There are currently 151 clinical trials in Plano, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including The Heart Hospital Baylor Plano, Texas Oncology - Plano East, GSK Investigational Site and Texas Back Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
PATHFINDER 2: A Multi-Cancer Early Detection Study
Recruiting
This is a prospective, multi-center interventional study of the GRAIL multi-cancer early detection (MCED) test with return of test results for participants enrolled through healthcare systems in North America. The purpose of this study is to evaluate the safety and performance of the GRAIL MCED test in a population of individuals who are eligible for guideline-recommended cancer screening. In cases with a "cancer signal detected" test result, participants will undergo diagnostic procedures based... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
03/01/2024
Locations: Texas Oncology - Plano East, Plano, Texas +1 locations
Conditions: Early Detection of Cancer, Cancer
Cardiovascular Outcome Study to Evaluate the Effect of Obicetrapib in Patients With Cardiovascular Disease
Recruiting
This study will be a placebo-controlled, double-blind, randomized, phase 3 study in participants with Atherosclerotic Cardiovascular Disease (ASCVD) who are not adequately controlled despite maximally tolerated lipid-lowering therapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/01/2024
Locations: Styde Research, Plano, Texas
Conditions: Atherosclerotic Cardiovascular Disease
Phase 2b Pivotal Study of Izokibep in Non-infectious, Intermediate-, Posterior- or Pan-uveitis
Recruiting
Izokibep is a small protein molecule that acts as a selective, potent inhibitor of interleukin-17A, to which it binds with high affinity. This study investigates izokibep in subjects with active non-infectious, intermediate-, posterior- or pan-uveitis requiring high-dose steroids.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
02/29/2024
Locations: Clinical Research Site, Plano, Texas
Conditions: Uveitis
A Study of Imlunestrant Versus Standard Endocrine Therapy in Participants With Early Breast Cancer
Recruiting
The main purpose of this study is to measure how well imlunestrant works compared to standard hormone therapy in participants with early breast cancer that is estrogen receptor positive (ER+) and human epidermal receptor 2 negative (HER2-). Participants must have already taken endocrine therapy for two to five years and must have a higher-than-average risk for their cancer to return. Study participation could last up to 10 years.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: USO - Texas Oncology, Plano, Texas
Conditions: Breast Neoplasms
POC Study to Evaluate the Efficacy and Safety of ESK-001 in Patients With Active Intermediate, Posterior, or Pan NIU
Recruiting
This is a multi-center, randomized, double-masked, proof-of-concept study in patients with Active Noninfectious Intermediate, Posterior, or Panuveitis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
02/29/2024
Locations: Investigator Site #1078, Plano, Texas
Conditions: Uveitis Posterior Non-Infectious, Uveitis, Intermediate, Noninfectious Panuveitis
Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder
Recruiting
The purpose of this study is to evaluate the safety and efficacy of individualized, Biometrics-guided Magnetic e-Resonance Therapy (MeRT) treatment of Post-Traumatic Stress Disorder
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/29/2024
Locations: Texas A&M Research Center, Plano, Texas
Conditions: Postconcussive Symptoms, Traumatic Brain Injury, PostTraumatic Stress Disorder
A Study of Baricitinib in Participants With Rheumatoid Arthritis
Recruiting
This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: Clinrx Research Joseph INC., Plano, Texas
Conditions: Rheumatoid Arthritis
A Prospective Registry Study to Assess Real-world Patient Characteristics, Treatment Patterns, and Longitudinal Outcomes in Patients Receiving Mavacamten and Other Treatments for Symptomatic Obstructive Hypertrophic Cardiomyopathy (Obstructive HCM)
Recruiting
The purpose of this study is to evaluate the safety of mavacamten in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM) treated in the real-world setting. The registry study also provide a real-world understanding of the current obstructive HCM patient population, treatment patterns, and clinical relevant outcomes for patients with symptomatic obstructive HCM in the US.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Baylor Scott & White The Heart Hospital Plano, Plano, Texas
Conditions: Obstructive Hypertrophic Cardiomyopathy
Efficacy and Safety Study of Adjunctive Troriluzule in Obsessive Compulsive Disorder
Recruiting
The study's purpose its to evaluate the efficacy and safety of troriluzole as adjunctive therapy compared to placebo in subjects with Obsessive Compulsive Disorder (OCD)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/23/2024
Locations: AIM Trials, Plano, Texas
Conditions: Obsessive-Compulsive Disorder
Study of Cariprazine Oral Capsules or Solution to Assess Adverse Events and Change in Irritability Due to Autism Spectrum Disorder (ASD) in Participants Aged 5-17 Years With ASD
Recruiting
Autism spectrum disorder (ASD) consists of deficits in social, communication, and cognitive development, repetitive and stereotypic behaviors. Many ASD patients show notably high levels of irritability, including verbal and physical aggression, self injury, and/or property destruction. Autistic infants tend to avoid eye contact and show little interest in others. This study will assess how safe and effective cariprazine is in treating pediatric participants (5 to 17 years of age) with ASD. Adver... Read More
Gender:
All
Ages:
Between 5 years and 17 years
Trial Updated:
02/23/2024
Locations: AIM Trials /ID# 243120, Plano, Texas
Conditions: Autism Spectrum Disorder
A Study of Mavacamten in Non-Obstructive Hypertrophic Cardiomyopathy
Recruiting
The purpose of this study is to evaluate the safety, tolerability, and efficacy of mavacamten compared with placebo in participants with symptomatic non-obstructive hypertrophic cardiomyopathy (nHCM).
Gender:
All
Ages:
18 years and above
Trial Updated:
02/23/2024
Locations: Baylor Scott & White Hospital - Plano, Plano, Texas
Conditions: Cardiomyopathy, Hypertrophic
Linaclotide Safety and Efficacy in Pediatric Participants, 6 to 17 Years of Age, With Irritable Bowel Syndrome With Constipation (IBS-C) or Functional Constipation (FC)
Recruiting
The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (72 μg daily) in comparison with placebo in pediatric participants, 6 to 17 years of age, who fulfill modified Rome III Criteria for Child/Adolescent Functional Constipation (FC). The objective of LIN-MD-64 is to evaluate the safety and efficacy of 12 weeks of linaclotide therapy (145 μg or 290 μg daily) in pediatric participants, 7 to 17 years of age, who fulfill the Rome III criteria for child/... Read More
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
02/22/2024
Locations: AIM Trials /ID# 232934, Plano, Texas
Conditions: Functional Constipation, Irritable Bowel Syndrome With Constipation