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Dexamethasone Treatment Options
A collection of 1455 research studies where Dexamethasone is the interventional treatment. These studies are located in the United States. Dexamethasone is used for conditions such as Multiple Myeloma, Lymphoma and Postoperative Pain.
697 - 708 of 1455
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A Study of Weekly Carfilzomib in Combination With Dexamethasone for Progressive Multiple Myeloma
Completed
The study had the following primary objectives:
* Phase 1: to determine the maximum tolerated dose (MTD) of once-weekly (QW) carfilzomib and dexamethasone for patients with relapsed or refractory multiple myeloma who have received 1 to 3 prior therapies
* Phase 2: to estimate the overall response rate (ORR) for patients with relapsed or refractory multiple myeloma who received 1 to 3 prior therapies treated with carfilzomib and dexamethasone QW at the MTD established in phase 1.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/12/2022
Locations: Arizona Oncology Associates, Tucson, Arizona +34 locations
Conditions: Multiple Myeloma
Once-weekly Versus Twice-weekly Carfilzomib in Combination With Dexamethasone in Adults With Relapsed and Refractory Multiple Myeloma
Completed
The purpose of the study is to compare the progression-free survival (PFS) of once-weekly carfilzomib dosing in combination with dexamethasone to twice-weekly carfilzomib dosing in combination with dexamethasone in adults with relapsed and refractory multiple myeloma, previously treated with bortezomib and an immunomodulatory agent (IMiD).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/09/2022
Locations: Research Site, Scottsdale, Arizona +139 locations
Conditions: Multiple Myeloma
Study Comparing Carfilzomib, Lenalidomide, and Dexamethasone (CRd) vs Lenalidomide and Dexamethasone (Rd) in Subjects With Relapsed Multiple Myeloma
Completed
The primary objective was to compare progression-free survival in adults with relapsed multiple myeloma who are receiving CRd vs participants receiving Rd in a randomized multicenter setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/08/2022
Locations: Mayo Clinic, Scottsdale, Arizona +126 locations
Conditions: Relapsed Multiple Myeloma
Steroids in Total Knee Arthroplasty
Terminated
The purpose of this study is to evaluate if the use of two small doses of intravenous (IV) steroids around the time of knee replacement surgery decrease a patient's pain or use of pain medication. The investigators will also determine if the subjects receiving the steroid will have better pain control and better postoperative outcomes after their surgery.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
09/06/2022
Locations: Emory Orthopedic and Spine Hospital, Tucker, Georgia
Phase III Study of Lenalidomide and Dexamethasone With or Without Elotuzumab to Treat Newly Diagnosed, Previously Untreated Multiple Myeloma
Completed
The purpose of the study is to determine whether the addition of Elotuzumab to Lenalidomide/low-dose Dexamethasone will increase the progression free survival (PFS)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/02/2022
Locations: Local Institution - 1628, Birmingham, Alabama +234 locations
Conditions: Multiple Myeloma
Hyper-CVAD With Liposomal Vincristine in Acute Lymphoblastic Leukemia
Completed
Any time the words "you," "your," "I," or "me" appear, it is meant to apply to the potential participant.
The goal of this clinical research study is to learn if intensive chemotherapy (hyper-CVAD therapy) given in combination with liposomal vincristine (Marqibo), in addition to rituximab for patients who are CD20 positive and/or imatinib, dasatinib, or ruxolitinib for patients with the Philadelphia (Ph) chromosome, can help to control ALL or lymphoblastic lymphoma. The safety of this treatment... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/31/2022
Locations: University of Texas MD Anderson Cancer Center, Houston, Texas
Conditions: Leukemia
Investigate, Following Cataract Surgery With IOL in Conjunction With Intracanalicular Dexamethasone Insert
Completed
Randomized, controlled treatment with an intracanalicular dexamethasone (0.4mg) insert following cataract surgery with intraocular lens implant (IOL) combined with minimally invasive glaucoma surgery (MIGS), specifically iStent, iStent inject or KDB in patients with primary open angle glaucoma (POAG) or ocular hypertension (OHTN)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/18/2022
Locations: Wolstan and Goldberg Eye Associates, Torrance, California
Conditions: Glaucoma, Primary Open Angle, Cataract
Regional Anesthesia to Reduce Opioid Use Following Functional Endoscopic Sinus Surgery
Completed
Opioids are prescribed for moderate to severe pain disorders; however, there are contraindications and side effects that are common to all opioids. The investigators hypothesize using regional anesthetic during sinus surgery will reduce surgical pain, therefore decreasing the need for post-operative opioid medication. The primary of objective is to determine if a long-acting local regional anesthetic applied during a surgery will reduce post-operative oral opioid usage.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2022
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pain Management
Hepatic Arterial Infusion in Treating Patients With Locally Advanced, Non-Metastatic Cholangiocarcinoma
Terminated
This pilot clinical trial studies the safety and effectiveness of continuous hepatic arterial infusion (HAI) of floxuridine (FUDR) alone or in combination with other chemotherapeutic drugs in treating patients with locally advanced cholangiocarcinoma that cannot be removed by surgery. HAI is a method to deliver higher concentrations of FUDR more directly to liver tumors and reduces side effects. HAI alone or in combination with oxaliplatin and/or gemcitabine may significantly improve clinical ou... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/08/2022
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Cholangiocarcinoma, Liver Neoplasms
A Safety and Efficacy Study of Carfilzomib and Pomalidomide With Dexamethasone in Patients With Relapsed or Refractory Multiple Myeloma
Terminated
This is a dose finding pilot study to evaluate the safety and determine the maximum tolerated dose of the combination of carfilzomib and pomalidomide with dexamethasone (CPD) in patients with relapsed or refractory multiple myeloma followed by a phase II expansion at the MTD to evaluate efficacy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/28/2022
Locations: Winship Cancer Institute of Emory University, Atlanta, Georgia +8 locations
Conditions: Multiple Myeloma
Total Therapy Study XVI for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia
Completed
The primary objective of this study (TOTXVI) is to compare the clinical benefit, the pharmacokinetics, and the pharmacodynamics of polyethylene glycol-conjugated (PEG) asparaginase given in higher dose (HD PEG) versus those of PEG-asparaginase given in conventional dose (CD PEG) during the continuation phase.
This study has several secondary objectives:
Therapeutic Objectives:
To estimate the event-free survival and overall survival of children with ALL who are treated with risk-directed ther... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
07/26/2022
Locations: St. Jude Children's Research Hospital, Memphis, Tennessee
Conditions: Acute Lymphoblastic Leukemia
Dextenza With ILUX for Treatment of MGD
Completed
To evaluate the benefit of treatment with a physician administered intracanalicular dexamethasone insert in evaporative dry eye disease (DED) patients with meibomian gland disfunction (MGD) and underlying inflammation undergoing iLUX MGD Treatment System.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/26/2022
Locations: Warrenville EyeCare & LASIK, Warrenville, Illinois
Conditions: Meibomian Gland Dysfunction, Evaporative Dry Eye
697 - 708 of 1455