The state of Texas currently has 82 active clinical trials seeking participants for Pain research studies. These trials are conducted in various cities, including Houston, Dallas, San Antonio and Austin.
Study Assessing Pain Relief After Replacement of the Knee
Recruiting
The goal of the ATX101-TKA-004 clinical trial aims to evaluate the efficacy and safety of ATX101 1,500 mg in participants undergoing primary unilateral total knee arthroplasty. The study will compare the effectiveness of ATX101 with a saline placebo and bupivacaine, an active comparator. Additionally, it will assess opioid consumption among participants receiving ATX101 versus those given the saline placebo and bupivacaine. The trial will also focus on the safety and tolerability of ATX101 in th... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/24/2025
Locations: First Surgical Hospital, Bellaire, Texas +4 locations
Conditions: Total Knee Arthroplasty (postoperative Pain)
Anesthetics and Analgesics in Children
Recruiting
The purpose of this study is to characterize the pharmacokinetic (PK) and safety profile of anesthetics and analgesics in children and adolescents.
Gender:
ALL
Ages:
Between 0 years and 17 years
Trial Updated:
01/21/2025
Locations: Dell Children's Medical Center of Texas, Austin, Texas +1 locations
Conditions: Anesthesia, Pain
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
Recruiting
The purpose of the chronic pain master protocol is to compare independent pain interventions and establish an overarching structure for the disease-state addenda (DSA) and intervention-specific appendices (ISAs). The ISAs may start independently of other ISAs as interventions become available for clinical testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: FutureSearch Trials of Neurology, Austin, Texas +3 locations
Conditions: Osteoarthritis, Knee, Diabetic Neuropathic Pain, Chronic Low-back Pain
Effects of LY3848575 Versus Placebo in Participants With Painful Distal Sensory Polyneuropathy
Recruiting
The purpose of this study is to evaluate how safe and how well a treatment works compared to placebo for people with nerve pain that begins in their feet and moves up the leg to just below the knee. Participation may last up to 30 weeks including screening.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/20/2025
Locations: Cedar Health Research, Dallas, Texas +2 locations
Conditions: Neuropathic Pain, Distal Sensory Polyneuropathy
Patient Retrospective Outcomes (PRO)
Recruiting
This study will evaluate de-identified (anonymous) data in subject medical charts to review the clinical outcomes of various treatment approaches in the treatment of chronic pain.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/15/2025
Locations: Pain Center Physicians, Austin, Texas +6 locations
Conditions: Chronic Pain
A Study Evaluating Efficacy and Safety of VX-993 for Acute Pain After a Bunionectomy
Recruiting
The purpose of this study is to evaluate the efficacy, safety, tolerability and pharmacokinetics of VX-993 in treating acute pain after a bunionectomy.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/14/2025
Locations: BioBehavioral Research of Austin, Austin, Texas +4 locations
Conditions: Acute Pain
Non-pharmacological Treatment for Pain After Spine Surgery
Recruiting
This study will compare the effectiveness of two pain management pathways (standard vs. enriched) for patients undergoing lumbar spine surgery in the Military Health System (MHS). Effectiveness will be based on post-surgery patient-centered outcomes and extent of opioid use. The study design is a 2-arm, parallel group, individual-randomized trial.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
01/13/2025
Locations: Brooke Army Medical Center, San Antonio, Texas
Conditions: Low Back Pain, Chronic Pain, Surgery, Back Pain, Low, Back Pain Lower Back Chronic
Auricular Acupuncture As Part Of A Multimodal Regimen After Distal Radius Open Reduction and Internal Fixation
Recruiting
This randomized controlled trial will test the hypothesis that patients receiving an intraoperative auricular acupuncture protocol will require less postoperative opioid analgesic use compared to those who do not receive acupuncture in the setting of a multimodal analgesic protocol for patients receiving surgery to repair distal radius fractures at a Level 1 trauma center under brachial plexus anesthesia with sedation.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Radius Fracture Distal, Pain, Postoperative
Acupuncture for Prevention of Postoperative Nausea and Vomiting After Laparoscopic Cholecystectomy
Recruiting
The purpose is to find out if intraoperative acupuncture performed by needling PC 6 and LI4 point bilaterally, and Yin Tang point will help reduce the incidence postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy when added to a prophylactic regimen consisting of ondansetron and dexamethasone. The hypothesis is that the addition of this acupuncture treatment to ondansetron and dexamethasone given for prophylaxis will help reduce the incidence of postoperative na... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Cholecystitis, Acute, Cholelithiasis, Nausea, Postoperative, Vomiting, Postoperative, Pain, Postoperative
Auricular Acupuncture as Part of Multimodal Analgesia After Lower Leg Fracture
Recruiting
The purpose is to find out if incorporation of an intraoperative electro auricular acupuncture protocol when added to a standard multimodal analgesic regimen for patients undergoing surgery to repair lower leg fracture under spinal anesthesia will help reduce postoperative opioid use.
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/13/2025
Locations: Ben Taub Hospital, Houston, Texas
Conditions: Pain, Postoperative, Fracture, Ankle, Pilon Fracture of Tibia, Foot Fracture
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
Recruiting
The purpose of this study is to evaluate the efficacy, safety, and tolerability of VX-993 in participants with pain associated with Diabetic Peripheral Neuropathy (DPN)
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/10/2025
Locations: Velocity Clinical Research, Dallas, Dallas, Texas +1 locations
Conditions: Diabetic Peripheral Neuropathic Pain
RELIEF - A Global Registry to Evaluate Long-Term Effectiveness of Neurostimulation Therapy for Pain
Recruiting
To compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use - and - To evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/10/2025
Locations: Balcones Pain Consultants, Austin, Texas +3 locations
Conditions: Pain