The state of South Carolina currently has 15 active clinical trials seeking participants for Arthritis research studies. These trials are conducted in various cities, including Charleston, Greenville, Spartanburg and Columbia.
A Study of Retatrutide (LY3437943) in Participants Who Have Obesity or Overweight
Recruiting
The purpose of this study is to evaluate the efficacy and safety of retatrutide in participants who have obesity or overweight (J1I-MC-GZBJ master protocol) including subsets of participants who have knee osteoarthritis (OA) (J1I-MC-GOA1) or who have obstructive sleep apnea (OSA) (J1I-MC-GSA1). This study will last about 89 weeks and will include up to 24 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/17/2024
Locations: Tribe Clinical Research, LLC, Greenville, South Carolina +1 locations
Conditions: Obesity, Overweight, Knee Pain Chronic, Knee Osteoarthritis, Obstructive Sleep Apnea
Long Term Evaluation of Safety and Efficacy of Tildrakizumab in Patients With Psoriatic Arthritis
Recruiting
An open label phase 3 study
Gender:
All
Ages:
18 years and above
Trial Updated:
06/10/2024
Locations: Sunpharma site no 31, Greenville, South Carolina
Conditions: Psoriatic Arthritis
Phase 3 Evaluation of Efficacy and Safety of AR882 in Gout Patients
Recruiting
This study will assess the serum uric acid lowering effect and safety of AR882 in gout patients at two doses compared to placebo over 12 months
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/31/2024
Locations: Arthrosi Investigative Site (147), Myrtle Beach, South Carolina
Conditions: Gout, Arthritis, Gouty, Hyperuricemia, Gout Chronic
Efficacy and Safety of Tildrakizumab Compared to Placebo in Subjects With Active Psoriatic Arthritis I (INSPIRE 1)
Recruiting
This is a multicenter Phase III, Randomized, Double-Blind, Single-Dose, Placebo-Controlled Study to Demonstrate the Efficacy and Safety of tildrakizumab in Subjects with Active Psoriatic Arthritis I (INSPIRE 1)
Gender:
All
Ages:
18 years and above
Trial Updated:
05/28/2024
Locations: Sunpharma Site no 34, Greenville, South Carolina
Conditions: Active Psoriatic Arthritis
A Study of Baricitinib in Participants With Rheumatoid Arthritis
Recruiting
This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/27/2024
Locations: Articularis Healthcare d/b/a/ Low Country Rheumatology, PA, Summerville, South Carolina
Conditions: Rheumatoid Arthritis
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: Coastal Carolina Research Center, North Charleston, South Carolina
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
Recruiting
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis. Participants will receive an injection of MFat or saline.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2024
Locations: Coastal Carolina Research Center, North Charleston, South Carolina
Conditions: Knee Osteoarthritis, Osteo Arthritis Knee
Study of Dapansutrile Tablets in Subjects With an Acute Gout Flare
Recruiting
The purpose of this trial is to investigate the efficacy and safety of dapansutrile (OLT1177®) tablets in subjects with an acute gout flare.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/01/2024
Locations: Lower Country Rheumatology - Summerville, Summerville, South Carolina
Conditions: Acute Gout Flare, Gout Attack, Gout Flare, Gouty Arthritis, Gout, Arthritis, Joint Pain
Post Approval Study2: Hintermann Series H3 Total Ankle Replacement System
Recruiting
The H3 TAR Prosthesis was approved by FDA (P160036) on June 4, 2019. Continued approval of the premarket approval application (PMA) is contingent upon the submission of periodic reports (Annual Report), required under 21 CFR 814.84. In order to provide continued reasonable assurance of the safety and effectiveness of the PMA device, data from this post-approval study must be submitted to FDA in a PMA Post-Approval Study Report per the requirements set forth in the approval.
Gender:
All
Ages:
21 years and above
Trial Updated:
03/07/2024
Locations: MUSC Department of Orthopaedics/Foot and Anke Services, Charleston, South Carolina
Conditions: Osteoarthritis Ankle, Post-Traumatic Osteoarthritis of Ankle, Osteoarthritis of Ankle Secondary to Inflammatory Arthritis (Disorder)
Bayer OA Knee Pain Pilot
Recruiting
The objective of this study is to investigate if MRI can be used to evaluated effect of knee artery embolization for knee osteoarthritis. Participants be evaluated in clinic, obtain a knee MRI, undergo embolization of the symptomatic knee, and follow up in clinic at 1, 6, and 12 months after embolization. A second MRI is obtained 6 months after embolization. Participants will keep a record of their pain level and treatment and answer questionnaires at each visit. In addition, this study aims to... Read More
Gender:
All
Ages:
Between 25 years and 90 years
Trial Updated:
03/01/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Osteoarthritis, Knee
Exactech Shoulder Post Market Clinical Follow-up Study
Recruiting
The objective of this study is to collect and evaluate long-term clinical and radiographic outcomes data in order to better understand the safety and performance of the shoulder arthroplasty over time. This study will follow subjects long-term for a minimum of 10-years, without an early-term restriction on the amount of time they will be followed.
Gender:
All
Ages:
21 years and above
Trial Updated:
02/23/2024
Locations: Charleston Orthopaedic Associates, Charleston, South Carolina +1 locations
Conditions: Osteo Arthritis Shoulders, Osteonecrosis, Rotator Cuff Tears, Rotator Cuff Tear Arthropathy, Ankylosing Spondylitis, Post-traumatic Osteoarthritis, Rheumatoid Arthritis, Fracture, Infections
INFINITY™ With ADAPTIS™ Technology Study
Recruiting
INFINITY™ with ADAPTIS™ Technology Total Ankle Replacement Follow-up (ITAR2) - Prospective, multi-site, multi-year post-market clinical follow-up study Study Group Primary/Unilateral and/or bilateral Total Ankle Arthroplasty subjects implanted with INFINITY™ Total Ankle System Number of Subjects 200 patients with up to 13 sites
Gender:
All
Ages:
22 years and above
Trial Updated:
02/16/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Arthritis, Rheumatoid