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Dexamethasone Treatment Options
A collection of 1461 research studies where Dexamethasone is the interventional treatment. These studies are located in the United States . Dexamethasone is used for conditions such as Multiple Myeloma, Postoperative Pain and Lymphoma.
577 - 588 of 1461
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Post Operative Pain Management for ACL Reconstruction
Enrolling By Invitation
Health care providers are seeking methods to limit post-operative pain and opioid prescriptions to reduce the burden of the national opioid use epidemic. Adductor canal block (ACB) is a peripheral nerve block that has been shown to reduce pain and opioid usage with minimal effect on quadriceps function in patients undergoing arthroscopic knee surgery. Infiltration between Popliteal Artery and Capsule of the Knee (iPACK) block has also shown promise in reducing pain and opioid usage, specifically... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: Rothman Orthopaedic Institute, Philadelphia, Pennsylvania
Conditions: Pain, Postoperative
Assessing Dextenza Insert After SMILE Procedure
Completed
This three-month prospective, open-label, single-center, randomized investigator initiated clinical study seeks to investigate the efficacy of DEXTENZA when placed in the lower canaliculus (study eye) compared to topical corticosteroids (control eye) following bilateral SMILE surgery. In addition, the study will evaluate physician assessment of ease of DEXTENZA insertion
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: Cleveland Eye Clinic, Brecksville, Ohio
Conditions: Post Procedural Infection
Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax
Completed
This 6 month study seeks to compare the use of Intracanalicular Dexamethasone in conjunction with Restasis (cyclosporine ophthalmic emulsion) for the treatment of signs and symptoms of dry eye disease as compared to Restasis with Lotemax (loteprednol etabonate ophthalmic suspension 0.5%) and Restasis monotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: Cleveland Eye Clinic, Brecksville, Ohio
Conditions: Dry Eye
Pharmacologic Pretransplant Immunosuppression (PTIS) + Reduced Toxicity Conditioning (RTC) Allogeneic Stem Cell Transplantation in Inherited Hematologic Disorders
Withdrawn
To assess the outcomes of NRM when administering pharmacologic pretransplant immunosuppression (PTIS) followed by pretransplant reduced toxicity conditioning (RTC) and an allogeneic stem cell transplant (allo-SCT) and post-transplant graft-versus-host disease prophylaxis based on post-transplant cyclophosphamide (PT-Cy) in patients with inherited blood disorders.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/18/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Stem Cell Transplantation
The Bronchiolitis in Hospitalized Infants Study
Withdrawn
The goal of this clinical trial is to determine whether it is possible to identify, enroll, and deliver the study intervention (the corticosteroid dexamethasone) in hospitalized infants with bronchiolitis.
Participants in this study will be given two doses of dexamethasone within 72 hours of enrollment, followed by 30 days of safety monitoring.
Results of this feasibility pilot study may be used to inform the design of a future randomized controlled trial, whose results in turn could induce a... Read More
Gender:
ALL
Ages:
Between 0 months and 24 months
Trial Updated:
09/12/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas +1 locations
Conditions: Bronchiolitis
LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs
Completed
This will be a single-center, prospective, randomized controlled cross-sectional study comparing interscalene brachial plexus block with liposomal bupivacaine versus bupivacaine with epinephrine and PF dexamethasone in patients undergoing primary shoulder arthroplasty. Primary endpoint will be total opioid consumption in the first three post-operative days.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/11/2023
Locations: The Bone and Joint Institute at Hartford Hospital, Hartford, Connecticut
Conditions: Post-operative Pain, Total Shoulder Arthroplasty, Osteoarthritis of the Shoulder, Pain Management
Ixazomib Citrate, Pomalidomide, Dexamethasone, Stem Cell Transplant in Treating Relapsed or Refractory Multiple Myeloma
Completed
This phase II trial studies how well ixazomib citrate, pomalidomide, dexamethasone, and stem cell transplantation works in treating patients with multiple myeloma that has come back or does not respond to treatment. Giving chemotherapy, such as pomalidomide and dexamethasone, before a stem cell transplant helps kill any cancer cells that are in the body and helps make room in the patient?s bone marrow for new blood-forming cells (stem cells) to grow. After treatment, stem cells are collected fro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/01/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Recurrent Plasma Cell Myeloma, Refractory Plasma Cell Myeloma
Cabozantinib as a Targeted Strategy to Reverse Carfilzomib Resistance in Refractory Multiple Myeloma
Terminated
In the currently proposed phase I/II study, the investigators aim to treat patients with relapsed and/or relapsed refractory Multiple Myeloma who have progressed on carfilzomib-based therapy with an FDA approved c-MET inhibitor, cabozantinib.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
08/25/2023
Locations: University of Nebraska Medical Center, Omaha, Nebraska +1 locations
Conditions: Multiple Myeloma, Refractory Multiple Myeloma, Relapsed/Refractory Multiple Myeloma
A Study Evaluating Venetoclax (ABT-199) in Multiple Myeloma Subjects Who Are Receiving Bortezomib and Dexamethasone as Standard Therapy
Completed
This was a Phase 3, multicenter, randomized, double blind, placebo-controlled study evaluating the efficacy and safety of venetoclax plus bortezomib and dexamethasone in participants with relapsed or refractory multiple myeloma who are considered sensitive or naïve to proteasome inhibitors and received 1 to 3 prior lines of therapy for multiple myeloma.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
08/18/2023
Locations: Rocky Mountain Regional VA Medical Center/Eastern Colorado Health Care System /ID# 156524, Aurora, Colorado +96 locations
Conditions: Relapsed/Refractory Multiple Myeloma
Spinal Fusions Steroid Study
Enrolling By Invitation
Current efforts to improve pain alleviation focus on non-opioid pharmaceuticals. Intravenous perioperative corticosteroid administration has been suggested as an alternative method for post-operative pain control. The evidence regarding perioperative intravenous corticosteroids to help alleviate post-operative pain is mixed. Some meta-analyses report decreased opioid consumption and decreased pain intensity after a variety of surgical procedures. However, a study of larger orthopedic procedures... Read More
Gender:
ALL
Ages:
Between 10 years and 18 years
Trial Updated:
08/17/2023
Locations: Dell Children's Medical Center, Austin, Texas
Conditions: Spinal Fusion
Rituximab, Chemotherapy, and Filgrastim in Treating Patients With Burkitt's Lymphoma or Burkitt's Leukemia
Completed
RATIONALE: Monoclonal antibodies such as rituximab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Colony-stimulating factors such as filgrastim may increase the numbers of immune cells found in bone marrow or peripheral blood and may help a person's immune system recover from the side effects of chemotherapy. Combinin... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/16/2023
Locations: Naval Medical Center - San Diego, San Diego, California +30 locations
Conditions: Leukemia, Lymphoma
Nivolumab, Ixazomib, Cyclophosphamide, and Dexamethasone in Relapsed/Refractory Myeloma
Terminated
This research is being done to assess the effectiveness and safety of the combination of nivolumab with ixazomib, cyclophosphamide, and dexamethasone in relapsed and refractory multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts +1 locations
Conditions: Relapsed Multiple Myeloma, Refractory Multiple Myeloma
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