Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer
Terminated
Depression is common in patients with cancer. Current medications for depression, while effective, take several weeks to take effect. Ketamine has emerged as a drug with promise for cancer patients. In two reported cases, a single dose of ketamine induced rapid and moderately sustained symptom reduction in depression and anxiety with no adverse side effects. Benefit was seen in as little as 1 hour and sustained up to 30 days. This study is a randomized, double-blind, placebo-controlled investiga... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2016
Locations: Mayo Clinic in Arizona, Scottsdale, Arizona +1 locations
Conditions: Cancer, Depression, Anxiety
Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery
Completed
The purpose of this research study is to evaluate the safety and analgesic efficacy of PMI-150 (intranasal ketamine) compared to placebo in patients with acute post-operative pain following orthopedic trauma, injury, or surgery.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/10/2012
Locations: Arizona Research Center, Phoenix, Arizona
Conditions: Pain, Postoperative