There are currently 8 active clinical trials seeking participants for Emphysema research studies. The states with the highest number of trials for Emphysema participants are California, Pennsylvania, Florida and Texas.
Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema
NCT05897424
Recruiting
Phase 2 open label extension study to evaluate SAR447537 (INBRX-101) in adults with AATD emphysema
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/31/2025
Locations: University of Alabama at Birmingham- Site Number : 105, Birmingham, Alabama +40 locations
Conditions: Alpha 1-Antitrypsin Deficiency, Emphysema
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Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
NCT06891755
Recruiting
The objective of this study is to assess the safety and efficacy of Apreo BREATHE system when used to support native airways and release trapped air in the treatment of adult COPD patients with emphysema suffering from dyspnea due to hyperinflation despite optimal medical treatment. The Apreo BREATHE Airway Scaffold is a permanent implant designed to tent open native airways. The study will include up to 250 participants at up to 25 study centers located in the United States and Europe. Study su... Read More
Gender:
ALL
Ages:
Between 40 years and 84 years
Trial Updated:
07/29/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +8 locations
Conditions: COPD, Emphysema
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STRIVE Post-Market Registry Study
NCT04302272
Recruiting
This is a single-arm, prospective, multi-center, Registry study to evaluate the long-term safety and effectiveness of the Spiration Valve System (SVS) for the treatment of severe emphysema in a post-market setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2025
Locations: Dignity Health St. Joseph's Hospital and Medical Center, Phoenix, Arizona +11 locations
Conditions: Emphysema
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Doxycycline for Emphysema in People Living With HIV (The DEPTH Trial)
NCT05382208
Recruiting
The purpose of this study is to determine if doxycycline will reduce progression of emphysema in people living with HIV. The secondary objectives are to examine the effects of doxycycline on change in quantity of emphysema, six minute walk distance, patient reported outcomes, ratio of forced expiratory volume in 1 second and forced vital capacity. Secondary objectives will also describe the safety and tolerability of doxycycline and determine if doxycycline is associated with development of ant... Read More
Gender:
ALL
Ages:
30 years and above
Trial Updated:
06/13/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama +20 locations
Conditions: Emphysema, HIV
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Emphysema Research Registry and Biosample Repository
NCT00307281
Recruiting
The Comprehensive Lung Center (CLC) at the University of Pittsburgh Medical Center (UPMC Health System) provides patients with any type of breathing or lung disorder a full range of diagnostic and therapeutic services. The Emphysema/COPD Research Center (ECRC) is a specialty clinic, within this center, that attempts to advance the understanding of emphysema and to evaluate new therapies for patients with emphysema. The Emphysema Research Registry will enable pulmonary research physicians to: 1)... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/24/2024
Locations: University of Pittsburgh Emphysema/COPD Research Center, Pittsburgh, Pennsylvania
Conditions: Emphysema, Chronic Obstructive Pulmonary Disease, Chronic Bronchitis
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Biological Effects of Quercetin in COPD Phase II
NCT06003270
Recruiting
This study determines whether quercetin supplementation reduces the inflammation and oxidative stress markers in patients with chronic obstructive pulmonary disease. It is small study with 8 subjects receiving quercetin 1000 mg/day, 8 patients receiving 500 mg/day and 4 subjects receive placebo.
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
04/05/2024
Locations: Nathaniel Marchetti, Philadelphia, Pennsylvania
Conditions: Chronic Obstructive Pulmonary Disease, Emphysema, Chronic Bronchitis With Airway Obstruction
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Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap
NCT03263130
Recruiting
The purpose of this cross-sectional, observational study is to evaluate the site and mechanism(s) for expiratory airflow limitation in chronic, treated, current or former smokers (\>15 pack years) with COPD, Emphysema, and Asthma-COPD Overlap with mild to severe expiratory airflow limitation. Treatment may include short and long acting inhaled beta2agonists, short and long acting inhaled muscarinic receptor antagonists, inhaled and or oral corticosteroid, oral antibiotic, supplemental oxygen, an... Read More
Gender:
ALL
Ages:
30 years and above
Trial Updated:
10/25/2023
Locations: Arthur F Gelb MD, Lakewood, California +1 locations
Conditions: COPD, Emphysema, Asthma COPD Overlap, Emphysema
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COPD Patient-Powered Research Network
NCT02803242
Recruiting
The COPD Patient-Powered Research Network (COPD PPRN) is a patient research registry with the goal of enrolling 75,000 or more COPD patients and those at risk who are willing to share their heath information over several years and participate in research. The COPD PPRN has built an online platform to allow volunteers to enroll electronically, complete surveys, be contacted about studies they qualify for and become connected to COPD resources. The goal of the registry is to speed research to find... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/08/2022
Locations: COPD Foundation, Washington, District of Columbia
Conditions: Chronic Obstructive Pulmonary Disorder, Chronic Obstructive Lung Disease, Emphysema, Chronic Bronchitis
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