There are currently 164 clinical trials in Plano, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including The Heart Hospital Baylor Plano, Texas Oncology - Plano East, GSK Investigational Site and Texas Back Institute. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: AIM Trials, LLC, Plano, Texas
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
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A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Rheumatoid Arthritis (RENOIR)
NCT06041269
Recruiting
RENOIR Study: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe Rheumatoid Arthritis (RA)
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/11/2023
Locations: Anaptys Bio Investigative Site 10-110, Plano, Texas
Conditions: Rheumatoid Arthritis
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A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)
NCT04636801
Recruiting
The purpose of the study is to evaluate the efficacy and safety of two doses of CHF6001 (Tanimilast), as add-on to maintenance triple therapy in the target patient population.
Gender:
All
Ages:
40 years and above
Trial Updated:
10/02/2023
Locations: Chiesi Clinical Trial - Site 840409, Plano, Texas
Conditions: Chronic Obstructive Pulmonary Disease
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Abt, Concussion Screen Use Recovery Time
NCT05373992
Recruiting
A two-year parallel randomized clinical trial study to examine the effect of screen time (ST) restriction, exercise alone, and combined ST-restricted-exercise when compared to stretching only (control group) on sports related concussion recovery time among adolescents aged 12 to 17 years. Study hypothesis 1 - There will be significant differences between the treatment and the control arms' mean recovery time (days). Study hypothesis 2 - The ST-restricted & exercise treatment arm will have a sign... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
09/25/2023
Locations: Children's Health - Andrews Institute, Plano, Texas
Conditions: Sport-related Concussion
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AltaValve Early Feasibility Study Protocol
NCT03997305
Recruiting
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: Baylor Scott & White, Plano, Texas
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
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A Follow-up Study to Describe the Safety of Study Participants Who Received RSVPreF3 Maternal Vaccination (Any Dose) or Controls From Previous RSV MAT Studies During Any Pregnancy Conceived Post Vaccination/Control
NCT05705440
Recruiting
The purpose of this follow-up study is to describe the safety in subsequent pregnancies in participants who were previously administered the RSVPreF3 maternal vaccine or control during any prior RSV MAT study. The study participants enrolled in this follow-up study received RSVPreF3 maternal vaccination (any dose) or controls during the following prior RSV MAT studies: RSV MAT-001 (NCT03674177), RSV MAT-004 (NCT04126213), RSV MAT-010 (NCT05045144), RSV MAT-011 (NCT04138056), RSV MAT-009 (NCT046... Read More
Gender:
Female
Ages:
Between 9 years and 49 years
Trial Updated:
08/30/2023
Locations: GSK Investigational Site, Plano, Texas
Conditions: Respiratory Syncytial Virus Infections
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A Prospective and Retrospective Observational Study of Multidrug-Resistant Patient Outcomes With and Without Ibalizumab
NCT05388474
Recruiting
The virological efficacy of ibalizumab has been clearly demonstrated in multiple clinical trials. This study will expand ibalizumab's clinical data set and allow a better understanding of the virologic response durability on ARV regimens with or without ibalizumab in a heterogeneous real-world patient population. Additional data on the efficacy and safety of ibalizumab and its impact on patient reported outcomes will be captured until study end. Primary Objective: To evaluate the long-term eff... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/20/2023
Locations: North Texas Infectious Diseases Consultants, P.A., Plano, Texas
Conditions: HIV Infections, Multi-Antiviral Resistance
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Intravascular Lithotripsy in High Risk Calcified Iliac Anatomy for Transfemoral TAVR
NCT05862558
Recruiting
To assess the efficacy and safety of Intravascular Lithotripsy (IVL) in subjects undergoing transfemoral TAVR in patients with severe iliac disease, prohibitive for transfemoral TAVR in patients with severe symptomatic aortic stenosis, otherwise considered for alternative access TAVR. (e.g. trans-carotid)
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
05/08/2023
Locations: Baylor Scott and White Heart Hospital, Plano, Texas
Conditions: Iliac Disease, Aortic Valve Stenosis
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Evaluation of Performance of the LumiraDx Influenza A/B + RSV Test at POC Testing Sites
NCT04288921
Recruiting
A Multicenter Study Conducted to Evaluate the Performance of the LumiraDx Influenza A/B + RSV Test at Point of Care Testing Sites
Gender:
All
Ages:
All
Trial Updated:
03/10/2023
Locations: North Texas Family Practice, Plano, Texas
Conditions: Influenza, Human, Respiratory Syncytial Virus Infections
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AngioSafe Peripheral CTO Crossing System Study (RESTOR-1 Study)
NCT04663867
Recruiting
The study is designed to evaluate the safety and efficacy of the AngioSafe Peripheral CTO Crossing System.
Gender:
All
Ages:
22 years and above
Trial Updated:
11/22/2022
Locations: Baylor Scott & White, The Heart Hospital Plano, Plano, Texas
Conditions: Peripheral Artery Occlusion, Peripheral Arterial Disease
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Prospective Evaluation of Neurocognition in Patients Undergoing Transcatheter Aortic Valve Replacement
NCT05614986
Recruiting
This trail is for patients with mild cognitive impairment (MCI) who are receiving a transcatheter aortic valve replacement (TAVR). We will assess changes in neurocognition following TAVR with the 5 minute Montreal Cognitive Assessment (mini MoCA) when comparing pre procedure with post procedure assessments.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/07/2022
Locations: Baylor Scott and White The Heart Hospital Baylor Plano, Plano, Texas
Conditions: Mild Cognitive Impairment, Aortic Stenosis
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The Use of Two YUTIQ Versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment
NCT05486468
Recruiting
The Use of Two YUTIQ versus Sham for Treatment of Chronic Non Infectious Intraocular Inflammation Affecting the Posterior Segment (TYNI Trial)
Gender:
All
Ages:
18 years and above
Trial Updated:
10/27/2022
Locations: Texas Retina Associates, Plano, Texas
Conditions: Uveitis, Uveitis, Posterior, Uveitis, Anterior, Uveitis, Intermediate
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