The state of South Carolina currently has 6 active clinical trials seeking participants for Narcolepsy research studies. These trials are conducted in various cities, including Charleston, Greenville, Spartanburg and Columbia.
A Study of TAK-861 for the Treatment of Narcolepsy Type 1
Recruiting
The main aim of this study is to learn how effective TAK-861 is in improving excessive sleepiness during the day (called excessive daytime sleepiness or EDS) after 3 months of treatment. Other aims are to learn how effective TAK-861 is in lowering the number of sudden, unexpected attacks of muscle weakness while staying conscious (cataplexy) in a week; to learn the effect TAK-861 has on participants' ability to maintain attention, participant's overall quality of life, the spectrum of narcolepsy... Read More
Gender:
ALL
Ages:
Between 16 years and 70 years
Trial Updated:
02/13/2025
Locations: Takeda Site 1, Columbia, South Carolina
Conditions: Narcolepsy Type 1
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects with Narcolepsy Type 1 (ALKS 2680-201)
Recruiting
The purpose of this research study is to assess the safety and efficacy of ALKS 2680 compared to placebo, including whether participants taking ALKS 2680 experience a greater decrease in sleepiness and a decrease in cataplexy ("sudden loss of muscle control"), compared to participants taking placebo alone.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/05/2025
Locations: Alkermes Investigational Site, Columbia, South Carolina
Conditions: Narcolepsy Type 1
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects with Narcolepsy Type 2
Recruiting
The purpose of this study is to measure the safety and decrease in sleepiness in subjects with narcolepsy type 2 (NT2) when taking ALKS 2680 tablets compared to placebo tablets.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/05/2025
Locations: Alkermes Investigator Site, Columbia, South Carolina
Conditions: Narcolepsy Type 2
Observational Study of LUMRYZ in Narcolepsy
Recruiting
This is an observational study of LUMRYZ prescribed in clinical practice. Patients are asked if they would be willing to complete questionnaires over a 4-month period after starting LUMRYZ. The questionnaires ask about narcolepsy symptoms, experience with LUMRYZ, and quality of life.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: Bogan Sleep Consultants, Columbia, South Carolina
Conditions: Narcolepsy
A Study of ORX750 in Participants with Narcolepsy and Idiopathic Hypersomnia
Recruiting
The purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) of ORX750.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/23/2024
Locations: Centessa Investigational Site, Columbia, South Carolina
Conditions: Narcolepsy Type 1, Narcolepsy Type 2, Idiopathic Hypersomnia
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 narcolepsy, who were exposed to previously tested doses of TAK-861.
Gender:
ALL
Ages:
Between 16 years and 70 years
Trial Updated:
09/24/2024
Locations: Medical University of South Carolina - PPDS, Charleston, South Carolina +1 locations
Conditions: Narcolepsy Type 1