The city of Pittsburgh, Pennsylvania, currently has 13 active clinical trials seeking participants for Depression research studies.
Rapid Antidepressant Improvement Secondary to Excitatory Brain Responses
Recruiting
The central goal of this application is to demonstrate the causal contribution of reward learning signals (expected values and reward prediction errors \[RPE\]) to antidepressant responses (Aim1) by experimentally manipulating expected values using transcranial magnetic stimulation (TMS) targeting the vmPFC (Aim 2) and μ-opioid striatal RPE signal using pharmacological approaches (Aim 3).
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/01/2024
Locations: Bellefield Tower, Pittsburgh, Pennsylvania
Conditions: Major Depressive Disorder, Depression