Testosterone Administration and ACL Reconstruction in Men
NCT01595581
Completed
This study is being done to test whether taking testosterone can prevent loss of muscle mass and strength due to anterior cruciate ligament (ACL) reconstructive surgery. Testosterone is the principal male sex hormone and an anabolic (muscle promoting) steroid. It is essential for the development of male reproductive tissues and promotes increased muscle, bone mass, and the growth of body hair. The investigators hope to learn whether testosterone given before and after ACL reconstructive surgery... Read More
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
02/08/2022
Locations: University of Southern California, Los Angeles, California
Conditions: Muscle Atrophy, ACL Reconstruction, Trauma, Osteoarthritis
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Cycled Testosterone Administration During Pulmonary Rehabilitation in Early Stage COPD
NCT03674320
Withdrawn
Chronic obstructive pulmonary disease (COPD) is characterized by chronic inflammation of the airways and/or damage to the lungs which leads to progressive impairment in airflow and the ability to breathe. COPD affects 6 to 20% of the US population and is among the leading causes for mortality in men and women. While COPD is principally a pathology of the airway, skeletal muscle wasting is a widely recognized comorbidity contributing to frequent and expensive hospital visits. Hospital readmissio... Read More
Gender:
ALL
Ages:
Between 40 years and 80 years
Trial Updated:
01/18/2022
Locations: University of Texas Medical Branch, Galveston, Texas
Conditions: COPD
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Effect of Androgel on Type 2 Diabetic Males With Hypogonadism
NCT00350701
Completed
This is to study the effect of replacing testosterone on different inflammatory cells in type 2 diabetics with low testosterone levels.
Gender:
MALE
Ages:
Between 35 years and 75 years
Trial Updated:
01/14/2022
Locations: Diabetes-Endocrinology Center of Western NY, 115 flint road, Buffalo, New York
Conditions: Diabetes Mellitus Type 2
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Hormone Suppression and Radiation Therapy for 6 Months With/Without Docetaxel for High Risk Prostate Cancer
NCT00116142
Completed
This randomized study is looking at the benefits of using docetaxel (chemotherapy) added to one of the standard treatments (radiation and hormones) for men with high-risk prostate cancer.
Gender:
MALE
Ages:
30 years and above
Trial Updated:
01/06/2022
Locations: Dana-Farber Cancer Institute and (Sanofi-Aventis Consortium), Boston, Massachusetts
Conditions: Prostate Cancer
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A Study of Megestrol Acetate Alone or in Combination With Testosterone Enanthate Drug in the Treatment of HIV-Associated Weight Loss
NCT00001079
Completed
To test the hypothesis that the predominant accrual of fat rather than lean body mass (LBM) that occurs during treatment of HIV-associated wasting with megestrol acetate may be improved by treatment with megestrol acetate and testosterone enanthate in combination. Body wasting is an increasingly frequent AIDS-defining condition in individuals infected with HIV. Increasing caloric intake fails to consistently restore lean tissue patients with HIV associated weight loss. Megestrol acetate has bee... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/28/2021
Locations: USC CRS, Los Angeles, California +20 locations
Conditions: HIV Infections, HIV Wasting Syndrome
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Testosterone for HIV-Positive Men With Reduced Serum Testosterone Levels and Abdominal Fat
NCT00009555
Completed
The purpose of this study is to see if treatment with testosterone will reduce abdominal fat in HIV-positive men. Many HIV patients on antiretroviral therapy show an increase in abdominal fat. Studies have shown that treatment with testosterone may decrease abdominal fat. This study will determine if testosterone will reduce abdominal fat in HIV patients.
Gender:
MALE
Ages:
Between 18 years and 70 years
Trial Updated:
10/28/2021
Locations: USC CRS, Los Angeles, California +26 locations
Conditions: HIV Infections
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Safety and Efficacy of LibiGel® for Treatment of Hypoactive Sexual Desire Disorder in Postmenopausal Women
NCT00612742
Completed
This study is a randomized, double-blind, placebo-controlled, adaptive design, multi-center study of the long-term cardiovascular and breast safety of LibiGel in the treatment of HSDD in postmenopausal women with at least two points of cardiovascular risk and clinical diagnosis of Hypoactive Sexual Desire Disorder (HSDD).
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
10/27/2021
Locations: BioSante Site #215, Birmingham, Alabama +148 locations
Conditions: Hypoactive Sexual Desire Disorder
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The Effect of Testosterone Replacement on Bone Mineral Density in Boys and Men With Anorexia Nervosa
NCT00853502
Withdrawn
Decreased bone strength is a common and serious medical problem present in many people with anorexia nervosa. Men with anorexia nervosa have lower levels of gonadal steroids such as testosterone. Low testosterone levels have been shown to result in low bone density. We are investigating whether bone mineral density and bone microarchitecture are abnormal in males with anorexia nervosa and whether supplementation with testosterone would improve both bone mineral density and bone microarchitectur... Read More
Gender:
MALE
Ages:
Between 14 years and 30 years
Trial Updated:
10/22/2021
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Bone Metabolism
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Natesto Effects on Testosterone, Luteinizing Hormone, Follicle Stimulating Hormone and Semen Parameters
NCT03203681
Completed
Low testosterone affects more than 10% of men worldwide, with high incidence in the elderly.This will be a prospective case study. The investigators will identify men with hypogonadism in our clinic interested in Natesto for testosterone replacement therapy (TRT). Natesto is a relatively new form of testosterone replacement therapy that is delivered intranasal to men diagnosed with low testosterone. Current advantages to Natesto include ease of delivery and decreased risk of transference. Recent... Read More
Gender:
MALE
Ages:
Between 18 years and 55 years
Trial Updated:
09/28/2021
Locations: University of Miami, Miami, Florida
Conditions: Hypogonadism, Male
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Effects and Safety of OPK-88004 Doses in Men With Signs and Symptoms of Benign Prostatic Hyperplasia (BPH)
NCT03297398
Terminated
This study will evaluate the safety and effectiveness of different doses of OPK-88004 compared to placebo on serum PSA compared to placebo in men with benign prostatic hyperplasia (BPH).
Gender:
MALE
Ages:
45 years and above
Trial Updated:
08/23/2021
Locations: Pinnacle Research Group, Anniston, Alabama +14 locations
Conditions: Benign Prostatic Hyperplasia
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Optimizing Protein Intake in Older Americans With Mobility Limitations
NCT01275365
Completed
This will be a randomized, placebo-controlled, parallel group, double blind, clinical trial in community dwelling, older men, 65 years of age or older, who have mobility limitation and low protein intake. The study will have a 2 X 2 factorial design, which will allow us to investigate the effects of dietary protein intake and testosterone separately and together.
Gender:
MALE
Ages:
65 years and above
Trial Updated:
07/27/2021
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Mobility Limitation
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Study of Psychological and Motor Effects of Testosterone in Adolescents With XXY/Klinefelter Syndrome
NCT01585831
Completed
The purpose of this study is to determine if testosterone replacement therapy leads to changes in psychological factors and/or motor skills in adolescent males with 47,XXY (also called Klinefelter syndrome). This study will also evaluate whether certain genetic factors of the X chromosome affect the psychological or motor features of XXY/Klinefelter syndrome.
Gender:
MALE
Ages:
Between 8 years and 18 years
Trial Updated:
07/16/2021
Locations: Childrens Hospital Colorado, Aurora, Colorado
Conditions: Klinefelter Syndrome, XXY Syndrome
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