locations: OMNI Medical Services, Toledo, Ohio +1 locations
Conditions: Chronic Pain, Chronic Pain Syndrome, Chronic Pain Due to Injury, Chronic Pain Due to Trauma, Fibromyalgia, Seizures, Hepatitis C, Cancer, Crohn Disease, HIV/AIDS, Multiple Sclerosis, Traumatic Brain Injury, Sickle Cell Disease, Post Traumatic Stress Disorder, Tourette Syndrome, Ulcerative Colitis, Glaucoma, Epilepsy, Inflammatory Bowel Diseases, Parkinson Disease, Amyotrophic Lateral Sclerosis, Chronic Traumatic Encephalopathy, Anxiety, Depression, Insomnia, Autism, Opioid-use Disorder, Bipolar Disorder, Covid19, SARS-CoV Infection, COVID-19, Corona Virus Infection, Coronavirus
Register for Updates
Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy
NCT04857359
Recruiting
This study is designed to evaluate the safety and efficacy of dipraglurant in PD patients with dyskinesia (randomized 1:1 to receive active or placebo) for 12 weeks (1 week at 150 mg per day and 11 weeks at 300 mg per day). The primary efficacy assessment will be based on the Unified Dyskinesia Rating Scale (UDysRS). Patients who complete the 12-week blinded treatment period may have the option to roll into an open-label safety extension study for an additional 12-month treatment period.
Gender:
All
Ages:
Between 30 years and 85 years
Trial Updated:
05/18/2022
Locations: University of Toledo, Gardner-McMaster Parkinson Center, Toledo, Ohio
Conditions: Parkinson Disease, Dyskinesia, Drug-Induced, Dyskinesias
Register for Updates
MultiStem® Administration for Stroke Treatment and Enhanced Recovery Study
NCT03545607
Recruiting
A Phase 3 study to examine the safety and effectiveness of the allogeneic, adult stem cell investigational product, MultiStem, in adults who have suffered an acute ischemic stroke in the previous 18-36 hours.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/08/2022
Locations: Athersys Investigational Site 130, Toledo, Ohio
Conditions: Ischemic Stroke
Register for Updates
An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
NCT02633683
Recruiting
The objectives of the trial are to evaluate the long-term efficacy and safety of HORIZANT (Gabapentin Enacarbil) 600 mg daily, for the treatment of RLS in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe primary RLS.
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
06/07/2021
Locations: Mercy Health - Children's Hospital Pulmonary & Sleep Center, Toledo, Ohio
Conditions: RLS
Register for Updates