Effect of Increasing Testosterone on Insulin Sensitivity in Men With the Metabolic Syndrome
Terminated
The purpose of the study is to examine the effect of testosterone treatment on insulin in men with the metabolic syndrome with testosterone levels at or below the lower end of the normal range.
Gender:
MALE
Ages:
Between 50 years and 75 years
Trial Updated:
04/14/2017
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Metabolic Syndrome
TOM: Testosterone in Older Men With Sarcopenia
Terminated
The purpose of this study is to determine whether testosterone replacement in older men with low testosterone levels will increase muscle strength, improve physical performance and overall sense of well being, and reduce fatigue.
Gender:
MALE
Ages:
65 years and above
Trial Updated:
02/22/2017
Locations: Boston University Medical Center, Boston, Massachusetts +1 locations
Conditions: Sarcopenia, Hypogonadism, Muscular Diseases
Androgen Regulation of Priapism in Sickle Cell Disease
Withdrawn
It is believed that when androgen (testosterone) levels are below normal there is a disturbance of normal bodily functioning that is associated with priapism in some men. Conversely, it is believed that testosterone replacement will improve the condition of priapism when the testosterone levels are brought to normal. In turn, this will also improve psychological well being in men with sickle cell disease (SCD).
Gender:
MALE
Ages:
Between 18 years and 50 years
Trial Updated:
01/18/2017
Locations: Johns Hopkins University School of Medicine, Johns Hopkins Hospital, Baltimore, Maryland
Conditions: Priapism, Sickle Cell Disease, Hypogonadism
The Cardiac Benefit of Testosterone Replacement in Men With Low Testosterone Levels With Coronary Artery Disease After Successful Intervention of the Blockage or Narrowed Heart Artery
Completed
The purpose of the study is to find out if giving the study drug, Androgel (testosterone) as a testosterone replacement help bring the testosterone to an acceptable level and to find out if it will help improve heart condition in males with coronary artery disease (CAD) following successful percutaneous coronary intervention.
Gender:
MALE
Ages:
Between 40 years and 75 years
Trial Updated:
11/07/2016
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Coronary Artery Disease
Bipolar Androgen-based Therapy for Prostate Cancer (BAT)
Completed
The purpose of this study is to determine the safety and clinical effects of alternating androgen deprivation therapy with testosterone therapy in men with recurrent prostate cancer as first line hormonal therapy, to assess the effect of alternating therapy on quality of life and metabolic changes associated with androgen-deprivation therapy.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
10/10/2016
Locations: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland
Conditions: Recurrent Prostate Cancer
Testosterone Replacement for Fatigue in Male Hypogonadic Advanced Cancer Patients
Completed
The goal of this clinical research study is to learn if and how testosterone replacement therapy may affect fatigue in males with advanced cancer and low testosterone levels.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
07/26/2016
Locations: The DeBakey VA Medical Center/Baylor College of Medicine, Houston, Texas +1 locations
Conditions: Advanced Cancer
Low-Dose Testosterone in Improving Libido in Postmenopausal Female Cancer Survivors
Completed
RATIONALE: The hormone testosterone may improve the libido (sex drive) in women. It is not yet known whether testosterone is effective in improving libido in female cancer survivors. PURPOSE: This randomized phase III trial is studying how well low-dose testosterone works to improve libido in postmenopausal cancer survivors.
Gender:
FEMALE
Ages:
All
Trial Updated:
07/12/2016
Locations: CCOP - Mayo Clinic Scottsdale Oncology Program, Scottsdale, Arizona +15 locations
Conditions: Cancer Survivor, Sexual Dysfunction, Sexuality and Reproductive Issues, Unspecified Adult Solid Tumor, Protocol Specific
Compromised Microcirculation in Women With Polycystic Ovary Syndrome
Completed
The scientific aims of the study are to determine how peripheral microcirculatory responsiveness is altered in obese women with Polycystic Ovary Syndrome (PCOS) during local heating and to determine the mechanism for testosterone effects on peripheral microcirculatory responsiveness in women with PCOS.
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
07/01/2016
Locations: John B. Pierce Laboratory, New Haven, Connecticut
Conditions: Polycystic Ovary Syndrome
Chemotherapy and Radiation in Treating Participants With Stage 3 Non-Small Cell Lung Cancer
Completed
This study will compare the overall survival of participants with locally-advanced, Stage III Non-Small Cell Lung Cancer (NSCLC) with nonsquamous cell histology.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/20/2016
Locations: For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Birmingham, Alabama +132 locations
Conditions: Non Small Cell Lung Cancer
Oral Testosterone for the Treatment of Hypogonadism in Males
Completed
Low testosterone is a condition that occurs when the body is unable to produce sufficient quantities of testosterone. The medical name for low testosterone is hypogonadism. Hypogonadism can be caused by many factors. Symptoms include: decrease in libido, lack of energy and mood swings. The goal of testosterone replacement therapy is to return testosterone levels to the normal range and relieve symptoms.
Gender:
MALE
Ages:
Between 18 years and 70 years
Trial Updated:
04/21/2016
Locations: San Diego Sexual Medicine, San Diego, California
Conditions: Hypogonadism
A Pilot Study of Parenteral Testosterone and Oral Etoposide as Therapy for Men With Castration Resistant Prostate Cancer
Completed
The objective of the study is to determine if men with evidence of progressive prostate cancer while on chronic androgen ablation of ≥ 1 year duration will exhibit a clinical response following administration of parenteral testosterone and oral etoposide. Treatment Plan: Eligible patients will continue on androgen ablative therapy with luteinizing hormone-releasing hormone (LHRH) agonist (i.e. Zoladex or Lupron) if not surgically castrated. Patients will receive intramuscular injection with tes... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
04/05/2016
Locations: Johns Hopkins School of Medicine - Sidney Kimmel Comprehensive Cancer Center, Baltimore, Maryland
Conditions: Prostate Cancer
Rapid Hormonal Cycling as Treatment for Patients With Prostate Cancer: The Men's Cycle
Completed
Objective: To determine the response to rapid hormonal cycling in patients with non-castrate prostate cancer.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
02/24/2016
Locations: Memorial Sloan Kettering Cancer Center, New York, New York
Conditions: Prostate, Cancer, Hormonal Cycling