There are currently 3 active clinical trials seeking participants for Cocaine Dependence research studies. The states with the highest number of trials for Cocaine Dependence participants are Texas, Connecticut, Pennsylvania and New York.
Safety Study of a Disrupted Adenovirus (Ad) Serotype Cocaine Vaccine for Cocaine-dependent Individuals
NCT02455479
Recruiting
The purpose of this study is to assess the safety and preliminary efficacy of an anti-cocaine vaccine called dAd5GNE in cocaine-dependent individuals. It uses the concept of a vaccine to treat the neurological effects of cocaine by evoking "immunity" to prevent the effects of cocaine on the brain.
Gender:
ALL
Ages:
Between 21 years and 69 years
Trial Updated:
11/15/2024
Locations: WCMC Department of Genetic Medicine, New York, New York
Conditions: Cocaine Dependence
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Substance Abuse Pre-Treatment Screening Study
NCT00439049
Recruiting
The overarching goal of this project is to have a consolidated consent and evaluation procedure that will lead potential subjects to the most appropriate clinical trial or human laboratory study (and its consent process) for their presenting concerns or interests. A second purpose is to have a consolidated intake data base on which secondary analyses can be conducted.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
12/19/2023
Locations: University of Texas Medical School- Houston, Dept. of Psychiatry Mental Sciences Institute, Houston, Texas
Conditions: Cocaine Abuse, Cocaine Dependence, Opiate Dependence, Alcohol Dependence, Substance Abuse
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Low-Intensity Focused Ultrasound for Cocaine Use Disorder
NCT05857852
Recruiting
This study aims to understand the role of Low-Intensity Focused Ultrasound on craving levels for cocaine as evidenced by diagnostic imaging of the dorsal anterior insula (dAI) and subjective ratings. Data analysis will serve to show if 1) LIFU is safe and effective and to 2) examine the effects of LIFU on dAI BOLD activity and craving in response to cocaine cue-exposure. The study will screen 60 individuals with Cocaine Use Disorder (CUD) to arrive at 30 enrolled subjects, based on a 2:1 screen/... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/04/2023
Locations: UVA Center for Leading Edge Addiction Research, Charlottesville, Virginia
Conditions: Cocaine Use Disorder, Cocaine Dependence, Cocaine Abuse, Ultrasound
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