Morphine or Ketamine for Analgesia
NCT06835504
Not Yet Recruiting
Pain is common in children presenting to the emergency department but is frequently undertreated, leading to both short- and long-term consequences. Morphine is the standard treatment for children with moderate to severe acute pain, but its use is associated with serious side effects and caregiver and clinician concerns related to opioid administration. The investigators aim to determine if sub-dissociative ketamine is non-inferior to morphine for treating acute pain and a preferable alternative... Read More
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
02/17/2025
Locations: Children's Hospital Los Angeles, Los Angeles, California +1 locations
Conditions: Abdominal Pain, Isolated Extremity Fracture, Pain, Pediatrics
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ED Treatment of Suicidal Patients With Ketamine Infusion
NCT03502551
Withdrawn
This study aims to determine if a single intravenous (IV) dose of ketamine given in the emergency department (ED) can provide a long term reduction in suicidal ideation, lower time to ED discharge, and increase discharge to home or voluntary treatment facilities all while being safe.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/29/2019
Locations: University of California Davis Medical Center, Sacramento, California
Conditions: Suicide, Suicidal Ideation
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Biomarker Assessment of Glutamatergic Target Engagement
NCT02134951
Completed
The purpose of this study is to assess the relative feasibility of 2 potential functional measures of target engagement (Glx MRS, BOLD fMRI) to systematically assess mGluR 2/3 in drug development for psychotic spectrum disorders.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
08/15/2018
Locations: University of California Davis, Sacramento, California
Conditions: Healthy Controls
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