There are currently 1875 clinical trials in Philadelphia, Pennsylvania looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Pennsylvania, Children's Hospital of Philadelphia, Fox Chase Cancer Center and Thomas Jefferson University. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Rheumatoid Arthritis Shared Decision Making
NCT05530694
Recruiting
Shared decision making is the first overarching principle for the treat to target guidelines for rheumatoid arthritis (RA) and has been proposed as a potential mechanism to reduce health disparities, however there is little evidence to inform effective ways to implement this practice in the care of Veterans with RA. The purpose of this project is to evaluate the effectiveness of a multi-component shared decision making intervention on RA disease activity, adherence to RA medications and patient... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2024
Locations: Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, Philadelphia, Pennsylvania
Conditions: Rheumatoid Arthritis
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RSSearch Patient Registry-Long Term Study of Use of SRS/SBRT
NCT01885299
Recruiting
The RSSearch® Registry is an international multi-year database designed to track SRS/SBRT (Stereotactic Radiosurgery/Stereotactic Body Radiation Therapy) utilization, treatment practices and outcomes to help determine, over time, the most effective use of these systems in management of patients with life threatening tumors and other diseases. (This study was formally called ReCKord and included the CyberKnife only; The ReCKord study continues as a CyberKnife subset of RSSearch.)
Gender:
ALL
Ages:
All
Trial Updated:
09/17/2024
Locations: Philadelphia CyberKnife, Philadelphia, Pennsylvania
Conditions: Neoplasms, Arteriovenous Malformation of Central Nervous System, Trigeminal Neuralgia
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Reducing Empiric VAncomycin Use in Pediatric Suspected Sepsis
NCT05975671
Recruiting
The goal of this quasi-experimental interventional study is to determine the effectiveness of a multifaceted stewardship intervention in reducing overall vancomycin use in five tertiary care Pediatric Intensive Care Units (PICU). There are two groups of subjects in this study: PICU clinicians/sepsis stakeholders and patients admitted to one of the participating PICUs during the study period. The intervention will at a minimum include: * Implementation of a clinical guideline indicating when va... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/17/2024
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Sepsis, Sepsis Mrsa, Sepsis Bacteremia, Antimicrobial - Induced Nephropathy, Sepsis, Severe, Septic Shock, Septic Syndrome
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First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors
NCT06554795
Recruiting
A Phase 1/2a First-in-Human Study of DB-1419 in Advanced/Metastatic Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/17/2024
Locations: Site USA05-0, Philadelphia, Pennsylvania
Conditions: Solid Tumor, Adult
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Study of SGR-2921 in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome
NCT05961839
Recruiting
The purpose of this study is to evaluate safety and tolerability and to determine the maximum tolerated dose (MTD) and/or recommended dose (RD) of SGR-2921.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/13/2024
Locations: Thomas Jefferson University, Sidney Kimmel Cancer Center, Clinical Research Organization, Philadelphia, Pennsylvania
Conditions: Acute Myeloid Leukemia, High-Risk and Very High-Risk Myelodysplastic Syndromes
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AMBU Bag Manual Ventilation Vs. Transport Ventilator Mechanical Ventilation for Transport
NCT06006208
Recruiting
This is a clinical trial to compare the oxygenation and ventilation performance between manual ventilation and mechanical ventilation when transporting cardiac patients to the ICU.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2024
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Oxygenation, Manual Ventilation, Mechanical Ventilation, Point of Care Ultrasound, Cardiac Function Disturbance Postoperative
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Postpartum Care in the NICU (PeliCaN) Transitions
NCT06521398
Recruiting
This is a randomized controlled trial of a dyad-centered, doula support and healthcare coordination model of care in a large urban neonatal intensive care unit (NICU), which serves a high-risk, low-income, majority Black population. In addition to doula support and coordination of care in the NICU, there will be a warm handoff to a community doula to continue the support once infants leave the Hospital of the University of Pennsylvania (HUP) NICU.
Gender:
FEMALE
Ages:
16 years and above
Trial Updated:
09/11/2024
Locations: Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Stress Disorders, Post-Traumatic, Premature Birth, Postpartum Depression, Postpartum Anxiety
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International CDKL5 Registry
NCT04486768
Recruiting
Owing to the recent classification of CDKL5 Deficiency Disorder (CDD) as a unique disorder, there is a limited understanding of overall disease natural history and meaningful outcome measures. An international patient registry aimed at collecting both patient/caregiver and clinician-entered demographic, patient-reported outcome (PRO) and treatment data would benefit both the scientific and patient communities. This CDD registry will follow up to 500 patients diagnosed with CDD over several years... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/10/2024
Locations: University of Pennsylvania Orphan Disease Center, Philadelphia, Pennsylvania
Conditions: CDKL5 Deficiency Disorder (CDD)
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Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial Hypertension
NCT06543745
Recruiting
The purpose of the study is to learn more about how low-resistance training impacts frailty and the quality of life of people with pulmonary arterial hypertension (PAH). Low-resistance training is an evidence-based approach that may help patients improve their functional ability.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: University of Pennsyvania, Philadelphia, Pennsylvania
Conditions: Pulmonary Arterial Hypertension, Frailty
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Pilot Trial of the RUBI Program for Autistic Adults
NCT06593613
Recruiting
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors. The main questions it aims to answer are: * Is the redesigned RUBI intervention feasible and acceptable for autistic adults and their families? * Does the redesigned RUBI intervention reduce challenging behaviors and enhance the quality of life for autistic adults? * Rese... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2024
Locations: A.J. Drexel Autism Institute, Philadelphia, Pennsylvania
Conditions: Autism Spectrum Disorder, Behavior, Parenting
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Cigarette Packaging of Low Nicotine Cigarettes
NCT03802019
Recruiting
The purpose of this study is to examine the effect of changes in cigarette package color on smoking behaviors, harm exposure, and risk perceptions when using low nicotine content (LNC) cigarettes.
Gender:
ALL
Ages:
Between 21 years and 65 years
Trial Updated:
09/05/2024
Locations: Center for Interdisciplinary Research for Nicotine Addiction, Philadelphia, Pennsylvania
Conditions: Smoking, Cigarette
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A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease
NCT05733832
Recruiting
Patients with complications of advanced liver disease often have difficulties after hospital discharge that result in early hospital readmission. Poor outcomes for these patients during this transitional time could be improved through the use of innovative transitional care models. This proposal aims to examine the effect of a transitional care model, The Transitional Liver Clinic (TLC), in reducing hospital re-admissions, improving quality of life, and improving patient experience.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/05/2024
Locations: Albert Einstein Healthcare Network, Philadelphia, Pennsylvania
Conditions: Liver Diseases
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