The state of South Carolina currently has 5 active clinical trials seeking participants for Narcolepsy research studies. These trials are conducted in various cities, including Charleston, Greenville, Spartanburg and Columbia.
Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)
Recruiting
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-6552 in participants with Narcolepsy Type 1 (NT1). Part 1 will evaluate safety, tolerability, and PK of MK-6552 after administration of ascending doses in a single day to support a dose level decision for Part 2. Part 2 will investigate the PD of MK-6552 after single-day and multiple-day administration. Participants who complete Part 1 and demonstrate that they are able to tolera... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/20/2024
Locations: Bogan Sleep Consultants ( Site 0001), Columbia, South Carolina
Conditions: Narcolepsy
A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina +2 locations
Conditions: Narcolepsy
A Study to Evaluate the Safety and Effectiveness of ALKS 2680 in Subjects With Narcolepsy Type 1 (ALKS 2680-201)
Recruiting
The purpose of this research study is to assess the safety and efficacy of ALKS 2680 compared to placebo, including whether participants taking ALKS 2680 experience a greater decrease in sleepiness and a decrease in cataplexy ("sudden loss of muscle control"), compared to participants taking placebo alone.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
05/07/2024
Locations: Alkermes Investigational Site, Columbia, South Carolina
Conditions: Narcolepsy Type 1
Ph4 PSG Combined JZP258-407
Recruiting
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/29/2024
Locations: Bogan Sleep Consultants, LLC, Columbia, South Carolina
Conditions: Idiopathic Hypersomnia, Narcolepsy
A Study of TAK-861 for the Treatment of Selected Central Hypersomnia Conditions
Recruiting
The main aim is to evaluate the safety and tolerability of TAK-861 on participants with type 1 and type 2 narcolepsy from previous parent studies, TAK-861-2001 (NCT05687903) and TAK-861-2002 (NCT05687916).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
02/15/2024
Locations: Medical University of South Carolina - PPDS, Charleston, South Carolina +1 locations
Conditions: Narcolepsy Type 1, Narcolepsy Type 2